Gene Information

Name : tkt-1 (BA_3432)
Accession : NP_845716.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 3154028 - 3156052 bp
Length : 2025 bp
Strand : -
Note : 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exp

DNA sequence :
ATGACACAAAACATAAATCAATTAGCAGTGAATACAATTCGTACGTTATCAATTGATGCTATTAATGCGGCAAATTCAGG
TCATCCAGGTCTTCCGATGGGAGCAGCGCCAATGGCTTATGCATTATGGGCGAATCATTTAAATCATAATCCTAATCATC
CAAAATGGTTTAACCGTGATCGCTTCGTTTTATCGGCGGGGCATGGATCTAGCTTATTATATAGCCTACTTCATTTAGCT
GGATATGACGTTTCAATTGATGACTTGAAAAACTTCAGAAAGTTAAATAGTAAAACACCAGGACATCCTGAGTTTGGTCA
TACTTCTGGAGTTGAAGCGACGACAGGCCCGTTAGGACAAGGGATTGCCAATGCTGTCGGAATGGCAATGGCAGAAGCGC
ATTTAGCAGCGAAGTTTAATAAGGATGGTCACTCTATTATAGATCACAATACGTACGCTTTAGTCGGAGACGGTGATTTA
ATGGAAGGTGTCGCTTATGAAGCGATGTCAATGGAAGGTGTCGCTTATGAAGCGATGTCAATGGCAGGACATATGAAACT
TGGCAAGTTAATTGTGCTGTATGATTCAAATGAAATTTCACTTGATGGTGAATTAAACATTGCTTTCTCTGAAGATATGC
AGAAAAGGGTAGAATCTGCACATTGGCAATATGTAAGAGTTGAAGATGGAAACGATGTTGATGCGATTACAAAAGCGATT
CAATTAGCGAAAGATAATACGGACCAACCTACTCTTATAGAGATTAGAACCGTTATAGGTTACGGAAGTCCAAAAGTTGC
TGGAACGAACAAAGCACATGGTAACCCGCTTGGATTAGAAGAAGCGACAGCGACAAAACAAGTGTATGGTTGGCATTATG
AAGAAGACTTCTTTGTACCTGAAGAAGTAACAGCTCATTTTAATGAACTGAAACAAAAAGGTATTGAAAAAGAACGTGGC
TGGAATGAGCAGTTCAACTTATACAGAGAGTCAAATCCTGCACTAGCAGATGAATTAGAAAAAGCAATTATAGGTGAAGT
TTTAATCGAAGCGAAAGACATTCTATCCTTTGATAGTGAAAAAACGATTTCAACTCGTGTTGCAAGTGGGGAAGCTATTA
ATCATTATGTGAAATCGATTCCTTCTATTTTCGGTGGAAGTGCGGATCTTTCTCATTCTACGATGACAGATATAAAAGGG
GAAGCAGTGTATGCGGTAGAATCGTATGCTGGCCGAAATATATACTTTGGTGTACGTGAACATGCAATGGGCGCAGCAGC
GAATGGACTGGCTCTTCATGGAGGAGTAAAACCGTTCGTGAGTACATTCTTTGTATTTAATGACTATCTTCGTCCATCTA
TTCGACTGGCTGCATTGCAAAAGTTACCTGTTACGTACGTATTTACACATGATTCAATTGCTGTAGGAGAAGATGGTCCA
ACGCATGAACCTATTGAACATTTAGCAGCTCTTCGGGCAATCCCTGGTTTAACAGTTATCCGTCCGTCAGATGCAAATGA
AACAGCAAGTGCGTGGGCGTATGCTTTACAGCAAACGGAAGGTCCAGTCGTTTTAGTACTGAGCCGTCAAAATTTACCGG
TGTTTCATGAAACGAAAGCAAACATAGAGAATCTTTCTAAAGGGGCTTACGTATTAACACAAACGAATGAAAATCCGGAT
GTAATTTTAATTGCGACAGGTTCTGAAGTATCCTTAGCTGCTAGTGCGAAAGCGAAACTAGAAGAAGACAATGTCTCTGT
TCGCATCGTTGCAATGCCAAGCTGGGAGTTATTCGATCGCCAATCGAAAGAATATAAAGAATCCGTTCTTCCGTCTTCTG
TAACGAAACGAGTATCTCTTGAGATGGGTGTATCTCTCGGCTGGGAGCGTTATGTAGGACAAGAAGGAAACATATTATCG
ATTGAAACATTTGGAGCTTCAGGAACTGGGGCTGAAGTCATGAATCTATTTGGATTTACGACAGAAAATGTTGTTCAAAT
TACAAAAAATGTATTAAATTCTTAA

Protein sequence :
MTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLA
GYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDL
MEGVAYEAMSMEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAI
QLAKDNTDQPTLIEIRTVIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKERG
WNEQFNLYRESNPALADELEKAIIGEVLIEAKDILSFDSEKTISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKG
EAVYAVESYAGRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGP
THEPIEHLAALRAIPGLTVIRPSDANETASAWAYALQQTEGPVVLVLSRQNLPVFHETKANIENLSKGAYVLTQTNENPD
VILIATGSEVSLAASAKAKLEEDNVSVRIVAMPSWELFDRQSKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILS
IETFGASGTGAEVMNLFGFTTENVVQITKNVLNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-131 48
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-125 44