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Name : speA3 (SpyM3_1301) Accession : NP_665105.1 Strain : Streptococcus pyogenes MGAS315 Genome accession: NC_004070 Putative virulence/resistance : Virulence Product : exotoxin type A precursor - phage associated Function : - COG functional category : - COG ID : - EC number : - Position : 1313684 - 1314439 bp Length : 756 bp Strand : + Note : best non-GAS blastp hit: pir||S18783 exotoxin type A precursor (allele 3) - Streptococcus pyogenes phage (strain MGAS158 isolate Nebraska and others) (fragment), and pir||S18798 exotoxin A precursor (allele 3) - Streptococcus pyogenes (strain MGAS495 isol DNA sequence : ATGGAAAACAATAAAAAAGTATTGAAGAAAATGGTATTTTTTGTTTTAGTGACATTTCTTGGACTAACAATCTCGCAAGA GGTATTTGCTCAACAAGACCCCGATCCAAGCCAACTTCACAGATCTAGTTTAGTTAAAAACCTTCAAAATATATATTTTC TTTATGAGGGTGACCCTGTTACTCACGAGAATGTGAAATCTGTTGATCAACTTTTATCTCACGATTTAATATATAATGTT TCAGGGCCAAATTATGATAAATTAAAAACTGAACTTAAGAACCAAGAGATGGCAACTTTATTTAAGGATAAAAACATTGA TATTTATGGTGTAGAATATTACCATCTCTGTTATTTATGTGAAAATGCAGAAAGGAGTGCATGTATCTACGGAGGGGTAA CAAATCATGAAGGGAATCATTTAGAAATTCCTAAAAAGATAGTCGTTAAAGTATCAATCGATGGTATCCAAAGCCTATCA TTTGATATTGAAACAAATAAAAAAATGGTAACTGCTCAAGAATTAGACTATAAAGTTAGAAAATATCTTACAGATAATAA GCAACTATATACTAATGGACCTTCTAAATATGAAACTGGATATATAAAGTTCATACCTAAGAATAAAGAAAGTTTTTGGT TTGATTTTTTCCCTGAACCAGAATTTACTCAATCTAAATATCTTATGATATATAAAGATAATGAAACGCTTGACTCAAAC ACAAGCCAAATTGAAGTCTACCTAACAACCAAGTAA Protein sequence : MENNKKVLKKMVFFVLVTFLGLTISQEVFAQQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNV SGPNYDKLKTELKNQEMATLFKDKNIDIYGVEYYHLCYLCENAERSACIYGGVTNHEGNHLEIPKKIVVKVSIDGIQSLS FDIETNKKMVTAQELDYKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMIYKDNETLDSN TSQIEVYLTTK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| seb | YP_185778.1 | enterotoxin B | Virulence | vSa1 | Protein | 2e-47 | 49 |
| seb | AAL04126.1 | Seb | Virulence | SaPI3 | Protein | 1e-47 | 49 |
| sec4 | NP_645576.1 | enterotoxin type C precursor | Virulence | vSa3 | Protein | 3e-47 | 47 |
| sec3 | NP_372533.1 | enterotoxin typeC3 | Virulence | vSa4 | Protein | 3e-47 | 47 |
| sec3 | NP_375118.1 | enterotoxin C | Virulence | vSa4 | Protein | 3e-47 | 47 |
| sec-bov | AAG29599.1 | staphylococcal enterotoxin C-bovine | Virulence | SaPIbov | Protein | 5e-47 | 47 |
| sec-bov | YP_415865.1 | enterotoxin C-bovine | Not tested | SaPIbov | Protein | 7e-47 | 47 |
| sec-ov | YP_005735946.1 | staphylococcal enterotoxin C-ovine | Virulence | SaPI1 | Protein | 2e-45 | 46 |
| seg | NP_372348.1 | extracellular enterotoxin type G | Virulence | vSa¥â | Protein | 1e-38 | 45 |
| seg | NP_374931.1 | extracellular enterotoxin type G | Virulence | vSa¥â | Protein | 1e-38 | 45 |
| unnamed | AAL26674.1 | enterotoxin-like protein | Virulence | SCCcap1 | Protein | 2e-46 | 45 |
| SAMSHR1132_16710 | YP_005326179.1 | enterotoxin | Virulence | vSa¥â | Protein | 3e-38 | 44 |
| SAMSHR1132_16730 | YP_005326181.1 | enterotoxin | Virulence | vSa¥â | Protein | 4e-43 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| speA3 | NP_665105.1 | exotoxin type A precursor - phage associated | VFG0951 | Protein | 1e-105 | 100 |
| speA3 | NP_665105.1 | exotoxin type A precursor - phage associated | VFG1802 | Protein | 9e-48 | 49 |
| speA3 | NP_665105.1 | exotoxin type A precursor - phage associated | VFG1805 | Protein | 9e-47 | 47 |
| speA3 | NP_665105.1 | exotoxin type A precursor - phage associated | VFG1804 | Protein | 1e-47 | 47 |
| speA3 | NP_665105.1 | exotoxin type A precursor - phage associated | VFG0954 | Protein | 2e-38 | 46 |
