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Name : tkt-2 (BA_3744) Accession : NP_846005.1 Strain : Bacillus anthracis Ames Genome accession: NC_003997 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 3443715 - 3445715 bp Length : 2001 bp Strand : - Note : 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exp DNA sequence : ATGTCACATTCAATCGAACAACTTTCTATCAACACGATTCGCACATTATCCATCGATGCGATTGAAAAAGCAAACTCTGG TCACCCAGGAATGCCAATGGGTGCAGCACCAATGGCTTATACATTATGGACTCAATTTATGAAACACAATCCAAATAACC CAACGTGGTTTAACCGTGATCGTTTCGTATTATCTGCAGGTCATGGTTCAATGTTATTATACAGCCTACTTCACCTATCT GGTTATGATGTAACAATGGATGACTTAAAGAACTTCCGTCAATGGGGAAGCAAAACTCCAGGGCATCCTGAGTACGGTCA TACAGCTGGTGTAGATGCAACTACTGGTCCACTTGGACAAGGTATTGCAACTGCTGTAGGTATGGCAATGGCAGAAAGAC ATTTAGCTGCTAAATATAACCGTGATGCGTATAATATAGTAGATCATTATACATACGCTATTTGTGGTGATGGAGATTTA ATGGAAGGCGTTTCTGCTGAAGCATCTTCATTAGCTGCTCATTTACAATTAGGTCGTCTTGTTGTGCTTTATGATTCAAA CGATATTTCATTAGATGGCGATTTAAATCGTTCATTCTCTGAAAGTGTAGAAGATCGTTACAAAGCATACGGATGGCAAG TAATCCGTGTTGAGGATGGAAACGATATTGAAGCTATCGCGAAAGCAATCGAAGAAGCGAAAGCTGACGAAAAACGCCCA ACGCTAATTGAAGTAAGAACGACAATTGGTTTCGGTTCTCCAAACAAATCAGGAAAATCAGCTTCACATGGTTCTCCACT TGGTGTAGAAGAAACAAAGTTAACGAAAGAAGCATACGCTTGGACTGCTGAACAAGACTTCCATGTAGCAGAAGAAGTAT ATGAAAACTTCCGTAAAACAGTACAAGATGTTGGTGAAACTGCACAAGCTGAGTGGAATACTATGCTAGGTGAATATGCA CAAGCATATCCAGAATTAGCAAACGAACTGCAAGCAGCAATGAACGGTCTTCTTCCAGAAGGTTGGGAGCAAAACTTACC AACTTATGAATTAGGATCAAAAGCAGCAACTCGTAATTCTTCAGGTGCTGTAATTAATGCAATTGCAGAGTCTGTACCAT CATTCTTCGGTGGATCTGCTGACCTTGCTGGTTCTAACAAAACATACATGAATAACGAAAAAGACTTTACAAGAGATGAT TACAGCGGTAAAAACATTTGGTACGGTGTACGTGAGTTCGCAATGGGTGCAGCAATGAACGGTATTGCACTACATGGTGG TTTAAAAACTTACGGTGGTACGTTCTTCGTATTCTCTGACTACTTACGCCCAGCAATTCGTCTTGCAGCATTAATGCAAT TGCCGGTAACGTATGTATTCACACACGACAGTATCGCTGTTGGTGAAGATGGTCCAACACATGAACCAATCGAGCAATTA GCAGCGCTACGTGCAATGCCAAATGTATCTGTTATTCGTCCAGCTGACGGTAACGAATCTGTTGCAGCTTGGAGACTAGC TCTAGAATCTACAAACAAACCAACTGCTTTAGTATTAACTCGTCAAGATCTTCCAACATTAGAAGGTGCAAAAGACGATA CGTATGAAAAAGTAGCAAAAGGTGCGTATGTAGTTTCTGCAAGCAAGAAAGAAACAGCTGATGTAATCTTACTTGCAACT GGATCTGAAGTAAGTCTAGCTGTTGAAGCTCAAAAAGCATTAGCAGTAGACGGCGTTGATGCATCTGTTGTCAGCATGCC ATCTATGGATCGCTTTGAAGCTCAAACAGCTGAGTACAAAGAATCTGTATTACCAAAAGCAGTAACAAAACGTTTCGCAA TCGAAATGGGTGCTACATTCGGATGGCACCGTTACGTAGGTCTTGAAGGAGATGTGTTAGGTATCGATACATTCGGTGCT TCTGCTCCTGGTGAGAAGATTATGGAAGAGTATGGATTTACTGTAGAGAACGTTGTTCGTAAAGTAAAAGAAATGCTTTA A Protein sequence : MSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRDRFVLSAGHGSMLLYSLLHLS GYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNIVDHYTYAICGDGDL MEGVSAEASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIAKAIEEAKADEKRP TLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYENFRKTVQDVGETAQAEWNTMLGEYA QAYPELANELQAAMNGLLPEGWEQNLPTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSNKTYMNNEKDFTRDD YSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQL AALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAKGAYVVSASKKETADVILLAT GSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLEGDVLGIDTFGA SAPGEKIMEEYGFTVENVVRKVKEML |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 1e-155 | 50 |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 2e-155 | 50 |
