Gene Information

Name : nrdF (BA_1372)
Accession : NP_843830.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1308135 - 1309103 bp
Length : 969 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGCGTGCGGTAAACTGGAACAAAAAAGAAGATGATTTTAGTTTAATGTTTTGGAAGCAAAACATCGCTCAGTTTTGGAC
AGAAGAAGAAATCGCGGTGTCTTCTGACAAAAATACTTGGGTGCAATTATCAAAAGAAGAGCAAATTGCTTATAAGCGTG
TATTAGGTGGTTTAACACTTTTAGATACGAAACAAGGCGGCGAAGGGATGCCACTTGTACTTGTTCATCTTGAAAATTTA
CAAGCAAAAAGCGTATTAGCTTTCATGGGTGCTATGGAAGAAGTACATGCGAAGAGTTATAGTCATATTTTCACAACGTT
AGCTACTGAAGAAGAAATCGATGAGATTTTTGACTGGGTAGATACTCATCCGTTACTTGAGAAAAAGGCTGGTATTATTA
CAAGTTACTATCGTCGTTTATTAAAACCTGAAGTGACGAAAAAAGAGTTATACATGGCAATGGTAGCAAGTGTGTTCTTA
GAAAGTTACTTATTCTATAGTGGATTCTTCTATCCACTTTACTTAGCTGGTCAAGGAAAACTTACGGCGAGTGGTGAGAT
TATTAACTTAATAATTCGTGATGAGTCAATTCACGGCGTATTCGTCGGTATTTTAGCACAACAAATCTTCGCAGAACTTT
CTGCAGAAGATCAACAAGAAGTGCAAAAAGAAACGCAAGAGTTATTAATGGAACTATATGAAATCGAAATGGCATACACA
GAAGAAATTTACACTTCTATCGGTCTTGTAGAAGATGTAAATCGCTTCGTTCGTTACAATGCGAATAAAGGACTTATGAA
CTTAGGACTTGAGCCGAAGTTTGAAGAAGAAGAAATTAACCCAATCGTTTTAAATGGTTTACGTACAGATACGAAAAACC
ATGATTTCTTCTCTGTAAAAGGAAATGGTTACGTAAAAGCAACGAACGTTGAAAAGTTATCTGATGATGACTTCGTGTTT
AATTTTTAA

Protein sequence :
MRAVNWNKKEDDFSLMFWKQNIAQFWTEEEIAVSSDKNTWVQLSKEEQIAYKRVLGGLTLLDTKQGGEGMPLVLVHLENL
QAKSVLAFMGAMEEVHAKSYSHIFTTLATEEEIDEIFDWVDTHPLLEKKAGIITSYYRRLLKPEVTKKELYMAMVASVFL
ESYLFYSGFFYPLYLAGQGKLTASGEIINLIIRDESIHGVFVGILAQQIFAELSAEDQQEVQKETQELLMELYEIEMAYT
EEIYTSIGLVEDVNRFVRYNANKGLMNLGLEPKFEEEEINPIVLNGLRTDTKNHDFFSVKGNGYVKATNVEKLSDDDFVF
NF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nrdF YP_189075.1 ribonucleotide-diphosphate reductase subunit beta Not tested ¥ÕSP¥â Protein 7e-76 53
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 5e-56 43