Gene Information

Name : purA (SpyM3_0125)
Accession : NP_663929.1
Strain : Streptococcus pyogenes MGAS315
Genome accession: NC_004070
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 147637 - 148929 bp
Length : 1293 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGACATCTGTAGTTGTTGTTGGTACCCAGTGGGGTGACGAAGGTAAAGGTAAAATCACTGATTTCTTGTCAGCGGATGC
AGAAGTAATTGCTCGCTATCAAGGTGGTGATAATGCTGGTCATACGATCGTGATTGATGGTAAGAAGTTTAAACTTCACT
TGATCCCATCAGGAATTTTCTTCCCGCAAAAAATTTCCGTTATTGGTAATGGTGTTGTGGTCAACCCCAAATCTTTGGTC
AAAGAGTTGGCGTACCTGCATGATGAAGGAGTGACGACAGATAACCTTCGCATTTCAGACCGAGCTCATGTCATTTTACC
TTATCATATCCAGCTGGATCAACTGCAAGAAGATGCAAAAGGTGACAATAAAATCGGAACAACTATTAAAGGGATTGGTC
CAGCTTATATGGATAAAGCTGCTCGAGTTGGTATCCGTATCGCAGATTTACTGGATAAGGATATCTTTGCAGAGCGCCTA
CGCATTAATTTAGCTGAGAAAAACCGTTTATTTGAGAAAATGTATAACAGTACACCTCTTGATTTTGATGCTATTTTTGA
AGAATACTATGCTTACGGTCAAGAAATCAAGCAATATGTGACAGATACTTCTGTAATTTTAAATGATGCACTTGATGCCG
GTAAACGTGTTCTTTTTGAAGGTGCACAAGGGGTTATGCTTGATATTGACCAAGGAACGTACCCATTTGTAACGTCTTCA
AACCCAGTTGCTGGTGGTGTAACCATTGGTTCTGGTGTTGGCCCAAGTAAAATCAACAAAGTAGTTGGTGTCTGTAAAGC
CTACACAAGCCGTGTCGGTGATGGGCCATTCCCTACAGAACTCTTTGATGAAGTGGGTGAGCGCATTCGTGAAGTGGGTC
ATGAGTACGGGACAACGACCGGCCGTCCACGTCGCGTGGGTTGGTTTGATTCGGTTGTCATGCGTCATAGTCGTCGTGTA
TCAGGTATTACTAACCTCTCTCTGAATTCCATTGACGTTCTTTCAGGGCTTGATACGGTTAAGATTTGTGTGGCTTATGA
CCTTGATGGGAAACGTATTGACTATTACCCAGCAAGTCTTGAACAACTCAAACGTTGCAAACCAATCTATGAAGAATTAC
CAGGCTGGCAAGAGGACATCACGGGTGTTCGTAGTCTTGATGAGCTGCCTGAAAATGCCCGCAACTATGTCCGTCGTGTT
GGAGAATTGGTTGGCGTTCGCATTTCAACCTTCTCAGTTGGTCCAGGACGTGAACAGACCAATATTCTTGAGTCGGTCTG
GGCATCTATCTAA

Protein sequence :
MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLV
KELAYLHDEGVTTDNLRISDRAHVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
RINLAEKNRLFEKMYNSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSS
NPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRV
SGITNLSLNSIDVLSGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPENARNYVRRV
GELVGVRISTFSVGPGREQTNILESVWASI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 0.0 99