Gene Information

Name : spH (BA_0678)
Accession : NP_843205.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Virulence
Product : sphingomyelinase C
Function : -
COG functional category : R : General function prediction only
COG ID : COG3568
EC number : -
Position : 696054 - 697070 bp
Length : 1017 bp
Strand : +
Note : 'similar to GB:Z22651, GB:L04696, GB:M63454, GB:L04695, GB:L11604, GB:L11666, GB:L19937, GB:L22027, GB:L32862, GB:M32319, GB:M33573, GB:M58636, GB:M75138, GB:M81798, GB:M84381, GB:M84385, GB:U03859, GB:U06862, GB:U11265, GB:U17107, GB:U30904, GB:X61708, G

DNA sequence :
ATGGAGGTATGGAACGTGAAAGGTAAATTGCTAAAAGGTGTACTTAGCTTTGGGATTGGTTTAGGAGTTTTATACGGAGG
ATCCTCAGCTCAAGCAGATACGTCTACAGATCAAAACAATACTTTGAAAGTGATGACGCATAACGTGTACATGCTATCAA
CTAACTTATATCCGAATTGGGGACAAAGTGAGCGTGCTGATTTAATTGGGGCGGCAGATTATATTAAGAATCAAGACGTT
GTTATATTAAATGAAGTGTTTGATAATAGTGCTTCAGATCGCCTTTTAGGAAATTTGAAGAAAGAATACCCAAATCAAAC
AGCTGTATTAGGTCGTAGCAACGGAAATGAATGGGATAAAACGTTAGGTAGCTATTCATCTGCAACTCCTGAAGATGGAG
GCGTTGCAATCGTTAGCAAATGGCCGATCGTTGAAAAGGTTCAATATGTATTTGCAAATGGATGTGGACCAGATAATTTA
TCGAATAAAGGATTTGTATACACGAAAATTAAGAAAAATGATCGTTTCGTTCATGTAATTGGGACGCATTTGCAGGCTGA
AGATAGTATGTGCGGAAAAACTTCACCTGCATCTGTACGTACAAACCAGTTAAAAGAAATTCAAGATTTTATTAAAAATA
AAAATATACCAAATGACGAGTACGTCCTATTTGGTGGTGATATGAATGTGAATAAAATAAATGCTGAGAACAATAGTGAC
TCAGAATACGCATCAATGTTCAAAACATTGCACGCTTCTATTCCATCTTATACAGGACATACAGCAACTTGGGATGCAAC
GACAAACAGTATTGCAAAATATAATTTCCCTGATAGCCCTGCCGAGTATTTAGATTATATTATTGCAAGTAAGGACCATG
CGAATCCGTCATTTATAGAGAATAAAGTATTACAACCGAAATCTCCACAGTGGACTGTTACATCATGGCTCAAAAAATAT
ACATATAATGATTATTCTGATCATTATCCAGTCGAGGCGACTATTTCTATGAAGTAG

Protein sequence :
MEVWNVKGKLLKGVLSFGIGLGVLYGGSSAQADTSTDQNNTLKVMTHNVYMLSTNLYPNWGQSERADLIGAADYIKNQDV
VILNEVFDNSASDRLLGNLKKEYPNQTAVLGRSNGNEWDKTLGSYSSATPEDGGVAIVSKWPIVEKVQYVFANGCGPDNL
SNKGFVYTKIKKNDRFVHVIGTHLQAEDSMCGKTSPASVRTNQLKEIQDFIKNKNIPNDEYVLFGGDMNVNKINAENNSD
SEYASMFKTLHASIPSYTGHTATWDATTNSIAKYNFPDSPAEYLDYIIASKDHANPSFIENKVLQPKSPQWTVTSWLKKY
TYNDYSDHYPVEATISMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 5e-71 59
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 6e-71 59
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 4e-71 59
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 2e-76 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spH NP_843205.1 sphingomyelinase C VFG1798 Protein 2e-78 58
spH NP_843205.1 sphingomyelinase C VFG0674 Protein 9e-77 55