Gene Information

Name : thyA (BUsg425)
Accession : NP_660757.1
Strain : Buchnera aphidicola Sg
Genome accession: NC_004061
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 481374 - 482168 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAATATTTAGATTTAATAAAAAAAATAATTAAAAATGGAAATTCAAAAAAAGATCGAACCGGTACAGGAACTTT
ATCTATTTTTGGACATCATATGAAATTTGATTTAAAAAAAGGTTTTCCTCTTATCACAACAAAAAAATGTCATATACCAT
CAATTATTCATGAACTTTTATGGTTTCTTAGGGGAGAAACAAATATTAAATATCTTAACGAAAATAAAATATCAATTTGG
GATAACTGGGCAGATAAATTTGGTGATCTAGGTCCAATTTATGGAAAACAATGGAGAAGTTGGGATACATCTAACGGAAA
AAAAATCGATCAAATAAAAAACGTACTAAAACAAATAAAAGAAGATCCTGATTCACGTAGAATTTTAGTATCTAGTTGGA
ACGTTGGAGAAATTGATAAAATGTCTTTAGCTCCATGTCATATATTATTTCAATTTTACGTATTAAAAAAAAAATTAAGT
TGTCAACTTTACCAACGTTCTTGCGATGTATTTCTTGGTTTGCCTTTTAATATAGCTAGCTATGCAATACTGATACATAT
GATAGCTCAACAATGTAATCTACAAGTTGGAGAATTTTTATGGACAGGAGGTGACGTTCATTTATATAAAAATCATGTTG
AATTGGCGAAAAAACAAATATTGAGAATACCTAAAAAATTACCAGAGTTAATAATTTTAAAAAAACCTCAATCATTATTT
CAATATTCTTTTGAAGATTTTAAAATTGTTGGGTATAAACCATATTCCTTAATTAAGGGAAAAATATCTGTATAA

Protein sequence :
MKQYLDLIKKIIKNGNSKKDRTGTGTLSIFGHHMKFDLKKGFPLITTKKCHIPSIIHELLWFLRGETNIKYLNENKISIW
DNWADKFGDLGPIYGKQWRSWDTSNGKKIDQIKNVLKQIKEDPDSRRILVSSWNVGEIDKMSLAPCHILFQFYVLKKKLS
CQLYQRSCDVFLGLPFNIASYAILIHMIAQQCNLQVGEFLWTGGDVHLYKNHVELAKKQILRIPKKLPELIILKKPQSLF
QYSFEDFKIVGYKPYSLIKGKISV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 3e-71 55