Gene Information

Name : y2393 (y2393)
Accession : NP_669700.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Unknown
Product : prophage integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 2645673 - 2646935 bp
Length : 1263 bp
Strand : +
Note : residues 1 to 420 of 420 are 100.00 pct identical to residues 1 to 420 of 420 from GenPept : >gb|AAC69581.1| (AF091251) CP4-like integrase [Yersinia pestis]

DNA sequence :
ATGTCCCTTACCGACGCAAAAATCCGCACCCTCAAGCCTTCTGATAAACCCTTTAAAGTCTCCGATTCTCACGGTCTGTA
TCTGCTGGTCAAGCCGGGTGGCTCCCGCCACTGGTATCTCAAATACCGTATTAGCGGTAAAGAATCCCGCATTGCGCTGG
GTGCCTATCCAGCCATCTCCCTGTCTGATGCGCGACAGCAACGTGAAGGTATCCGTAAAATGCTGGCGCTGAATATCAAC
CCGGTACAGCAGCGGGCTGCTGAACGTGGCTCACGAACACCGGAGAAAGTTTTTAAAAACGTGGCGCTGGCGTGGCATAA
AAGTAACAGGAAATGGTCGCAGAACACCGCCGACCGTCTGCTTGCCAGCCTGAACAATCACATCTTTCCGGTCATCGGGA
ACCTACCTGTATCAGAACTTAAACCCCGTCATTTCATTGACCTGCTGAAAGGGATCGAGGAAAAAGGTCTGCTGGAGGTT
GCGTCCCGCACACGGCAGCACCTGAGTAACATAATGCGCCATGCGGTCCATCAGGAGTTAATCGATACGAACCCTGCAGC
AAACCTTGGCGGCGTGACCACACCTCCTGTCAGACGGCACTATCCTGCCCTGCCGCTGGAGCGGCTGCCTGAACTGCTTG
AACGTATTGGGGCATATCATCAGGGCCGTGAACTGACCCGGCATGCCGTTCTGCTGATGCTGCATGTGTTCATTCGCTCC
AGTGAACTGCGTTTCGCCCGCTGGTCAGAGATTGATTTCACAAACCGAGTCTGGACGATACCCGCGACGCGAGAACCCAT
TATTGGCGTGCGTTATTCCGGCCGCGGGGCAAAAATGCGAATGCCGCATATCGTCCCCCTCTCAGAACAGTCCATCGCCA
TTCTGAAACAGATTAAGGATATCACCGGTAATAATGAACTGATCTTCCCCGGCGACCATAACCCGTATAAGCCAATGTGT
GAAAACACGGTCAATAAGGCACTGCGGGTGATGGGTTACGACACGAAAAAGGATATCTGCGGTCACGGCTTCCGGGCAAT
GGCATGCAGTGCGCTGATGGAATCGGGTTTATGGGCAAAGGACGCAGTAGAACGCCAGATGAGTCATCAGGAGCACAATA
CCGTGCGCATGGCTTATATTCATAAGGCAGAGCACCTAGAAGCCCGCAAAGCGATGATGCAGTGGTGGTCGGATTATCTG
GAAGCATGCCGAGAATCTTATGCACCGCCTTATACAATTGGTAAAAATAAGTTTATCCCATAG

Protein sequence :
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRISGKESRIALGAYPAISLSDARQQREGIRKMLALNIN
PVQQRAAERGSRTPEKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQEHNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int YP_002346908.1 integrase Not tested HPI Protein 0.0 100
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 0.0 100
int2 NP_993013.1 integrase Not tested HPI Protein 0.0 100
int CAA21384.1 - Not tested HPI Protein 0.0 100
unnamed AAD17660.1 unknown Not tested HPI Protein 0.0 99
int CAB59974.1 integrase Not tested HPI Protein 0.0 99
int CAA08754.1 integrase Not tested HPI Protein 0.0 99
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 4e-135 99
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 9e-150 99
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 1e-116 59
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 1e-116 59
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 1e-106 56
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 7e-113 56
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 7e-113 56
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 2e-106 55
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 2e-106 55
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 1e-106 55
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 2e-106 55
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 3e-106 55
int AAK00456.1 Int Not tested SHI-1 Protein 5e-98 55
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 1e-101 55
int AAL51028.1 CP4-like integrase Not tested LEE Protein 7e-108 55
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 9e-108 55
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 2e-106 55
int-phe AAL60261.1 Int-phe Not tested LEE Protein 7e-108 55
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 5e-108 55
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-108 55
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-108 55
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 2e-107 55
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 5e-107 55
int AAL51003.1 CP4-like integrase Not tested LEE Protein 1e-107 55
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-107 55
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 7e-108 55
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 9e-108 55
int CAC81896.1 integrase Not tested LEE II Protein 2e-99 55
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 6e-92 49
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 1e-95 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
y2393 NP_669700.1 prophage integrase VFG0626 Protein 6e-107 55
y2393 NP_669700.1 prophage integrase VFG1536 Protein 6e-102 55
y2393 NP_669700.1 prophage integrase VFG1693 Protein 1e-107 55