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Name : polA.1 (SpyM3_0145) Accession : NP_663949.1 Strain : Streptococcus pyogenes MGAS315 Genome accession: NC_004070 Putative virulence/resistance : Unknown Product : DNA polymerase I Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0749 EC number : - Position : 172646 - 175288 bp Length : 2643 bp Strand : + Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair DNA sequence : ATGGAAAACAAGAATAAATTACTATTAATTGATGGGTCATCTGTTGCCTTTCGTGCCTTTTTTGCCCTTTACAATCAAAT TGACCGCTTTAAAAACCATAGCGGTCTTCATACCAATGCCATTTATGGCTTTCATCTGATGCTAGACCACATGATGAAAA GAGTCCAGCCTACTCACGTGCTGGTGGCTTTTGATGCGGGCAAAACCACCTTCCGAACAGAAATGTATGCCGATTATAAG GCGGGTCGCGCTAAAACCCCAGATGAATTTCGTGAGCAGTTTCCTTATATTCGTGAGATGTTGACAGCCCTTGGGATTGC TTATTATGAGTTGGAACACTACGAAGCAGACGATATTATCGGGACGCTTGATAAAATGGCGGAGCGCACAGAAGTGCCTT TTGATGTGACCATTGTCAGTGGTGATAAAGATTTGATCCAGTTAACTGATGAAAATACCGTGGTTGAAATTTCTAAAAAA GGGGTTGCCGAATTTGAAGAATTCACACCGGCTTACCTCATGGAAAAAATGGGCTTGACGCCAAACCAGTTTATTGACCT CAAAGCCTTGATGGGAGATAAATCGGATAACATTCCTGGAGTGACAAAAATTGGAGAAAAAACAGGCCTTAAGCTCCTTC ATAAATTTGGTAGTTTGGAAGGCATTTACGAGCATATTGATGGATTCAAGGCCTCAAAAATGAAAGAAAACTTGATCAAT GACCGTGACCAAGCTTTCCTATCTAAAACGCTCGCCACTATCAATACAGCATCTCCTATCACAATTGGCTTAGATGATAT TGTCTACAATGGTCCAGATGTTGCTAGCCTCTCTCAATTTTACGATGAGATGGATTTTGTGCAACTCAAGAAAGGTCTTG CTAGCCAGATGCCTCAAGAGCCAGTAGCTGCCATTTCCTATCAAGAAGTGACCAATGTGTCTGCTGATTTGTTTAGCGCA GAAGACATCTTCTACTTTGAAACGCTTCGGGACAATTACCATCGTGAGGCCATCATTGGTTTTGCTTGGGGACATGGTGA GCAGATTTACGCATCCACAGACCTTAGCCTATTAGCGACGGATAGTTTTAAGCAGGTCTTCCAAAAACCCATTGCCACTT ATGATTTTAAACGTAGCAAGGTCTTGTTGAGCCACTTAGGAATTGAGTTGGTAGCACCTAGCTATGATGCTAGATTAGCT AATTACCTTCTGTCAACTGTAGAAGACAATGAGCTTAGCACCATTGCCCGCATTTTTACTGACATCTCTTTGGAAGAAGA CGATACAGTCTATGGTAAAGGTGCTAAACGGGCTGTTCCTGATAAAGACGTTTTACTAGAACACTTAGCTCGTAAGGTCA AAGTATTATTAGATAGCAAGTCTCAAATGCTAGACAAGCTCACCGCCCATGAGCAACTAGACCTCTATCAGAATATTGAA TTGCCTTTGGCTAATGTCCTTGCTAAAATGGAAATTGAAGGGATCAAGGTTAATAGGGCGACTTTGCAAGATATGGCAGA GCAAAACAAGGTCATTATTGAAGCGCTCACCCAAGAGATTTATGATATGGCTGGCCAAGAATTTAACATTAATTCGCCTA AACAGCTGGGCAGTATCTTGTTTGAGAAGATGCAACTACCTCTTGAGATGACTAAGAAGACCAAAACAGGTTATTCTACA GCTGTTGATGTTTTGGAACGTTTGGCACCGATTGCTCCAATTGTGGCTAAAATTTTGGATTACCGCCAGATTACTAAATT GCAATCCACTTATGTGATTGGTTTACAGGATTATATTCTGGCTGATGGCAAGATTCATACCCGCTATGTGCAGGATCTCA CCCAGACAGGGCGTTTGTCTAGTGTGGACCCTAATCTTCAAAACATTCCCATTCGTTTGGAACAGGGGCGTTTGATTCGT AAGGCCTTTACCCCATCTCATGAAGATGCCGTCTTGTTGAGTTCAGATTACTCACAGATTGAATTGCGGGTACTGGCACA TATTTCAGGGGATGAGCATTTGATTGCTGCCTTTAATGAAGGGGCAGACATTCATACCTCAACGGCTATGCGTGTGTTTG GGATTGACAAGGCAGCAGATGTTACTGCCAATGACCGCCGTAATGCCAAGGCTGTTAACTTTGGAATTGTGTATGGGATT TCTGATTTTGGTTTGTCAAATAACCTTGGTATCACCCGTAAACAGGCCAAGTCTTACATTGATACCTATTTTGAACGCTA TCCTGGGATTAAAGCCTATATGGAAAATGTGGTGCGTGAGGCTAAAGACAAGGGCTATGTAGAGACCCTCTTTAAGCGTC GTCGTGAATTACCGGATATCAACTCTCGTAATTTCAACGTTCGCTCTTTTGCGGAGCGTACAGCCATCAACTCGCCCATT CAAGGAAGCGCAGCTGATATTCTCAAAATCGCTATGATTAATCTGGATAAGGCCTTGCAAGCAGGTGGTTTTAGAGCTAA AATGCTGCTTCAAGTGCATGATGAAATCGTTTTGGAAGTGCCAAATGATGAGTTGACTGCTATAAAAAAACTTGTCAAAG ATACCATGGAAGCTGCTGTTGATTTAGCAGTTCCTTTATGTGTCGATGAAAGTACTGGGCAGAGCTGGTACGAAGCCAAA TAA Protein sequence : MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYK AGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHKFGSLEGIYEHIDGFKASKMKENLIN DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSA EDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLA NYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYST AVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIR KAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPI QGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| polA | YP_281523.1 | DNA polymerase I | Not tested | Not named | Protein | 0.0 | 99 |
