Gene Information

Name : fliI (y2479)
Accession : NP_669785.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2743187 - 2744665 bp
Length : 1479 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGCCAGTCTGGCGACCCGTTGGCATGAACTGTGCCGTCTGGCCGCGCCGGGGGAACTGTGATGCCCCCCGCCTCAGCCG
CTGGCTTACCTCTTTAGATAAATTCGAAGAGCGTATCAGCCAAACGACAACAATCCGCCGTTATGGCCGCTTGACCCGCG
CCACCGGTTTAGTGCTGGAAGCCACTGGTCTGCAATTGCCGTTAGGGGCGACCTGTCTGATTGAGCGCCATAATGGCGGT
GAAGTGCAGGAAGTCGAAAGCGAAGTGGTTGGTTTTAACGGTCAGCATCTGTTTCTTATGCCTTTGGAAGATGTGGAAGG
TATCGTCCCCGGTGCCAGAGTGTATGCCCGAGTCACCACCAGCGGCACGTCTGCCAGTAAACAGTCAATTTCTAGTAAAC
AATCAATTCCCAGTAAACAATCATTCGCCAGTAAACAATTACCCCTTGGCCCCGAGTTATTGGGCCGGGTATTGGATGGC
AGTGCCAAACCGCTTGATGGCTTACCGGCACCTGAAACCGGTTATCGTGCACCACTGATTACACCACCGATAAACCCTTT
GCAACGCACCGCCATTGTCCAAGTCTTGGATGTGGGCGTGCGTACCATTAACGCCTTGTTGACGGTCGGGCGCGGCCAGC
GGATGGGGCTGTTTGCTGGCTCTGGGGTTGGCAAAAGCGTACTGCTCGGCATGATGGCCCGTTACACACAGGCTGACGTG
ATCGTGGTTGGGCTGATTGGTGAGCGTGGCCGTGAAGTCAAAGATTTTATCGAAAATATTCTCGGGGCTGAAGGCCGTGC
CCGTTCGGTGGTTATCGCCGCGCCAGCCGATGTGTCACCGTTGCTGCGTATGCAAGGTGCCGCCTATGCCACCCGTATTG
CCGAAGATTTCCGCGATCGTGGTCAGCATGTGTTGCTAATTATGGACTCCCTAACCCGCTATGCCATGGCGCAACGTGAA
ATCGCGCTGGCTATCGGCGAGCCTCCCGCGACCAAAGGTTATCCGCCCTCCGTCTTCGCCAAATTACCGGCACTGGTTGA
ACGGGCGGGTAACGGTGTTTCAGGCGGCGGCTCCATTACCGCATTTTATACCGTCCTCACCGAAGGTGATGATCAGCAAG
ATCCTATTGCTGACTCTGCGCGCGCCATCCTCGATGGCCATGTGGTGCTATCTCGCCGTTTGGCTGAATCCGGTCACTAT
CCGGCTATCGATATCGAAGCCTCTATCAGCCGTGCCATGACCTCATTAATCGATGATGACCATTACAGCCGGGTGCGCCA
GTTTAAACAACTGCTTGCCAGTTATCAGCGTAACCGCGATTTGATCAGTGTCGGGGCTTATGCTGCGGGCAGTGATCCCT
TATTGGACAAGGCGATTGCCCTGTACCCACAGATGGAGGCTTTCTTGCAGCAAGGCATGTTTGAGCGCAGCAGTTTTGAT
GATGCCTGCCAGCATTTGAAGGTTTTATTTCCAGGATAA

Protein sequence :
MPVWRPVGMNCAVWPRRGNCDAPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGG
EVQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDG
SAKPLDGLPAPETGYRAPLITPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADV
IVVGLIGERGREVKDFIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQRE
IALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHY
PAIDIEASISRAMTSLIDDDHYSRVRQFKQLLASYQRNRDLISVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFD
DACQHLKVLFPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-65 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-65 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-66 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-66 47
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-60 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-60 46
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-75 45
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-75 45
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-75 45
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-75 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-76 45
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-75 45
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-75 45
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-72 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-72 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 9e-58 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-62 41
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI NP_669785.1 flagellum-specific ATP synthase VFG2331 Protein 0.0 92
fliI NP_669785.1 flagellum-specific ATP synthase VFG2499 Protein 1e-141 66
fliI NP_669785.1 flagellum-specific ATP synthase VFG1254 Protein 9e-117 59
fliI NP_669785.1 flagellum-specific ATP synthase VFG2459 Protein 8e-58 45
fliI NP_669785.1 flagellum-specific ATP synthase VFG0192 Protein 4e-76 44
fliI NP_669785.1 flagellum-specific ATP synthase VFG2144 Protein 2e-79 43
fliI NP_669785.1 flagellum-specific ATP synthase VFG0390 Protein 8e-72 42