Gene Information

Name : BA_3355 (BA_3355)
Accession : NP_845641.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Virulence
Product : thiol-activated cytolysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3086298 - 3087836 bp
Length : 1539 bp
Strand : -
Note : 'similar to SP:Q45105, GB:D13292, GB:X67016, SP:P31431, PID:1944492, PID:286021, and PID:28680; identified by sequence similarity'

DNA sequence :
GTGATTTTTCTGAATATTAAGAAAAACACTAAAAGAAGAAAGTTCCTTGCATGTTTATTAGTTAGTCTATGTACCATTCA
TTATTCGTCTATTTCTTTTGCAGAAACACAAGCCGGTAATGCAACTGGTGCAATAAAAAATGCTAGTGATATTAATACTG
GTATAGCAAATCTAAAGTATGATAGTAGAGATATTTTAGCAGTAAATGGTGATAAAGTAGAGAGTTTTATTCCGAAAGAG
AGTATCAATTCAAACGGTAAATTTGTAGTAGTGGAACGCGAGAAAAAATCACTTACAACGTCACCAGTCGATATTTTGAT
TATTGATTCTGTAGTGAATCGTACGTATCCAGGAGCTGTACAACTTGCCAATAAAGCATTTGCAGACAATCAACCGAGTT
TATTAGTAGCTAAGAGAAAGCCTTTGAATATTAGTATAGACTTACCTGGCATGAGAAAAGAAAATACAATCACTGTCCAA
AATCCGACATATGGTAATGTGGCTGGAGCAGTAGATGATTTAGTATCTACTTGGAATGAAAAGTATTCCACAACACATAC
GTTACCTGCAAGAATGCAGTATACAGAATCTATGGTTTATAGTAAATCACAAATCGCAAGTGCTCTTAATGTTAATGCTA
AATATCTTGATAACAGTCTAAATATTGACTTTAATGCAGTTGCAAATGGAGAAAAGAAAGTGATGGTGGCGGCATATAAA
CAAATATTTTATACTGTAAGTGCTGAACTACCTAATAATCCATCTGATCTCTTTGATAATAGTGTTACTTTTGATGAGTT
AACTCGTAAAGGAGTAAGTAATTCGGCTCCACCTGTTATGGTTTCAAATGTAGCTTATGGTAGAACGGTTTATGTAAAAT
TAGAAACAACATCTAAGAGTAAAGATGTACAAGCTGCATTTAAAGCTCTACTTAAGAATAACAGCGTCGAAACGAGTGGA
CAGTACAAAGATATTTTTGAAGAAAGTACCTTTACTGCTGTAGTATTAGGCGGAGATGCGAAAGAGCATAACAAGGTTGT
TACAAAAGATTTCAATGAAATCCGAAATATTATTAAAGATAATGCTGAATTAAGCTTTAAAAATCCAGCATACCCAATTT
CATATACAAGCACGTTCTTAAAAGATAATGCAACTGCTGCTGTTCATAACAATACAGATTATATCGAGACGACAACTACA
GAATATTCAAGTGCTAAAATGACACTCGATCATTACGGTGCTTACGTTGCTCAATTTGATGTATCTTGGGATGAATTTAC
ATTTGATCAAAATGGGAAAGAAGTACTAACACATAAAACATGGGAAGGTAGTGGCAAAGACAAAACAGCCCATTACTCTA
CAGTTATCCCTCTTCCACCAAATTCAAAAAATATAAAAATCGTTGCAAGAGAATGTACAGGTCTTGCATGGGAATGGTGG
AGAACTATCATTAATGAACAAAATGTTCCATTAACAAATGAAATAAAGGTTTCAATTGGAGGAACAACATTATATCCAAC
TGCTACTATTAGTCATTAG

Protein sequence :
MIFLNIKKNTKRRKFLACLLVSLCTIHYSSISFAETQAGNATGAIKNASDINTGIANLKYDSRDILAVNGDKVESFIPKE
SINSNGKFVVVEREKKSLTTSPVDILIIDSVVNRTYPGAVQLANKAFADNQPSLLVAKRKPLNISIDLPGMRKENTITVQ
NPTYGNVAGAVDDLVSTWNEKYSTTHTLPARMQYTESMVYSKSQIASALNVNAKYLDNSLNIDFNAVANGEKKVMVAAYK
QIFYTVSAELPNNPSDLFDNSVTFDELTRKGVSNSAPPVMVSNVAYGRTVYVKLETTSKSKDVQAAFKALLKNNSVETSG
QYKDIFEESTFTAVVLGGDAKEHNKVVTKDFNEIRNIIKDNAELSFKNPAYPISYTSTFLKDNATAAVHNNTDYIETTTT
EYSSAKMTLDHYGAYVAQFDVSWDEFTFDQNGKEVLTHKTWEGSGKDKTAHYSTVIPLPPNSKNIKIVARECTGLAWEWW
RTIINEQNVPLTNEIKVSIGGTTLYPTATISH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 8e-150 62
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 2e-100 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BA_3355 NP_845641.1 thiol-activated cytolysin VFG2275 Protein 5e-172 69
BA_3355 NP_845641.1 thiol-activated cytolysin VFG0976 Protein 3e-150 62
BA_3355 NP_845641.1 thiol-activated cytolysin VFG1363 Protein 6e-102 43
BA_3355 NP_845641.1 thiol-activated cytolysin VFG0074 Protein 1e-100 42