Gene Information

Name : thiC (BA_5463)
Accession : NP_847631.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4951514 - 4953274 bp
Length : 1761 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAAACAGTCTGTTTCAGCTGAGCAAATTGAATTGAAATCGAGTTTACCAGGAAGTAAGAAAGTGTATGTGGATGGACC
ACGAGAAGGTATGAAAGTGCCGATGCGTGAGATTGAACAAAGTGATACAAATGGCGTTCCAAATCCGCCAATTCGTGTGT
ATGATACAAGCGGTCCTTACACAGATCCTGCGTATAAAGTCGAGTTAGAGAAGGGGATTCCAACGCCGCGCCACTCTTGG
ATTCTAGAGCGCGGAGATGTAGAGGCATACGAAGGGCGCGAAGTGAAACCAGAGGATGACGGTGTGAAGGTGGCTTCGAA
ACATACACCTGTTTTCCCGCAAATGGATCGCAAACCGCTTAGAGCGAAGCAAGGTGCAAATGTTACGCAAATGCATTATG
CACGTAATGGCATCATTAAGTCTGAGATGGAATATGTTGCGATTCGTGAAGGAGTAGACCCGGAATTTGTTCGTAAGGAA
ATCGCGGAAGGTCGCGCTATTTTACCAGCGAATATTAACCATCCTGAAGCAGAACCGATGATTATTGGGCGTAATTTCCA
TGTGAAGGTTAATGCGAATATCGGAAACTCTGCTGTATCTTCTTCTATTGCAGAAGAAGTAGAGAAGATGACGTGGGCAA
CTCGCTGGGGTGCAGATACGATTATGGATTTATCTACAGGTAAAAACATTCATACGACGCGCGAGTGGATTATTCGTAAC
GCACCTGTACCAGTTGGAACTGTACCAATCTATCAAGCACTGGAAAAAGTAAACGGAATTGCAGAAGATTTAACGTGGGA
AGTGTATCGTGATACGTTAATTGAGCAAGCGGAGCAAGGCGTAGATTACTTTACGATTCACGCTGGCGTATTACTTCGTT
ACATTCCAATTACGGCGAAACGTACGACAGGTATCGTTTCACGCGGTGGTTCAATTATGGCACAGTGGTGTTTATTCCAT
CATAAAGAAAACTTCCTATACACTCATTTTGAAGAGATTTGTGAAATTATGAAGCAGTACGATGTTTCGTTCTCTCTTGG
AGATGGATTACGTCCAGGTTCGATTGCAGATGCAAATGACGAAGCACAGTTTTCTGAGCTTGAAACACTTGGTGAATTAA
CGAAGATTGCTTGGAAACATGATGTGCAAGTGATGATTGAAGGGCCTGGGCATGTACCGATGCATTTAATTAAAGAGAAT
ATGGAGAAAGAACTTGATATTTGTCAGGGCGCGCCGTTCTATACACTTGGGCCGTTAACGACAGATATTGCACCAGGTTA
TGACCATATTACATCTGCGATTGGAGCTGCGATGATTGGTTGGTTTGGAACGGCGATGCTTTGTTATGTAACGCCGAAAG
AACATTTAGGTTTACCAAATAAAGATGATGTTCGAGAAGGTGTTATTACGTACAAAATCGCTGCACATGCGGCTGATCTA
GCGAAAGGTCACAAAACGGCTCATCAGCGTGATGATGCCCTTTCAAAAGCACGCTTTGAATTCCGTTGGCGCGATCAATT
TAATTTATCTTTAGATCCTGAACGCGCGATGGAGTATCACGATGAAACATTGCCAGCAGAAGGAGCGAAAACGGCTCATT
TCTGTTCCATGTGTGGACCGAAGTTTTGTAGTATGAGAATTTCACATGATATTCGTGAATACGCAAAAGAAAATGATTTA
GAAACGACAGAAGCAATTGAAAAAGGAATGAAAGAGAAAGCGAAAGAATTTAAAGAAACTGGTAGTCATTTATACCAATA
A

Protein sequence :
MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSW
ILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIIKSEMEYVAIREGVDPEFVRKE
IAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRN
APVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFH
HKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKEN
MEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADL
AKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDL
ETTEAIEKGMKEKAKEFKETGSHLYQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 66