Gene Information

Name : ssa (SpyM3_0920)
Accession : NP_664724.1
Strain : Streptococcus pyogenes MGAS315
Genome accession: NC_004070
Putative virulence/resistance : Virulence
Product : streptococcal superantigen SSA - phage associated
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 977738 - 978520 bp
Length : 783 bp
Strand : -
Note : best blastp hit: gb|AAB02148.1| (U48792) superantigen SSA [Streptococcus pyogenes], and gb|AAB02150.1| (U48794) superantigen SSA [Streptococcus pyogenes]

DNA sequence : 
ATGAATAAAAGAATAAGAATACTCGTTGTAGCATGTGTAGTTTTTTGTGCACAATTATTATCGATTAGTGTTTTTGCAAG
TAGTCAGCCTGACCCTACTCCAGAACAATTAAACAAATCTAGCCAATTTACTGGTGTTATGGGTAATTTGAGATGTTTAT
ATGATAACCATTTTGTAGAAGGGACTAATGTAAGATCCACAGGTCAGCTTTTACAGCATGATTTGATTTTTCCCATTAAG
GATTTGAAACTTAAAAACTATGATTCAGTAAAAACAGAGTTCAATAGTAAAGATTTAGCTGCAAAATATAAAAATAAAGA
TGTAGATATTTTTGGTTCCAATTACTACTATAACTGCTATTATTCGGAAGGAAATAGTTGTAAAAATGCCAAAAAAACTT
GTATGTACGGAGGTGTTACTGAGCACCATAGAAATCAAATTGAAGGTAAGTTCCCGAATATTACAGTAAAAGTTTATGAA
GATAATGAAAATATACTTTCGTTTGATATTACAACTAATAAAAAACAAGTCACTGTTCAAGAATTAGATTGTAAAACCAG
AAAAATATTAGTGTCTCGAAAAAATTTGTATGAGTTCAATAATTCTCCGTACGAGACAGGCTATATTAAATTTATAGAGA
GCTCAGGAGACAGTTTTTGGTACGATATGATGCCCGCACCTGGAGCAATATTTGATCAGTCTAAATACTTAATGCTATAT
AACGATAATAAGACAGTGAGCTCTTCAGCTATAGCTATAGAGGTTCACCTTACCAAAAAATAA

Protein sequence : 
MNKRIRILVVACVVFCAQLLSISVFASSQPDPTPEQLNKSSQFTGVMGNLRCLYDNHFVEGTNVRSTGQLLQHDLIFPIK
DLKLKNYDSVKTEFNSKDLAAKYKNKDVDIFGSNYYYNCYYSEGNSCKNAKKTCMYGGVTEHHRNQIEGKFPNITVKVYE
DNENILSFDITTNKKQVTVQELDCKTRKILVSRKNLYEFNNSPYETGYIKFIESSGDSFWYDMMPAPGAIFDQSKYLMLY
NDNKTVSSSAIAIEVHLTKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
seb AAL04126.1 Seb Virulence SaPI3 Protein 8e-70 59
seb YP_185778.1 enterotoxin B Virulence vSa1 Protein 1e-69 59
sec3 NP_372533.1 enterotoxin typeC3 Virulence vSa4 Protein 1e-72 58
sec3 NP_375118.1 enterotoxin C Virulence vSa4 Protein 1e-72 58
sec4 NP_645576.1 enterotoxin type C precursor Virulence vSa3 Protein 1e-72 57
sec-bov AAG29599.1 staphylococcal enterotoxin C-bovine Virulence SaPIbov Protein 3e-72 57
sec-bov YP_415865.1 enterotoxin C-bovine Not tested SaPIbov Protein 3e-72 57
sec-ov YP_005735946.1 staphylococcal enterotoxin C-ovine Virulence SaPI1 Protein 5e-70 56
SAMSHR1132_16730 YP_005326181.1 enterotoxin Virulence vSa¥â Protein 4e-62 54
unnamed AET14349.1 enterotoxin type C3 Virulence SaPI68111 Protein 2e-43 50
unnamed AAL26674.1 enterotoxin-like protein Virulence SCCcap1 Protein 5e-51 47
SAMSHR1132_16710 YP_005326179.1 enterotoxin Virulence vSa¥â Protein 2e-41 45
seg NP_372348.1 extracellular enterotoxin type G Virulence vSa¥â Protein 1e-42 45
seg NP_374931.1 extracellular enterotoxin type G Virulence vSa¥â Protein 1e-42 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ssa NP_664724.1 streptococcal superantigen SSA - phage associated VFG0954 Protein 1e-119 100
ssa NP_664724.1 streptococcal superantigen SSA - phage associated VFG1802 Protein 5e-70 59
ssa NP_664724.1 streptococcal superantigen SSA - phage associated VFG1804 Protein 5e-73 58
ssa NP_664724.1 streptococcal superantigen SSA - phage associated VFG1805 Protein 2e-72 56
ssa NP_664724.1 streptococcal superantigen SSA - phage associated VFG0951 Protein 2e-43 47