Gene Information

Name : topB (y2156)
Accession : NP_669467.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 2383208 - 2385133 bp
Length : 1926 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGACTGTTTATTGCCGAAAAACCCAGTTTAGCGCGAGCGATTGCAGATATTTTGCCAAAACCGCATCGTCGAGGTGA
TGGATTCATCGCCTGTGGTAATGATCAAATGGTGACCTGGTGTGTTGGTCATTTACTCGAACAAGCCCAGCCGGATGCTT
ATGACAGCCGTTATGCACGTTGGTCATTAGCGGACTTACCGATCATTCCTGAAAAATGGCAGCTACAACCTCGTCCTTCC
GTCAGCAAACAACTCAATGTGATTAAGCAACTGTTACAGCAAGCCGATGAAGTGGTCCATGCTGGCGACCCGGATAGAGA
AGGGCAACTGTTAGTTGATGAGGTGCTGGATTATTTGGGATTGGCCGCAGAGAAACGGCAAAATGTTCGTCGTTGCTTGA
TTAACGATTTAAACCCACAGGCGGTTGAGCGTGCAGTGGAGCGCTTGCGTTATAACCGCGAGTTTATCCCGCTGTGTGTT
TCTGCGTTGGCTCGAGCCAGAGCCGATTGGCTCTATGGCATCAATATGACTCGCGCCTATACCATTCTTGGGCGCAATGC
GGGCTATGACGGTGTTTTATCCGTCGGGCGGGTACAAACGCCCGTATTGGGGCTGGTTGTTCGCCGTGATGAAGAGATTG
AAAGCTTCATTCCCAAAGATTTTTTTGAAGTTAAAGCCCACATAGTGACGCCTGCAGACGAACGTTTTATTGCTCTCTGG
CAGCCGAGTGACTCCTGCGAATCTTATCAGGACGAAGAAGGGCGCTTGTTGCATCGGCCGCTTGCAGAACATGTTGTCAA
TCGCATAACCGGCCAGCCCGCGCTGGTGACATCCTATAATGATAAACGGGAATCGGAAACGGCACCGTTGCCATTCTCCT
TGTCTACATTACAAATCGAAGCTGCAAAACGTTTCGGCCTCAGTGCTCAGCAAGTATTGGATATTTGCCAACGGTTGTAT
GAAACGCACAAATTGATTACGTATCCCCGTTCGGATTGCCGATATCTACCTGAAGAGCATTTTGCCGGGCGTCATTCGGT
GCTTAATGCCATTAGTCTTCATCAGTCAGACCTTTTGCCGCTTGAGGTCATGGATAGTGATCGGCGCAACCGCTGCTGGG
ATGATAAAAAAGTCGATGCGCACCACGCTATTATCCCAACCGCACGTGCCAGCAAAGTGAATTTGACGACGGATGAAGGC
AAAGTATACCGGTTGGTGGCACAGCAATATCTGATGCAATTCTGTCCAGATGCACAGTTCCGTAAGTGTGTGATTGAATT
GGATATCGCTGGCGGGAAATTTATTGCCAAGGCACGCTTTTTGGCCGAGGCGGGATGGCGGACCTTACTGGGCAGTAAAG
AGCGTGATGAAGAGAACGAAGGAGCGCCATTGCCGGTGGTAGCCAAAGGGGCTGAATTATTATGCGAACGCGGTGAGGTT
GTTGAACGACAAACTCAGCCACCCCGGCCTTTCACCGACGCCAGTTTATTATCGGCGATGACAGGAATTGCGCGTTTCGT
ACAGGATAAAGAACTGAAAAAAGTTTTGCGAGCCACCGATGGCTTGGGTACGGAAGCCACTCGAGCAGGTATTATCGAAC
TGCTCTTCAAGCGCACTTTTCTCTTTAAGAAAGGGCGTTATATACATGCCAGCCCTGCGGGACGCGCGTTGATTCATGCA
TTACCGGATATTGCGGCACGGCCAGATATGACAGCACATTGGGAATCAACGTTGACACAAATCAGTGAAAAAAACTGCCG
CTATCAAGATTTTATGCAACCACTGGTGATGACATTGCAGGATTTAATTAGTCAGGCGAAACAAAATCGTTCTCCACAGG
TTTTCCGTGGGTTACCCGTCGGCCCTTCAGGGGCACCCAAGAAACGTAAAAAAATATCGTCTAAGGCCAAGGAGAGTAAA
TCATGA

Protein sequence :
MRLFIAEKPSLARAIADILPKPHRRGDGFIACGNDQMVTWCVGHLLEQAQPDAYDSRYARWSLADLPIIPEKWQLQPRPS
VSKQLNVIKQLLQQADEVVHAGDPDREGQLLVDEVLDYLGLAAEKRQNVRRCLINDLNPQAVERAVERLRYNREFIPLCV
SALARARADWLYGINMTRAYTILGRNAGYDGVLSVGRVQTPVLGLVVRRDEEIESFIPKDFFEVKAHIVTPADERFIALW
QPSDSCESYQDEEGRLLHRPLAEHVVNRITGQPALVTSYNDKRESETAPLPFSLSTLQIEAAKRFGLSAQQVLDICQRLY
ETHKLITYPRSDCRYLPEEHFAGRHSVLNAISLHQSDLLPLEVMDSDRRNRCWDDKKVDAHHAIIPTARASKVNLTTDEG
KVYRLVAQQYLMQFCPDAQFRKCVIELDIAGGKFIAKARFLAEAGWRTLLGSKERDEENEGAPLPVVAKGAELLCERGEV
VERQTQPPRPFTDASLLSAMTGIARFVQDKELKKVLRATDGLGTEATRAGIIELLFKRTFLFKKGRYIHASPAGRALIHA
LPDIAARPDMTAHWESTLTQISEKNCRYQDFMQPLVMTLQDLISQAKQNRSPQVFRGLPVGPSGAPKKRKKISSKAKESK
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 1e-106 41
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 1e-107 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 2e-103 41