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Name : nrdF (SpyM3_1050) Accession : NP_664854.1 Strain : Streptococcus pyogenes MGAS315 Genome accession: NC_004070 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit beta Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0208 EC number : 1.17.4.1 Position : 1092824 - 1093783 bp Length : 960 bp Strand : + Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE DNA sequence : ATGACTACATATTATGAAGCAATTAACTGGAATGAAATCGAAGACGTCATTGACAAGTCAACTTGGGAAAAGTTGACCGA ACAATTTTGGCTTGATACCCGTATCCCTTTATCAAATGACTTAGACGATTGGCGCAAACTTTCTCTTCAAGAAAAAGATC TTGTTGGCAAGGTTTTTGGAGGATTAACCCTACTTGATACCATGCAATCAGAAACTGGTGTCGAAGCTATTCGTGCTGAT GTTCGCACTCCTCACGAAGAAGCTGTCTTAAACAATATTCAATTCATGGAATCAGTTCACGCTAAATCTTATTCGTCTAT CTTTTCAACCTTAAACACAAAAAAAGAAATTGAAGAGATCTTTGAGTGGACTAATAATAATGAGTTTCTTCAAGAAAAAG CACGTATTATCAATGACATTTACGCTAATGGAGATGCCTTACAAAAGAAAGTTGCCTCAACATATCTCGAAACTTTCCTT TTTTATTCTGGCTTTTTCACCCCTCTTTACTATTTGGGAAATAATAAGCTAGCAAATGTTGCTGAAATCATTAAACTAAT TATTCGTGATGAATCTGTACATGGTACTTATATCGGTTACAAATTCCAGCTTGGTTTTAACGAACTACCAGAAGATGAGC AAGAGAATTTTCGTGATTGGATGTATGACCTCCTTTATCAGCTGTATGAAAATGAAGAAAAATACACCAAAACGCTTTAT GATGGCGTGGGGTGGACTGAGGAAGTTATGACCTTTTTACGCTACAATGCTAACAAAGCTCTTATGAATTTAGGACAAGA TCCTTTATTCCCAGATACTGCAAACGATGTTAACCCAATTGTTATGAATGGTATTTCAACAGGAACATCAAACCATGACT TTTTCTCACAGGTAGGGAATGGCTATCTTCTTGGTTCTGTAGAAGCTATGTCTGATGACGATTATAATTATGGACTCTAA Protein sequence : MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRAD VRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLY DGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1479 | YP_001800873.1 | ribonucleoside-diphosphate reductase subunit beta | Not tested | Not named | Protein | 1e-73 | 49 |
