Gene Information

Name : metC-2 (BA_4481)
Accession : NP_846706.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 4075596 - 4076759 bp
Length : 1164 bp
Strand : +
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAGTTATTCTATAGATACACTCTTACTACACAACCAATATAAACATGATCCACAAACAGGAGCTGTTAACGTTCCCAT
CTATAACACATCAACATTCCACCAGTTCGATGTAGATACGTTCGGGAAATATGACTATAGCAGGTCAGGAAATCCAACTC
GTGAAGCTCTTGAAGACATCATTGCTTTATTAGAAGGCGGAACGAAAGGATTTGCCTTCGCATCAGGAATTGCAGCGATT
TCTACTGCATTCCTCCTTCTTTCACAAGGTGATCACGTACTCATTTCAGAAGACGTATACGGAGGGACTTATCGAATAAT
AACTGAAGTTCTCTCCCGTTATGGTGTTTCACATACATTTGTTGATATGACCAATCTAGAAGAAATCAAGCAAAATATAA
AACAAAATACAAAGCTCTTTTATGTAGAAACACCTTCTAACCCGCTTTTAAAAGTAACAGATATTCGTGCTGTTTCTACA
CTTGCAAAATCTATTGGCGCTCTTACTTTTGTTGATAATACATTTTTGACACCACTATTCCAGAAACCACTTGATCTCGG
CGCAGATGTCGTTCTTCATAGCGCTACAAAGTTCATTGCTGGTCACAGTGATGTTACTGCTGGATTAGCGGTCGTAAAAG
ATGCCGAACTTGCTCAAAAACTTGGATTTTTACAAAATGCATTCGGCGCCATTTTAGGACCTCAAGATTGCTCTCTCGTA
CTTCGCGGTCTAAAAACATTACATGTACGTCTTGAGCATTCAGCTGCGAATGCCAATAAAATTGCACAGTATTTACAAGA
GCACAGTAAAATTCAAAATGTCTATTATCCTGGCTTACAAACACATCTTGGATTTGATATTCAACAATCTCAAGCAACAT
CGGCCGGAGCTGTCCTATCCTTCACTTTACAATCAGAAGATGCACTCCGCCAATTTTTATCAAAAGTAAAATTACCTGTC
TTTGCAGTTAGTTTAGGAGCTGTCGAATCGATTCTTTCCTATCCGGCTAAAATGTCACATGCAGCACTGTCACAAGAAGC
TCGTGATGAAAGAGGTATTTCCAATTCATTACTTCGTTTATCCGTCGGCCTTGAAAATGTTGATGATTTAATATCCGACT
TTGAAAATGCCCTTTCTTATGTAGAAGAACCTGTAAATGCATAG

Protein sequence :
MSYSIDTLLLHNQYKHDPQTGAVNVPIYNTSTFHQFDVDTFGKYDYSRSGNPTREALEDIIALLEGGTKGFAFASGIAAI
STAFLLLSQGDHVLISEDVYGGTYRIITEVLSRYGVSHTFVDMTNLEEIKQNIKQNTKLFYVETPSNPLLKVTDIRAVST
LAKSIGALTFVDNTFLTPLFQKPLDLGADVVLHSATKFIAGHSDVTAGLAVVKDAELAQKLGFLQNAFGAILGPQDCSLV
LRGLKTLHVRLEHSAANANKIAQYLQEHSKIQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSEDALRQFLSKVKLPV
FAVSLGAVESILSYPAKMSHAALSQEARDERGISNSLLRLSVGLENVDDLISDFENALSYVEEPVNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-88 52
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-86 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-87 47