Gene Information

Name : clpB (BA_1177)
Accession : NP_843655.1
Strain : Bacillus anthracis Ames
Genome accession: NC_003997
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1141925 - 1144525 bp
Length : 2601 bp
Strand : +
Note : 'similar to GP:16411676, and SP:Q9RA63; identified by sequence similarity'

DNA sequence :
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCACCATCA
AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAGGATGGGCTAGCAGTACGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCATTAAAACAAGGCGTAGAAAATTTAATTAAGAAAAAGCCTTCCGTAACGGGAAGCGGTGCAGAA
GCAGGTAAATTATATATAACAGGTGCCCTGCAACAACTGCTTGTAAGAGCAGGAAAAGAAGCAGAGAAATTGCAAGATGA
TTACATTTCAGTGGAACATGTATTACTTGCTTTTACTGAAGAAAAAGGCGATATAAGCCAATTGTTTACAAGATTTCATA
TTACGAAAGACAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGCCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTGAAAGCAGGGAAAATTGACCCTGTTATCGGCCGCGA
TAGTGAAATTCGCCGCGTAATCCGCATTCTTTCACGTAAAACGAAAAATAACCCTGTTTTAATTGGTGAGCCAGGTGTTG
GTAAAACAGCAATCGTTGAAGGGTTAGCACAGCGTATTGTGAAGAAGGATGTACCTGAAGGATTAAAAGATAGAACAATC
TTTGCGTTAGATATGAGTGCGCTTGTAGCTGGTGCGAAATTCCGTGGTGAGTTCGAAGAGCGTTTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGTCGCATTTTACTATTCATTGATGAACTTCACACAATCGTCGGCGCTGGAAAAACAGAAG
GTGCGATGGATGCAGGGAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATTGGGGCGACAACCCTAGAT
GAATATCGTAAATATATTGAGAAAGATCCAGCACTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCTATTTTACGTGGTTTAAAAGAGCGTTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCAATTG
TAGCAGCATCAGTTTTATCAGATCGATATATTTCAGATCGTTTCTTACCGGATAAAGCAATTGATCTTGTTGACGAAGCG
TGCGCAACAATTCGTACAGAAATTGATTCTATGCCGACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTAGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGCCTCAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTGGCAAGTAGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAGAGCAGCGGAACTTCGCCACGG
AAAAATTCCTGCAATTGAAAAAGAGTTAAAAGAAGCAGAAGAAATGGGCGCAAATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAGATTGCTGATATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT
GAACGTGAGAAATTATTACGCTTAGAGCAAATTTTATCAGAACGTGTTATCGGACAAGAGGAAGCGGTAAGCTTAGTATC
AGATGCAGTTCTTCGTGCGCGCGCTGGTATTAAAGACCCGAACCGTCCAATTGGTTCCTTCATCTTCTTAGGACCGACTG
GTGTTGGTAAAACAGAGCTTGCCAAAACGTTAGCACAGTCTTTATTTGATAGTGAAGAGCAAATGATTCGTATCGATATG
TCTGAGTATATGGAGAAACACGCTGTGTCACGCTTAATTGGTGCCCCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACAGAAGCAGTAAGACGTAAACCGTATTCCGTTATTTTATTAGACGAAATCGAAAAAGCGCATCCAGAAGTATTCA
ATATTTTATTACAAATGTTAGATGACGGACGCATTACAGATTCGCAAGGTCGTACAGTGGACTTTAAAAATACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGAAGATGGCTCCATTAAAGAAGAATCAAGAGA
ACTTGTAATGGGACAATTGAGAGGACATTTCCGACCAGAGTTCTTAAACCGCGTCGACGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCATATTACG
GTAAAATTAACAGAAGCAGCGAAAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTACGGAGCTCGTCCATTAAAACG
ATATGTACAGCGTCAAGTTGAAACGAAATTAGCGAGAGAATTAATTGCAGGTACGATTACTGACAATAGTCATGTAGTGG
TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAAATAA

Protein sequence :
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVENLIKKKPSVTGSGAE
AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDISQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVKAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGANNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEEDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VKLTEAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-107 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_843655.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG0079 Protein 0.0 49
clpB NP_843655.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2084 Protein 4e-110 42