Gene Information

Name : hasC (SpyM3_1853)
Accession : NP_665657.1
Strain : Streptococcus pyogenes MGAS315
Genome accession: NC_004070
Putative virulence/resistance : Virulence
Product : UDP-glucose pyrophosphorylase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1210
EC number : -
Position : 1883183 - 1884097 bp
Length : 915 bp
Strand : +
Note : best blastp hit: gb|AAA91810.1| (U33452) UDP-glucose pyrophosphorylase [Streptococcus pyogenes], and gb|AAL98669.1| (AE010124) UDP-glucose pyrophosphorylase [Streptococcus pyogenes MGAS8232]

DNA sequence : 
ATGACCAAAGTCAGAAAAGCCATTATTCCTGCTGCAGGTCTAGGAACACGTTTTTTACCTGCTACCAAAGCTCTTGCCAA
AGAGATGTTGCCCATCGTTGATAAGCCAACCATCCAGTTTATCGTCGAAGAAGCGCTAAAATCTGGCATCGAGGAAATCC
TTGTGGTGACCGGAAAAGCTAAACGCTCTATCGAGGACCATTTTGATTCAAACTTTGAATTAGAATACAACCTCCAAGCT
AAGGGGAAAAATGAACTGTTGAAATTAGTGGATGAAACCACTGCCATTAACCTTCATTTTATCCGTCAAAGCCACCCAAG
AGGACTGGGAGATGCTGTCTTACAAGCCAAAGCCTTTGTGGGCAATGAACCCTTTGTGGTCATGCTTGGAGATGACTTAA
TGGACATTACAAATGCATCCGCTAAACCTCTCACCAAACAACTCATGGAGGACTATGACAAGACGCATGCATCCACTATC
GCTGTGATGAAAGTTCCTCATGAAGATGTGTCTAGCTATGGGGTTATCGCTCCTCAAGGCAAGGCTGTCAAGGGTCTTTA
CAGTGTAGACACCTTTGTTGAAAAACCACAACCAGAAGATGCGCCTAGTGATTTGGCTATTATTGGTCGTTACCTCCTAA
CCCCTGAAATTTTTGATATTTTGGAAAGACAGGTCCCTGGAGCAGGTAACGAAGTGCAACTCACAGATGCTATCGATACC
CTCAATAAAACTCAGCGTGTCTTTGCACGAGAATTTAAAGGCAATCGTTACGATGTTGGGGATAAATTTGGATTCATGAA
AACATCTATCGACTATGCCTTAGAACACCCACAGGTCAAAGAGGACTTGAAAAATTACATTATCAAACTAGGAAAAGCTT
TGGAAAAAAGTAAAGTACCAACACATTCAAAGTAA

Protein sequence : 
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQA
KGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFDILERQVPGAGNEVQLTDAIDT
LNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEKSKVPTHSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0059 YP_300149.1 UTP-glucose-1-phosphate uridylyltransferase Not tested SCC15305cap Protein 7e-75 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasC NP_665657.1 UDP-glucose pyrophosphorylase VFG0964 Protein 3e-142 99