Gene Information

Name : nrdF (SpyM3_1050)
Accession : NP_664854.1
Strain : Streptococcus pyogenes MGAS315
Genome accession: NC_004070
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1092824 - 1093783 bp
Length : 960 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACTACATATTATGAAGCAATTAACTGGAATGAAATCGAAGACGTCATTGACAAGTCAACTTGGGAAAAGTTGACCGA
ACAATTTTGGCTTGATACCCGTATCCCTTTATCAAATGACTTAGACGATTGGCGCAAACTTTCTCTTCAAGAAAAAGATC
TTGTTGGCAAGGTTTTTGGAGGATTAACCCTACTTGATACCATGCAATCAGAAACTGGTGTCGAAGCTATTCGTGCTGAT
GTTCGCACTCCTCACGAAGAAGCTGTCTTAAACAATATTCAATTCATGGAATCAGTTCACGCTAAATCTTATTCGTCTAT
CTTTTCAACCTTAAACACAAAAAAAGAAATTGAAGAGATCTTTGAGTGGACTAATAATAATGAGTTTCTTCAAGAAAAAG
CACGTATTATCAATGACATTTACGCTAATGGAGATGCCTTACAAAAGAAAGTTGCCTCAACATATCTCGAAACTTTCCTT
TTTTATTCTGGCTTTTTCACCCCTCTTTACTATTTGGGAAATAATAAGCTAGCAAATGTTGCTGAAATCATTAAACTAAT
TATTCGTGATGAATCTGTACATGGTACTTATATCGGTTACAAATTCCAGCTTGGTTTTAACGAACTACCAGAAGATGAGC
AAGAGAATTTTCGTGATTGGATGTATGACCTCCTTTATCAGCTGTATGAAAATGAAGAAAAATACACCAAAACGCTTTAT
GATGGCGTGGGGTGGACTGAGGAAGTTATGACCTTTTTACGCTACAATGCTAACAAAGCTCTTATGAATTTAGGACAAGA
TCCTTTATTCCCAGATACTGCAAACGATGTTAACCCAATTGTTATGAATGGTATTTCAACAGGAACATCAAACCATGACT
TTTTCTCACAGGTAGGGAATGGCTATCTTCTTGGTTCTGTAGAAGCTATGTCTGATGACGATTATAATTATGGACTCTAA

Protein sequence :
MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRAD
VRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLY
DGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 1e-73 49