Gene Information

Name : y1538 (y1538)
Accession : NP_668858.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : Clp ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1702814 - 1705564 bp
Length : 2751 bp
Strand : +
Note : residues 26 to 909 of 916 are 87.66 pct identical to residues 1 to 883 of 890 from GenPept : >gb|AAG00524.1|AF285784_1 (AF285784) Clp protease-associated protein ClpB [Yersinia enterocolitica]

DNA sequence :
ATGGTGCATCAAGCATTATTTCATGAACAATTTAAACTACACATGAACGCCGTTAAAAAGACCAGGATAAAAAACGTGGC
TATTACAAGGAAACATCTCTTCGGCAAGCTGGACGCCACTCTTTTCAAAGGTATTGAAAGCGCAACAACGATTTGTAAAT
TACGCGGCAATCCTTACGTAGAGTTAGTTCACTGGTTGAATCAGCTTTGGCATCAGGAAGATAACGACCTTAAGCAGATT
ATTCGGTATTTTGCGGTGGATGTGGATGCCTTTGAGCGTGAACTGGCTCAGGCACTTGCGAAGTTACCTGTTGGGGCAAC
TAGCATTTCAGATTTTTCGTATCATATTGAGTTGGCCACGGAACGGGCTTGGATCTATGCCAGCCTGGAGTGTTTAGATA
CCCGTATCCGCAGCGGACATCTGCTGCTTGCGCTATTAACCACAATGGAACTGCGGAGAGCTTTCTTTGCGATTGCGCCA
AGCATGGAAAAAATTCCATTAGAGCATTTAAGCAAAGATTTGAACTTCATTACGCAGGCATCACCAGAAGCGAATGAAGC
CGCCAGTGATGGCAGCCCGTTGTACGATGGTGCTTTACCTGGCGAAGCCAGTAATGCCATTGGTGCAGCCAAAAGTGGTG
GCGCACTGGCTCAATACACCACAGACCTCACGGCATTAGCACGTGAAGGCAAGATAGATCCGGTATTGGGACGTAATCAC
GAAATCAACACAATGGTTGATATTCTCTTGCGCCGTCGGCAGAACAACCCATTACTTACCGGTGACGCAGGGGTGGGTAA
AACCGCCATTGTTGAAGGGCTAGCATTGGCTATTGCTGCTGGCTCAATGCCACCAGCATTAAGCCAGGTAAGCCTGTTGT
CATTAGATATTGTGGCGCTCTCAGCGGGTGCCAGCATGAAAGGTGAATTTGAAGCGCGCCTGAAGAGTGTCTTGGATGAA
GCGATAGCGGCAGAAAAGCCCGTTATTTTGTTTATCGATGAAGTACACACACTTATTGGCGCGGGTGGCAATGCCGGGAC
CGGCGATGCGGCGAACTTATTGAAACCTGCATTGGCGCGTGGCCAGTTACGTACCATTGGTGCGACAACGTGGAGCGAGT
TCAAGCGTCACATTGAGAAGGATCCGGCACTCACCCGTCGTTTCCAAGTACTTCAAGTTGATGAGCCCGATGAGAACACG
GCGATCTCCATGTTACGGGGCCTGATACCTGCGCTAGAAAAGCACCACGGCGTGTGGATTATGGACGAAGCTTTACAGGC
GGCAGTACGGTTGTCTCATCGTTATATCCCTGCGCGTCAGTTGCCGGATAAAGCGATAAGTCTGCTTGATACGGCTTGTG
CACGGATCGCTGTCGCGCAGTTTTCACAACCAATAGAGCTACAGCACTTAACCTTCCAGAGTGAGACGGCGCAAACTGAG
CTGGTTTCCTTAGAGAAAGCGCGGCACTTTGGTAAAGCGCAGGATGCGCGTACTGAGCAGTTGAAAACATCCATTGCTGA
ACATGGCGAGGCTGCGGATAAGCTTGATCAGCGTTGGCAGGCAGAACGCGAATTGGTATCAGCGATTACGACCATAAGAA
CCGCACTGTATGACTTGGTTTCTCAGCCAGAGCCTGATGAGGAAAAACGTCGGGCTTATCAAGCGCAATTAGTTCAGTTG
GAAGCGCAGCTTTCTCAGGTTCGCACTTCACTGCCGTTAGTGCAGACAGAAGTCAACGCTGAAGTGATTGCCAGTATCGT
TGCGGATTGGACCGGCATTCCGGTTGGGCAAATGCTCAAAGACGATATTCGGGCGGTAATGGAGTTGCCACAGCGCCTTG
AAGCACGTGTTATTGGTCAGCCCCATGCATTGATGCAACTGGGTGAAAATATTATGACCGCACGCGCTGGCCTGTCAGAC
CCAAGGAAACCATTGGGGGTCTTTATGTTAGTGGGGCCTTCAGGTGTGGGTAAAACAGAGACGGCCTTAGCGATCGCCGA
GAGCATGTATGGTGGTGAACAGAATATGATCACTATCAATATGAGCGAATATCAGGAATCGCATACCGTTTCCTCTTTAA
AAGGTTCTCCACCGGGATATGTTGGATACGGTGAAGGCGGTGTGTTAACGGAAGCTGTGCGCCGTAAGCCATATAGTGTT
GTGTTGTTAGATGAAATCGAAAAAGCGCACTCTGATGTACATGAGTTATTCTTCCAAGTGTTTGATAAAGGCCAAATGGA
AGATGGTGAAGGGCGTTTTATCGATTTTAAAAATACTATCTTGTTGTTAACCAGTAATGTGGGCAGCGAGTTACTGAGTA
ACTTATTAGCTGATCCAGATACTGCACCGGATCAGGATGGAATATTAAGTGCGTTGCAACCTGAATTGCTGAAAGTTTTC
CCCGCAGCATTTTTAGGGCGAGTTACGGTTATTCCTTATCTTCCGTTACAGCAAGATGCATTGCAGCATATTGTACGGTT
GCATTTAGATCGGATTGGCGCTCGTTTATACTCGCAGCATCAATTGACACTGAAATACAGTGATGAAGTGGTTGAAGATG
TTGTTAGCCGCTGTGCGGTCTCAGAGACCGGTGCGCGTATGCTGATCCGTTACATTGAACAAAATATTACGCCAAAAATA
GGTAAATATATTTTAGGTGATAGTGATGTGAAGCCTGAGCAAATTATTTTCGTTCATAAAAATGAAAATGGATTCGTGAT
CGCTTTACAGTGTAAAGATGACGAAAACTAA

Protein sequence :
MVHQALFHEQFKLHMNAVKKTRIKNVAITRKHLFGKLDATLFKGIESATTICKLRGNPYVELVHWLNQLWHQEDNDLKQI
IRYFAVDVDAFERELAQALAKLPVGATSISDFSYHIELATERAWIYASLECLDTRIRSGHLLLALLTTMELRRAFFAIAP
SMEKIPLEHLSKDLNFITQASPEANEAASDGSPLYDGALPGEASNAIGAAKSGGALAQYTTDLTALAREGKIDPVLGRNH
EINTMVDILLRRRQNNPLLTGDAGVGKTAIVEGLALAIAAGSMPPALSQVSLLSLDIVALSAGASMKGEFEARLKSVLDE
AIAAEKPVILFIDEVHTLIGAGGNAGTGDAANLLKPALARGQLRTIGATTWSEFKRHIEKDPALTRRFQVLQVDEPDENT
AISMLRGLIPALEKHHGVWIMDEALQAAVRLSHRYIPARQLPDKAISLLDTACARIAVAQFSQPIELQHLTFQSETAQTE
LVSLEKARHFGKAQDARTEQLKTSIAEHGEAADKLDQRWQAERELVSAITTIRTALYDLVSQPEPDEEKRRAYQAQLVQL
EAQLSQVRTSLPLVQTEVNAEVIASIVADWTGIPVGQMLKDDIRAVMELPQRLEARVIGQPHALMQLGENIMTARAGLSD
PRKPLGVFMLVGPSGVGKTETALAIAESMYGGEQNMITINMSEYQESHTVSSLKGSPPGYVGYGEGGVLTEAVRRKPYSV
VLLDEIEKAHSDVHELFFQVFDKGQMEDGEGRFIDFKNTILLLTSNVGSELLSNLLADPDTAPDQDGILSALQPELLKVF
PAAFLGRVTVIPYLPLQQDALQHIVRLHLDRIGARLYSQHQLTLKYSDEVVEDVVSRCAVSETGARMLIRYIEQNITPKI
GKYILGDSDVKPEQIIFVHKNENGFVIALQCKDDEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 0.0 58
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 7e-130 46
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 9e-130 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
y1538 NP_668858.1 Clp ATPase VFG2076 Protein 0.0 55
y1538 NP_668858.1 Clp ATPase VFG2084 Protein 3e-138 44