Gene Information

Name : serS (BUsg303)
Accession : NP_660646.1
Strain : Buchnera aphidicola Sg
Genome accession: NC_004061
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 346910 - 348193 bp
Length : 1284 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAAATCCTTATTTATTACGTAACCAAATAGATGCAATATCAAAAAAATTATTAAAAAAAAAATTTAAATTAGATAT
ATCACTAATATCTTCTTTAGAAAAAAAACGGAAAAAATTGCAAATTAAAACAGACAATTTGCAATACAAGCACAATACTT
TATCAGCGTTATTTAAAAAAGAAAAAAAAATTCAAGAATTAGATGAAAATTTAAAAAGAACACTTACCAAATCTAGTAAA
AATTTATCTGAATTAAAAATTGAACTCAATCTATTACAAGAAAAAATTCATAATTTTTCTTTATCTATACCTAATATTCC
TTCTGATGATGTTCCAGAAGGAAATTCATCAGAAAACAATAAAATTGTAAAATATTGGGGTAAAAAAAGGGAATATAGTT
TTGCAGTTCGAGATCATGTAGAAATAGGAAATAAATTGAATCAATTAGATTGGAAATCTTCAGCAAAAATATCAGGTGCA
CGATTTATTGTTATGAAAGGAAATATAGCTCTTTTACATCGTGCATTAAGTCAATTTATGTTAGATTTACATACTATAAA
GCATGGGTATACAGAAACTTATGTACCTTATTTAGTAAATCATGATTCGCTATACGGAACAGGGCAATTACCAAAATTTA
CTGATGATTTATTTCATATAAATTCTATTGATAAAAAAAAATATGTATTAATTCCGACAGCTGAAGTACCATTAACGAAT
TTGTTTTCTAATCAGATATTAAATGAAACAGAACTGCCTATTATGTTAACTGCTCATACTCCTTGTTTTCGATCTGAAGC
TTCTTCTTATGGACGTGATAGTAAGGGATTAATTCGATTACATCAATTTGATAAAGTAGAACTTGTGCAAATTATACAAC
CTGAATTGTCTATGAATGCTTTAGAGTTGTTAACTCATCATGCAGAAAAAGTTCTACAACTTTTAGAATTACCATATAGA
AAGGTACTTTTATGTGGAGGAGAAATGGGTTTTTCTGCAACTAAAACATATGATTTAGAAGTATGGTTTCCTTCTCAGAA
AAAATACAGAGAAATTTCTTCGTGTTCTAATATGAGCGACTTTCAAGCTCGTCGTATGAAAACTCGTTATAAGAAAAAAA
AGGAAAAAAGTAACAGTTTTGTTCATACATTAAATGGTTCAGGTTTAGCAATTGGTAGAACATTAGCTGCTATATTAGAA
AATTATCAAGATAGTGATGGTCGAGTTACTATTCCAAAAATTTTACAAAAAAAATATATGCAAGGTATAGAATATATAAA
TTAA

Protein sequence :
MLNPYLLRNQIDAISKKLLKKKFKLDISLISSLEKKRKKLQIKTDNLQYKHNTLSALFKKEKKIQELDENLKRTLTKSSK
NLSELKIELNLLQEKIHNFSLSIPNIPSDDVPEGNSSENNKIVKYWGKKREYSFAVRDHVEIGNKLNQLDWKSSAKISGA
RFIVMKGNIALLHRALSQFMLDLHTIKHGYTETYVPYLVNHDSLYGTGQLPKFTDDLFHINSIDKKKYVLIPTAEVPLTN
LFSNQILNETELPIMLTAHTPCFRSEASSYGRDSKGLIRLHQFDKVELVQIIQPELSMNALELLTHHAEKVLQLLELPYR
KVLLCGGEMGFSATKTYDLEVWFPSQKKYREISSCSNMSDFQARRMKTRYKKKKEKSNSFVHTLNGSGLAIGRTLAAILE
NYQDSDGRVTIPKILQKKYMQGIEYIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-90 51