Gene Information

Name : set21 (MW0387)
Accession : NP_645204.1
Strain : Staphylococcus aureus MW2
Genome accession: NC_003923
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 435077 - 435775 bp
Length : 699 bp
Strand : +
Note : exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence :

ATGAAATTAAAAGCGTTAGCTAAAGCAACATTAGTATTGGGATTGTTAGCTACTGGTGTAATAACAACAGAAAGTCAAAC
AGTAAAAGCGGCAGAATCAACTCAAGGTCAACACAATTATAAATCATTAAAATACTACTATAGCAAGCCAAGTATAGAGT
TAATAAATGTAGATGGTCTGTATAGACAACATTTAACTGATAAAGGTGCATATGTATGGAAAAATCTTAAAGATTATTAT
ATTGGGCTACTAGGTGAAGATAGTAAGAAATTCAAATCAGATGTATACGGGGACCTAGATGCATTTTTAGTCATAGAAGA
AGAACCTGTTAAAGGAAGACAATATTCAATTGGCGGTATAAGTAAGACAAATAGTAAAGAATTTAAAGAAAGAGAAGTCG
ATGTTAAAGTAACAAGAAAAGCAGACAGAGATACTACATCAACTAAAGATAGTAAATTTAAAATTACAAAAGAAGAAATC
TCGTTAAAAGAGTTAGATTTTAAATTAAGACAAAAATTGATGAAAGAAGAGAATTTATACGATGCAATTAACCATAGAAA
AGGTAAAATTGTAGTTAAAATGGAAGATGATAAGTTTTATACTTTCGAACTTACAAAAAAATTACAACCGCATCGCATGG
GTGACACGATAGATGGTACCAAAATCAAAGAAATTAATGTTGAGCTAGAATATAAATAA

Protein sequence :

MKLKALAKATLVLGLLATGVITTESQTVKAAESTQGQHNYKSLKYYYSKPSIELINVDGLYRQHLTDKGAYVWKNLKDYY
IGLLGEDSKKFKSDVYGDLDAFLVIEEEPVKGRQYSIGGISKTNSKEFKEREVDVKVTRKADRDTTSTKDSKFKITKEEI
SLKELDFKLRQKLMKEENLYDAINHRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELEYK

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
SAS0389	YP_042514.1	superantigen-like protein	Virulence	vSa¥á	Protein	5e-86	100
set21	NP_645204.1	superantigen-like protein	Virulence	vSa¥á	Protein	5e-86	100
set6nm	YP_001331427.1	superantigen-like protein	Virulence	vSa¥á	Protein	5e-67	82
SAUSA300_0400	YP_493114.1	superantigen-like protein	Virulence	vSa¥á	Protein	5e-67	82