Gene Information

Name : set16 (MW0382)
Accession : NP_645199.1
Strain : Staphylococcus aureus MW2
Genome accession: NC_003923
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 429229 - 429909 bp
Length : 681 bp
Strand : +
Note : exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence : 
ATGAAATTTAAAGCGATAGCAAAAGCAAGTTTAGCATTGGGAATGTTAGCAACAGGTGTAATTACATCGAATGTACAATC
AGTACAAGCGAAAACAGAAGTTAAACAACAAAGTGAGGCTGATTTAAAACTTTATTATAATGGACCAAGTTTTGAATATA
AAAAAGTAACTGGATATGGATTTATTGAAGGTAAAGATAGATTTATTGATTTTATATACAATGGACAATATAATAAAATA
TCTTTAGTTGGTTCTGATAAAGATAAATATAATGAAGAAGTTAACCCAGATATAGATGTGTTTGTCGTTAGAGAAGGAAA
CGGTAGACAAGCTGATAATCATTCGATTGGTGGCATAACAAAAACTAATAGAGGAGTGTATTATGACTATATACACACAC
CAATCCTTGAAATCAAGAAAGGTAAAGAAGAACCACAAAGTAGTCTATACCAAATTTATAAAGAAGACATCTCACTAAAA
GAACTTGATTTTAAATTAAGAAAGCAATTAATTAGTCAAAGTGGCTTGTATTCAAATGGTCTTAAACAAGGTCAAATTAC
AATTACAATGAATGATGGCACAACACATACAATCGATTTAAGTCAAAAACTTGAAAAAGAACGTATGGGCGAGTCTATCG
ATGGCAGACAAATACAAAAAATTCTAGTAGAAATGAAATAA

Protein sequence : 
MKFKAIAKASLALGMLATGVITSNVQSVQAKTEVKQQSEADLKLYYNGPSFEYKKVTGYGFIEGKDRFIDFIYNGQYNKI
SLVGSDKDKYNEEVNPDIDVFVVREGNGRQADNHSIGGITKTNRGVYYDYIHTPILEIKKGKEEPQSSLYQIYKEDISLK
ELDFKLRKQLISQSGLYSNGLKQGQITITMNDGTTHTIDLSQKLEKERMGESIDGRQIQKILVEMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0384 YP_042509.1 superantigen-like protein Virulence vSa¥á Protein 4e-102 100
set16 NP_645199.1 superantigen-like protein Virulence vSa¥á Protein 4e-102 100
SAR0422 YP_039874.1 superantigen-like protein Virulence vSa¥á Protein 2e-97 93
set6 NP_370946.1 superantigen-like protein Virulence vSa¥á Protein 4e-78 77
set6 NP_373632.1 superantigen-like protein Virulence vSa¥á Protein 4e-78 77
SAMSHR1132_03720 YP_005324894.1 exotoxin Virulence vSa¥á Protein 3e-71 71
SACOL0468 YP_185358.1 superantigen-like protein Virulence vSa¥á Protein 2e-68 69
set1nm YP_001331422.1 superantigen-like protein Virulence vSa¥á Protein 2e-68 69
SAUSA300_0395 YP_493109.1 superantigen-like protein Virulence vSa¥á Protein 2e-68 69
SAKOR_00404 YP_008490588.1 Exotoxin Virulence vSa¥á Protein 1e-68 68
SAKOR_00417 YP_008490601.1 Exotoxin Not tested vSa¥á Protein 2e-42 49
set15 NP_370957.1 superantigen-like protein Virulence vSa¥á Protein 3e-42 48
set15 NP_373644.1 superantigen-like protein Virulence vSa¥á Protein 3e-42 48
SACOL0478 YP_185368.1 superantigen-like protein Virulence vSa¥á Protein 7e-40 47
set11nm YP_001331434.1 superantigen-like protein Virulence vSa¥á Protein 7e-40 47
SAUSA300_0407 YP_493121.1 superantigen-like protein Virulence vSa¥á Protein 7e-40 47
SAR0435 YP_039886.1 superantigen-like protein Virulence vSa¥á Protein 1e-43 46
SAS0396 YP_042522.1 superantigen-like protein Virulence vSa¥á Protein 1e-42 45
SAMSHR1132_03810 YP_005324902.1 exotoxin Virulence vSa¥á Protein 7e-33 45
set26 NP_645211.1 superantigen-like protein Virulence vSa¥á Protein 1e-42 45
set3 YP_039879.1 superantigen-like protein 5 Virulence vSa¥á Protein 5e-38 44
set5nm YP_001331426.1 superantigen-like protein 5 Virulence vSa¥á Protein 5e-39 43
SAUSA300_0399 YP_493113.1 superantigen-like protein 5 Virulence vSa¥á Protein 5e-39 43
set10 NP_370949.1 superantigen-like protein 5 Virulence vSa¥á Protein 9e-39 43
set10 NP_373636.1 superantigen-like protein 5 Virulence vSa¥á Protein 9e-39 43
SAS0388 YP_042513.1 superantigen-like protein 5 Virulence vSa¥á Protein 6e-39 43
set20 NP_645203.1 superantigen-like protein 5 Virulence vSa¥á Protein 6e-39 43
SAKOR_00409 YP_008490593.1 Exotoxin Virulence vSa¥á Protein 2e-39 43
SAMSHR1132_03750 YP_005324897.1 exotoxin 3 Virulence vSa¥á Protein 9e-36 42
SAR0425 YP_039877.1 superantigen-like protein Not tested vSa¥á Protein 2e-25 41