Gene Information

Name : leuS (BA_4991)
Accession : NP_847185.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 4528353 - 4530761 bp
Length : 2409 bp
Strand : -
Note : 'leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucy

DNA sequence :
ATGAGCTTTAATCATCAAGAAATTGAGAAGAAGTGGCAAGGGTACTGGGAAGAGAATAAAACATTCCGTACGCCAGATGA
GACAGAAAAACCAAAATTTTATGCACTAGATATGTTCCCATATCCATCAGGTGCAGGCCTACACGTAGGACATCCAGAAG
GTTATACAGCAACGGATATTTTATCTCGTATGAAGCGTATGCAAGGGTATAACGTTCTTCATCCAATGGGATGGGATGCA
TTCGGTCTTCCAGCAGAGCAATATGCACTTGATACTGGAAACAGCCCGGCTGAATTTACAGAGCATAATATTAATACGTT
CCGTAACCAAATTAAATCATTAGGTTTCTCTTACGATTGGGACCGTGAAGTAAATACAACAGATCCAAACTACTACAAGT
GGACACAATGGATCTTCCTAAAACTATTTGAAAAAGGCTTAGCTTACGTTGATGAAGTACCTGTAAACTGGTGCCCAGCA
CTTGGTACAGTACTTGCAAACGAAGAAATCATTGACGGTAAGAGTGAGCGCGGTGGACATCCAGTTGAGCGTCGTCCGAT
GAGACAGTGGATGTTAAAAATTACAGCTTACGGAGATCGTCTATTAGAAGATCTAGACGAGCTTGATTGGCCAGAAAGCT
TAAAAGATATGCAACGTAACTGGATCGGTCGTTCTGAAGGTGCAGAAGTACACTTCAACATCGACGGTACAGATGAGAAG
TTCACAGTTTTCACAACGCGCCCTGATACACTATTTGGTGCAAGCTACTGTGTACTTGCTCCGGAACATGCGCTTGTTGC
TGACATTACAACTGCTGATCAAAAAGAAGCTGTAGAAGCTTACATTAATTCTGTAAAAATGAAGAGTGATCTAGAGCGTA
CAGAACTTGCGAAAGAGAAAACTGGTGTATTCACTGGTGCTTATGCAGTTAACCCAGTAAATGGTGAGAAATTACCAATC
TGGATCGCTGATTACGTTCTTGCAACTTACGGAACAGGTGCTGTAATGGCGGTTCCAGCTCACGATGAGCGTGACTATGA
ATTTGCATCAACGTTCAATCTTCCAATGAAGGAAGTTGTAAAAGGTGGAGATATTACGAAAGAAGCATACACAGGTGATG
GTGCTCACGTAAACTCAGCATTCCTTGATGGTTTAAATAAAGAAGAAGCAATCGCAAAAATGATTGAATGGCTTGAAGTA
ACGAGCGCAGGAAATCAAAAAGTAACATACCGTCTACGTGACTGGTTATTCAGCCGTCAACGTTACTGGGGTGAGCCAAT
TCCAGTAATTCACTGGGAAGATGGCACAATGACAGCTGTGAAAGAAGAAGAATTACCATTAGTTCTTCCGAAAACAGAAA
ACATCCGTCCTTCAGGTACAGGTGAATCACCACTTGCTAACATTGACGAGTGGGTAAATGTTGTTGATCCTGAGACTGGT
AAAAAAGGTCGTCGTGAAACAAATACAATGCCGCAATGGGCTGGTAGCTGCTGGTATTACCTACGTTACATCGATCCAAA
CAACAGCGAAGCACTTGTAGATCCTGAAAAAGTAAAACAATGGCTTCCAGTTGATATTTATATCGGTGGTGCAGAACACG
CTGTACTTCACTTACTATATGCTCGTTTCTGGCATAAAGTATTATACGATATCGGTGTAGTTCCAACGAAAGAGCCGTTC
CAACAATTATTCAACCAAGGTATGATTCTAGGTGAAAACAACGAGAAAATGAGTAAATCAAAAGGTAACGTTGTAAACCC
TGATGATATCGTAGCAAGCCACGGTGCAGATACACTTCGTCTATACGAAATGTTCATGGGACCATTAGATGCTTCAATCG
CTTGGTCTGAAAATGGTCTTGATGGAGCACGTCGTTTCCTAGATCGCGTATGGCGCCTATTCGTTCAAGATAACGGTGAA
TTAAGTGAGAAAATTACTGATGCACCAAATAAAGATCTTGAAAAAGCTTACCACCAAACAGTCAAGAAAGTAACAGAAGA
CTATGCAGAGCTTCGCTTCAACACAGCGATTTCTCAAATGATGGTGTTCATCAACGATGCATACAAAGCTGAAACACTTC
CGAAAGAATATGTAGAAGGTTTCGTAAAAATGATTGCACCAGTTGCACCTCACATCGGGGAAGAGCTATGGAGCAAACTT
GGATACAATGAAACAATCACATATGCAAGCTGGCCAACATTTGATGAGTCTAAACTTGTAGAAGATGAAGTTGAAATCGT
TGTTCAAGTTATGGGTAAAGTTCGCGCAAAACTAACAATGAGTAAAGACGCATCAAAAGACGAAATGGAAAAACTTGCAC
TTGAAGCAATTCAAGACCAAATCGAAGGAAAAACAGTTCGTAAAGTAATTGTAGTTCCTGGAAAACTTGTTAACGTTGTT
GCAAACTAA

Protein sequence :
MSFNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPA
LGTVLANEEIIDGKSERGGHPVERRPMRQWMLKITAYGDRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDEK
FTVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKTGVFTGAYAVNPVNGEKLPI
WIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVKGGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEV
TSAGNQKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETG
KKGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPF
QQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQDNGE
LSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAYKAETLPKEYVEGFVKMIAPVAPHIGEELWSKL
GYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLTMSKDASKDEMEKLALEAIQDQIEGKTVRKVIVVPGKLVNVV
AN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 67