Gene Information

Name : polA.2 (SpyM3_1443)
Accession : NP_665247.1
Strain : Streptococcus pyogenes MGAS315
Genome accession: NC_004070
Putative virulence/resistance : Unknown
Product : DNA polymerase A domain-containing protein
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 1441245 - 1443167 bp
Length : 1923 bp
Strand : -
Note : best blastp hit: gb|AAL82293.1| (AF424782) DNA polymerase A domain [Staphylococcus aureus phage phi 12]

DNA sequence :
ATGAGACATTTAAATATTGATATTGAAACCTATAGTTCGAATGACATCAAAAATGGGGTTTACAAGTACGCTGACGCAGA
AGATTTTGAGATTTTACTTTTCGCTTACTCTATAGATGGCGGAGAAGTAGAGTGCCTTGATTTGACAAGGCAGTCTCTAC
CTGAAGACATCAAAGATATGTTATTTGATGATAAAGTCCGAAAGCACGCCTTTAATGCCCAATTCGAAAGAGTTTGCCTC
AGTCGTTACCTCGGCCTACCTTACTATCTAGATCCTTGCCAATGGCAATGCACCATGGTGCTGGCCCAAGAGTTGGGTCT
GCCTTCAAGCTTGGAAAAGTGTGCGCTGTATTTAAAATTAGCGCAGGAAAAAGATACCTCGGGTAAAAACTTAATCAGAT
ACTTTTCCCTGCCTTGCAAACCAAGTAAAACTAACGGTGGGAGAACTAGAAATTTACCAGAACACGCCCCCGAAAAGTGG
CAAATGTTTATTGACTACTGCATCCAAGACGTTGTTGTTGAGATGGCAATCGCCGAAAAACTAGAGTCAGTTCCTGTGCA
CGACCGTGAATGGGATTACTACGCCTGTGACCAGAGAATCAACGACAGAGGCGTGGCGCTTGATAAAGAGTTAGTTGCTT
CGGCCTTGTATTGTAAAGATGTTAAGATGGAAAGTTTGTCTGGGGAACTAAAAGCTCTAACAGGACTTGATAATCCTAAT
AGCAGGACGCAGTTGCTACCGTGGCTAAAAGAACATGGCTATTCGGCTAGTGGGCTGACTAAAGCAGATGTTGAGAAGGA
GCTTAAGACGGCCGAAGGAGAACTTAAGAGAGTTTTAGAACTTAAACTACAAACCGCTATGTCAAGTCTAAAAAAATATG
AAGCTATGGAAAGAGCTAGGTGCTCAGACGGACGAGTTCATGGGCTACTTCAGTTTTACGGGGCTAGCCGGACAGGAAGA
TGGGCGGGCAGAGTTGTCCAAGTACAGAACTTAGCTAGGAATTATATAAAGGATCTAGATGATGCTAGAGAGTATGTTAA
AAAGCGTGACATTGATGCTGTGGAGATTTTATACGATAGCCTTAATGACACTTTAAAGCAGCTCGTGCGAACGGCCCTCG
TGGCTAAAGATGGCTGTACCTTCTATGTCTCTGACTTCTCGGCGATTGAGGCTAGGGTGATTGCGTGGTTTGCTGGAGAG
CAGTGGAGGCTTGACGTGTTTTCGACGCACGGGAAAATCTACGAGGCGTCTGCCAGTCAGATGTTCGGAATTCCAATTGA
GGAGATTGACAAGGAACTACGCCAAAAGGGCAAAATTTCAGAGTTAGCACTTGGCTATCAAGGGGGTCCTGGAGCGCTTA
AGCAGATGGGGGCTCTAAACATGGGAGTCAAAGAAGAAGAGCTTCAAGGGTTAGTTGATGACTGGCGCAGGGCCAATAAG
AAAATCGTCCAATTTTGGAAAGACGTACAAAGAGCCGCCATCAAAGCCATCAAATCGAGAGCACCTGTAAGACTTGGGAA
GCTACGATTTAGATACCGTAAAGGTTTCCTCTTTATAACATTGCCTAGCGGTAGGAACTTAGCTTATGCAAGAGCCAAGG
TTGAGCCGGGCGACTATGGAGACAAAATCGTCTATGAGGGCCAAGGAGATAAGGCCTACTTCACAGCGCAAGAGACTTAC
GGAGGTAAGCTTGTCGAAAATATCGTTCAGGCGACAGCTAGGGATATTCTAGCCGAAGCGCTTCTGAGAATTGAAGCTGC
CGGCCATGGTGTTGTTTTCCACGTTCATGACGAGGCTATTATCGAAGGCTCAGGCCTGACAATCGAAGAGGTTAATGATT
TGATGGCTCAGGCCCCTGAATGGGCGGAGGGTCTTCCTTTAAATAGCGAAGGCTACATAACAAAGTATTATATGAAGGAT
TAG

Protein sequence :
MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVECLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCL
SRYLGLPYYLDPCQWQCTMVLAQELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKTNGGRTRNLPEHAPEKW
QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYCKDVKMESLSGELKALTGLDNPN
SRTQLLPWLKEHGYSASGLTKADVEKELKTAEGELKRVLELKLQTAMSSLKKYEAMERARCSDGRVHGLLQFYGASRTGR
WAGRVVQVQNLARNYIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGCTFYVSDFSAIEARVIAWFAGE
QWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGPGALKQMGALNMGVKEEELQGLVDDWRRANK
KIVQFWKDVQRAAIKAIKSRAPVRLGKLRFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIVYEGQGDKAYFTAQETY
GGKLVENIVQATARDILAEALLRIEAAGHGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEGLPLNSEGYITKYYMKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 0.0 99
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 3e-156 55
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 4e-157 55