Gene Information

Name : set19 (MW0385)
Accession : NP_645202.1
Strain : Staphylococcus aureus MW2
Genome accession: NC_003923
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 432616 - 433563 bp
Length : 948 bp
Strand : +
Note : exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence :
ATGAAAATAACAACAATTGCTAAAACAAGTTTAGCACTAGGCCTTTTAACAACAGGTGTAATCACAACGACAACGCAAGC
AGCAAATGCGACAACACCGCCTTCAACTAAAGTGGAAACACCGCAACAAGTAGCAAATGCAACAACACCATCTTCAACTA
AAGTGGAAGCACCGCAACAAGCAGCAAACGCGACAACACCATCTTCAACTAAAGTAGAAGCACCGCAATCAAAACCAAAC
GCGACAACACCATCTTCAACTAAAGTGGAAGCACCGCAACAAGCAGCAAACGCGACAACACCACCTTCGTCTAATGTAGA
CACATCACCACCACAATCGCCAACCACAAAACAAGTACCAACAGAAATAAATCCTAAATTTAAAGATTTAAGAGCGTATT
ATACGAAACCAAGTTTAGAATTTAAAAATGAGATTGGTATTATTTTAAAAAAATGGACGACAATAAGATTTATGAATGTT
GTCCCAGATTATTTCATATATAAAATTGCTTTAGTTGGTAAAGATGATAAAAAATATGGTGAAGGAGTACATAGGAATGT
CGATGTATTTGTCGTTTTAGAAGAAAATAATTACAATCTCGAAAAATATTCTGTCGGTGGTATCACAAAGAGTAATAGTA
AAAAAGTTGATCACAAAGCAGGAGTAAGAATTACTAAGGAAGATAATAAAGGTACAATCTCTCATGATGTTTCAGAATTC
AAGATTACTAAAGAACAGATTTCCTTGAAAGAACTTGATTTTAAATTGAGAAAACAACTTATTGAAAAAAATAATCTGTA
CGGTAACGTTGGTTCAGGTAAAATTGTTATTAAAATGAAAAACGGTGGAAAGTACACGTTTGAATTGCACAAAAAATTAC
AAGAAAATCGCATGGCAGATGTCATAGATGGCACTAATATTGATAACATTGAAGTGAATATAAAATAA

Protein sequence :
MKITTIAKTSLALGLLTTGVITTTTQAANATTPPSTKVETPQQVANATTPSSTKVEAPQQAANATTPSSTKVEAPQSKPN
ATTPSSTKVEAPQQAANATTPPSSNVDTSPPQSPTTKQVPTEINPKFKDLRAYYTKPSLEFKNEIGIILKKWTTIRFMNV
VPDYFIYKIALVGKDDKKYGEGVHRNVDVFVVLEENNYNLEKYSVGGITKSNSKKVDHKAGVRITKEDNKGTISHDVSEF
KITKEQISLKELDFKLRKQLIEKNNLYGNVGSGKIVIKMKNGGKYTFELHKKLQENRMADVIDGTNIDNIEVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
set19 NP_645202.1 superantigen-like protein Virulence vSa¥á Protein 3e-124 100
SAS0387 YP_042512.1 superantigen-like protein Virulence vSa¥á Protein 3e-124 100
set4nm YP_001331425.1 superantigen-like protein Virulence vSa¥á Protein 2e-112 89
SAUSA300_0398 YP_493112.1 superantigen-like protein Virulence vSa¥á Protein 2e-112 89
SAKOR_00408 YP_008490592.1 Exotoxin Virulence vSa¥á Protein 8e-113 88
SACOL0472 YP_185362.1 superantigen-like protein Virulence vSa¥á Protein 2e-110 87
set9 NP_373635.1 superantigen-like protein Virulence vSa¥á Protein 2e-107 86
SAR0424 YP_039876.1 superantigen-like protein Virulence vSa¥á Protein 2e-93 71
SAR0425 YP_039877.1 superantigen-like protein Not tested vSa¥á Protein 7e-85 68
SAMSHR1132_03740 YP_005324896.1 exotoxin Virulence vSa¥á Protein 4e-78 63
set6nm YP_001331427.1 superantigen-like protein Virulence vSa¥á Protein 6e-35 43
SAUSA300_0400 YP_493114.1 superantigen-like protein Virulence vSa¥á Protein 6e-35 43