Gene Information

Name : nrdE (BA_1371)
Accession : NP_843828.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1304855 - 1308041 bp
Length : 3187 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGCGACACATTGAACTGAATAATGAAATCACGCAAATGCAGGACGGTTTTTATCAGCTTCATAAAGATAAAGAGGCATT
AGAAGTCTTTATGGAAGAAGCTAGAGAGAATACCGTTCATTTTAATAGCGTGGCAGAGCGAATGGAGTATATGAAAGAAC
ATGATTACTATTACAACGTTCTGGACGAGTATAACTTGGAGGAAGTAGAAGAGGTATATAACATCGCTTATGGTGAAAAC
TTCGAGTTCCAATCTTATATGGCAGCATCTAAGTTTTACAAAGATTATGCGTTAAAAACAAATGATCAAAAACAATACTT
AGAAAGCTATGAAGATCGTGTAGCAATTGTGTCATTATACTTAGGACGCGGTGATGTTGCCAAGGCAAAACAATTCGCAA
GCATGATTGTCAAACAAAACTACCAACCAGCAACACCAACCTTTTTAAATGCGGGAAGAAGCAGAAGAGGAGAAATGGTG
TCTTGTTTCTTGTTAGAGATGGATGATAGCTTAAATTCAATCGGCTTTAACATTAATACTGCAATGCAATTATCAAAAAT
CGGCGGAGGAGTAGCTTTAAACTTATCTAAGCTACGCGCACGTGGTGAGCAAATTAAAGGTATCGACAACGCTGCAAGTG
GTGTAGTACCTGTTATGAAGTTACTTGAAGATTCGTTTTCATATGCGAATCAGCTTGGCCAACGAAAAGGTGCTGGCGCA
GTATACTTGAACATTTTCCATTGGGATATTATTGAATTCCTGGATTAATTGGTAGTCCCTCTACACAGTAATGTGTATGA
GAAAACCTTGTGAACCTAACCAATAGGGTGTCGCATTAGCGGCTAACGGTATCAGTTGAATAAGGGGTAAAAGAAAAAGA
ACCCGCGAAGAAGCTGACTAAGAGAGCCTACGGTCCATGCAAGTGGATAGCAGGTAATACCGTGCCAAGCTTGAAAGAAA
TATTACTTGGGTGAAGTGGAATCTTATATTCACCGGAGGCGAGATTCCATGAACTGTGGAATTTATTTGATAATTAATAA
GGAAAACAGGAAGTTTTATATTGGTAGTTCTAATAATTTTAAAGTGCGATTTAAAACTCATAGAAATCAATTGAATGCTA
ATCAGCATCATAGTAAACATTTACAAGCAGCCTGGAATTTATATGGTGAGAATAAATTTGAGTTTAAAGGGATAATTGAA
TTACCAAATGATAAGGACATTCTTCATAAGATAGAGCAAAGTTTATTAAGTCAATATTATGGGAAACAGTATTGCTACAA
TGGACATCCTATCGCTAGAGGTGGGGCGCTGAGTGGGGAAAAGAACCATATGTATGGGAAAACCCACTCAAAGGAAGTAA
AAAAATTTCTTTCTGAAATTAATACTGGGCCTAATAATTATTGGTATGATAAACCTCAACATCTGGAGAATATGAGATCT
AAGATTACTAAACGATTTCATGGTAGAAAACATACTGATGAAACAAAAGAAAAAATGTCTAGATCTCGTAAAGGTAAAAA
GCATACAAAAGAAACATGTATGAAGATAAGTAAAGCTCAAAAAAATCAATATAATTCAGGTAGAGAAAAACAAAAAAAGC
CAATTGTTATAAATGACATTTACTATGAGTCTTTAGCAGAAGCCGGACGAGCGTTTAATGTACCTGCTAATACGATAAAA
TATAGAGTACTATCCAATAACTTTCCTAATTATCAATACTTTCAAGAAGGTGTAGAGACTATCGAACGCGCGTCATTAGA
CGAAAGCTAGTAGAGTAGGCTGGAAATAGGTACCAGTCGAAGTGCAAGGCAACCAGTTACAGGTTGATGATATAGTCCAA
CCTTCATAGAAATATGAAGACGAGTTGACCAAAAAAATAAATGCCGATGAGAAGAGCCGTATTCAGTCTCTATCAATCGG
AATTATCGTTCCAAGTAAGTTCTTTGAGCTTGCTGAGAAAAACGAACCTTTCCATGTTTTCGCGCCTTATACTGTATATA
AAGAATACGGAAAGCATTTAGATGACATTGATATCGATGAAATGTACGATGAATTAATGAGCAATCCAAAAGTGAAGAAG
AAGCCGCTAGATATTAGTGCGCGTGATATGCTTATTAAAATTGCTATGATTCAGCTTGAGTCTGGTTATCCGTACTTAAT
GTTTAAATCAAATGCAAATAACCAACATCCATTGAAGGACATTGGAACTGTGAAGATGTCCAACTTGTGTACAGAAATCT
TCCAGCTACAAGAAACTTCTGAAATTAACGATTACGGTACAGATGACATTATTCGTCGTGATATTAACTGTAACTTAGGA
TCGTTAAATATCGTAAATGTAATGGAAAATAAAGAAATTCGTGAAGCAGTTCATGCGGGAATGGAAGCTTTAACAGCTGT
TTCTGATATGACGATCATTCCGAATGCACCAACTGTGAAAAAAGCAAATGATGAGCTTCATTCAGTTGGGCTTGGCGCAA
TGAACTTACACGGATATTTAGCAAAAAATAAAATCGCTTATGAAAGTGAAGAAGCGAAAGAGTTCGCTCGTACATTCTTT
ATGATGTTAAATTACTACTCTATTGAGAAAAGTATGGAAATCGCTAAAGAAAAAGGCGAAACATTTAAAGACTTCGATAA
ATCTGATTATGCGAATGGGACATACTTTGAAAAGTATGAAACGACAGATTACAGCCCAGTAACTGAAAAAGTTCAGCAAT
TATTTGAAGGAATTCATATTCCAACAAAAGAAGATTGGACAAGTTTAAAAGAGCAAGTGCAGAAGAATGGTTTATACAAC
TCATATCGTCTTGCTATCGCTCCGACACAATCAATCAGTTACGTTCAAAATGCAACTTCAAGCGTAATGCCTATCGTAAG
TCAAATCGAATCAAGAACGTATGCGAATGCGACAACATATTATCCAATGCCGTATTTATCAAAAGATACGTTCTGGTACT
ATAAATCTTCTTACGATATGAATCAGTTTAAATTAATTGATTTAATCGCAGAAATTCAAGAACATATTGACCAAGGAATT
AGTACAATTCTTTACGTTAATAGTGATATTTCAACACGTGAATTAGCACGTTACTACATCTATGCACATAAAAAAGGCTT
AAAGAGTCTGTATTATACGAGAACACGTAAATTAAGCGTGGAAGAGTGTGTGGCTTGTACTGTTTAA

Protein sequence :
MRHIELNNEITQMQDGFYQLHKDKEALEVFMEEARENTVHFNSVAERMEYMKEHDYYYNVLDEYNLEEVEEVYNIAYGEN
FEFQSYMAASKFYKDYALKTNDQKQYLESYEDRVAIVSLYLGRGDVAKAKQFASMIVKQNYQPATPTFLNAGRSRRGEMV
SCFLLEMDDSLNSIGFNINTAMQLSKIGGGVALNLSKLRARGEQIKGIDNAASGVVPVMKLLEDSFSYANQLGQRKGAGA
VYLNIFHWDIIEFLDTKKINADEKSRIQSLSIGIIVPSKFFELAEKNEPFHVFAPYTVYKEYGKHLDDIDIDEMYDELMS
NPKVKKKPLDISARDMLIKIAMIQLESGYPYLMFKSNANNQHPLKDIGTVKMSNLCTEIFQLQETSEINDYGTDDIIRRD
INCNLGSLNIVNVMENKEIREAVHAGMEALTAVSDMTIIPNAPTVKKANDELHSVGLGAMNLHGYLAKNKIAYESEEAKE
FARTFFMMLNYYSIEKSMEIAKEKGETFKDFDKSDYANGTYFEKYETTDYSPVTEKVQQLFEGIHIPTKEDWTSLKEQVQ
KNGLYNSYRLAIAPTQSISYVQNATSSVMPIVSQIESRTYANATTYYPMPYLSKDTFWYYKSSYDMNQFKLIDLIAEIQE
HIDQGISTILYVNSDISTRELARYYIYAHKKGLKSLYYTRTRKLSVEECVACTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 2e-146 46