Gene Information

Name : set18 (MW0384)
Accession : NP_645201.1
Strain : Staphylococcus aureus MW2
Genome accession: NC_003923
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 431181 - 432251 bp
Length : 1071 bp
Strand : +
Note : exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence :
ATGAAAATGAGAACAATTGCTAAAACCAGTTTAGCACTAGGGCTTTTAACAACAGGCGCAATTACAGTAACGACGCAATC
GGTCAAAGCAGAAAAAATACAATCAACTAAAGTTGACAAAGTACCAACGCTTAAAGCAGAGCGATTAGCAATGATAAACA
TAACAGCAGGTGCAAATTCAGCGACAACACAAGCAGCTAACACAAGACAAGAACGCACGCCTAAACTCGAAAAGGCACCA
AATACTAATGAGGAAAAAACCTCAGCTTCCAAAATAGAAAAAATATCACAACCTAAACAAGAAGAGCAGAAAACGCTTAA
TATATCAGCAACGCCAGCGCCTAAACAAGAACAATCACAAACGACAACCGAATCTACAACGCAGCAAACTAAAATGACAA
CACCTCCATCAACAAACACGCCACAACCAATGCAATCTACTAAATCAGACACACCACAATCTCCAACCATAAAACAAGCA
CAAACAGATATGACTCCTAAATATGAAGATTTAAGAGCGTATTACACGAAACCGAGTTTTGAATTTGAAAAGCAGTTTGG
ATTTTTGCTCAAACCATGGACGACGGTTAGGTTTATGAATGTTATTCCAAATAGGTTCATCTATAAAATAGCTTTAGTTG
GAAAAGATGAGAAAAAATATAAAGATGGACCTTACGATAATATCGATGTATTTATCGTTTTAGAAGACAATAAATATCAA
TTGAAAAAATATTCTGTCGGTGGCATCACGAAGACTAATAGTAAAAAAGTTAATCACAAAGTAGAATTAAGCATTACTAA
AAAAGATAATCAAGGTATGATTTCACGCGATGTTTCAGAATACATGATTACTAAGGAAGAGATTTCCTTGAAAGAGCTTG
ATTTTAAATTGAGAAAACAACTTATTGAAAAACATAATCTTTACGGTAACATGGGTTCAGGAACAATCGTTATTAAAATG
AAAAACGGTGGGAAATATACGTTTGAATTACACAAAAAACTGCAAGAGCATCGTATGGCAGACGTCATAGATGGCACTAA
TATTGATAACATTGAAGTGAATATAAAATAA

Protein sequence :
MKMRTIAKTSLALGLLTTGAITVTTQSVKAEKIQSTKVDKVPTLKAERLAMINITAGANSATTQAANTRQERTPKLEKAP
NTNEEKTSASKIEKISQPKQEEQKTLNISATPAPKQEQSQTTTESTTQQTKMTTPPSTNTPQPMQSTKSDTPQSPTIKQA
QTDMTPKYEDLRAYYTKPSFEFEKQFGFLLKPWTTVRFMNVIPNRFIYKIALVGKDEKKYKDGPYDNIDVFIVLEDNKYQ
LKKYSVGGITKTNSKKVNHKVELSITKKDNQGMISRDVSEYMITKEEISLKELDFKLRKQLIEKHNLYGNMGSGTIVIKM
KNGGKYTFELHKKLQEHRMADVIDGTNIDNIEVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
set18 NP_645201.1 superantigen-like protein Virulence vSa¥á Protein 8e-142 100
SAS0386 YP_042511.1 superantigen-like protein Virulence vSa¥á Protein 1e-141 99
SACOL0470 YP_185360.1 superantigen-like protein Virulence vSa¥á Protein 9e-138 98
set3nm YP_001331424.1 superantigen-like protein Virulence vSa¥á Protein 9e-138 98
SAUSA300_0397 YP_493111.1 superantigen-like protein Virulence vSa¥á Protein 9e-138 98
set8 NP_370948.1 superantigen-like protein Virulence vSa¥á Protein 8e-140 97
set8 NP_373634.1 superantigen-like protein Virulence vSa¥á Protein 8e-140 97
SAKOR_00406 YP_008490590.1 Exotoxin Virulence vSa¥á Protein 1e-136 95
SAR0425 YP_039877.1 superantigen-like protein Not tested vSa¥á Protein 1e-90 65
SAMSHR1132_03740 YP_005324896.1 exotoxin Virulence vSa¥á Protein 9e-88 64
SAR0424 YP_039876.1 superantigen-like protein Virulence vSa¥á Protein 5e-84 56