Gene Information

Name : serS (BA_0012)
Accession : NP_842583.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 20338 - 21612 bp
Length : 1275 bp
Strand : +
Note : 'catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA'

DNA sequence :
ATGCTTGATATTAAATTTTTACGTACAAATTTTGAAGAAGTAAAAGCAAAGTTACAGCATAGAGGCGAAGATTTAACTGA
TTTTGGTCGCTTTGAAGAATTGGATACGAGAAGAAGAGAACTACTTGTTCAAACAGAGGAACTAAAAAGTAAACGTAACG
AAGTATCTCAACAAATCTCTGTATTGAAGCGCGAAAAGAAAGATGCAGAAGCTCTAATTCTAGAAATGCGTGAAGTTGGA
GAAAAAGTAAAAGATCTTGATAATGAACTTCGTACAGTTGAAGAAGATTTAGAAAGATTGATGTTATCTATTCCAAATAT
CCCTCACGAATCTGCTCCAGTTGGTGAAACAGAGGATGATAATGTAGTAGCTCGTACTTGGGGAGAAGTGAAAGAATTTG
CTTTTGAACCAAAACCACATTGGGATCTTGCTACAGATTTAGGAATCTTAGATTTTGAGCGTGCTGGAAAAGTAACAGGA
AGCCGCTTCGTATTCTACAAAGGTGCTGGCGCAAGATTAGAGCGTGCTTTAATTAGCTTTATGCTTGATCTTCATACTGA
TGAGCATGGATATGAAGAAGTATTACCTCCGTACATGGTAAACCGTGCAAGCATGACAGGGACAGGACAACTTCCGAAGT
TTGAAGAAGATGCATTCCGTATTGAAAGTGAAGACTACTTCTTAATTCCAACAGCTGAAGTACCTGTAACAAATATGCAC
CGTGATGAAATCTTAAATAAAGAGCAATTACCTATAAGATATGCTGCATTTAGCTCTTGTTTCCGTTCTGAAGCAGGTTC
AGCTGGCCGTGATACACGTGGTTTAATTCGTCAGCATCAGTTCAATAAAGTAGAGCTTGTAAAGTTCGTAAAACCAGAAG
ATTCTTACGAAGAGTTAGAAAAACTAACAAATGATGCAGAACGCGTGTTACAATTATTAGAGTTGCCATATCGCGTTATG
AGCATGTGCACAGGCGATTTAGGATTTACAGCAGCGAAGAAATACGATATCGAAGTATGGATTCCAAGCTATGGCACATA
TCGTGAAATCTCTTCTTGTAGTAATTTCGAGGCTTTCCAAGCGAGACGTGCAAATATCCGTTTCCGTCGTGAGCCAAACG
GCAAACCAGAACATGTTCATACATTAAATGGATCTGGTCTTGCAATTGGACGTACGGTAGCAGCTATTTTAGAGAACTAC
CAACAAGAAGATGGTACAATTATAATTCCAGAAGTTCTTCGCCCTTATATGGGAGGAAAAACAGTTATTAAGTAA

Protein sequence :
MLDIKFLRTNFEEVKAKLQHRGEDLTDFGRFEELDTRRRELLVQTEELKSKRNEVSQQISVLKREKKDAEALILEMREVG
EKVKDLDNELRTVEEDLERLMLSIPNIPHESAPVGETEDDNVVARTWGEVKEFAFEPKPHWDLATDLGILDFERAGKVTG
SRFVFYKGAGARLERALISFMLDLHTDEHGYEEVLPPYMVNRASMTGTGQLPKFEEDAFRIESEDYFLIPTAEVPVTNMH
RDEILNKEQLPIRYAAFSSCFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYEELEKLTNDAERVLQLLELPYRVM
SMCTGDLGFTAAKKYDIEVWIPSYGTYREISSCSNFEAFQARRANIRFRREPNGKPEHVHTLNGSGLAIGRTVAAILENY
QQEDGTIIIPEVLRPYMGGKTVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-130 62