Gene Information

Name : fhuC.1 (SpyM3_0283)
Accession : NP_664087.1
Strain : Streptococcus pyogenes MGAS315
Genome accession: NC_004070
Putative virulence/resistance : Virulence
Product : ferrichrome ABC transporter ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 320068 - 320850 bp
Length : 783 bp
Strand : -
Note : best non-GAS blastp hit: gb|AAL40844.1|AF452237_1 (AF452237) FhuC [Streptococcus agalactiae]

DNA sequence : 
ATGACAACAATTAGTGCTGAAGACCTCACAATTGCCTATGAACAGCGTACCATCATCGATAAATTATCGTTTTATATTCC
TGAAGGTAAAATTACGACCATTATTGGCGCCAATGGCTGTGGGAAGTCTAGTTTATTAAAAGCACTGACAAGATTATTAC
CACCAAAACAGGGAGTTGTGTATTTAAATGGGCAAAACATTGCCACATTAGAAACTAAAGAGGTTGCTAAAAAACTAGCT
CTTTTACCTCAAGTTCAAGAAGCAACTAACGGCATAACTGTTTACGAATTGGTTTCTTACGGACGTTTTCCCCATCAATC
TTACTTTGGAAATCTTAGTCCAGCTGACAAAAAAGCCATTCATTGGGCTATGCAAGCCACCAATGTCATGGCCTATGCTG
ATCAACCTGTTGATGCTCTTTCTGGGGGGCAACGTCAAAGGGTTTGGCTTGCAATGGCATTAGCCCAAGGCACTGATACT
ATTTTTTTAGATGAGCCAACTACTTATTTAGATTTAAATCATCAACTAGAAATCCTAGAGCTCGTTAAATCCCTAAATAA
GGATGCCGGCAAGACTATTATTATGGTTCTTCACGACCTCAATCTTTCAGCCCGCTATTCGGATCATCTGATTGCTATGA
AACATGGCAAGATCCATTATACTGGTACTATAGCAGATGTTATGACTTCACCTATCATTCAAGACATCTTCCAAATCAAA
CCGGTACTGGTTGATGATCCTATCCACAACTGTCCTATAGTGCTGACTTATCAGCTTCAATAA

Protein sequence : 
MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSSLLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLA
LLPQVQEATNGITVYELVSYGRFPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIIMVLHDLNLSARYSDHLIAMKHGKIHYTGTIADVMTSPIIQDIFQIK
PVLVDDPIHNCPIVLTYQLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-58 47
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 3e-58 47
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 3e-58 47
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-58 47
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 7e-59 46
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 2e-53 45
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 2e-53 45
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 2e-52 44
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-50 44
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 7e-51 43
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 7e-51 43
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 7e-51 43
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 7e-51 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuC.1 NP_664087.1 ferrichrome ABC transporter ATP-binding protein BAC0164 Protein 1e-52 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuC.1 NP_664087.1 ferrichrome ABC transporter ATP-binding protein VFG0925 Protein 3e-58 46
fhuC.1 NP_664087.1 ferrichrome ABC transporter ATP-binding protein VFG1042 Protein 1e-52 44