Gene Information

Name : azi; div (MW2570)
Accession : NP_647387.1
Strain : Staphylococcus aureus MW2
Genome accession: NC_003923
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 2749674 - 2752064 bp
Length : 2391 bp
Strand : -
Note : preprotein translocase secA homolog; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of Sec

DNA sequence :
ATGAAACATAAACTAGATGTTACGATAAACGAATTAAGACTAAAGTCGATTAGAAAAATAGTGAAACGCATCAATACATG
GGGCGATGAAGTTAAATCATATTCTGATGATGCGTTAAAACAAAAGACAATAGAATTTAAAGAACGTTTAGCATCAGGAG
TTGATACACTAGATACATTGTTACCTGAAGCTTATGCAGTGGCACGTGAAGCGAGCTGGAGAGTATTAGGTATGTATCCT
AAAGAAGTTCAGTTAATCGGAGCGATTGTATTGCATGAAGGTAACATTGCGGAGATGCAAACAGGCGAAGGTAAAACATT
AACAGCAACGATGCCTTTATATTTAAATGCACTTTCGGGAAAAGGAACATATTTAATTACAACGAATGATTATTTAGCGA
AGCGTGATTTTGAAGAGATGCAACCATTATATGAATGGTTAGGTTTAACTGCTTCATTAGGTTTTGTTGATATTGTGGAT
TATGAGTATCAAAAAGGGGAAAAACGTAATTTATATGAACATGATATTATATATACAACTAATGGACGTCTCGGTTTTGA
TTATTTAATTGATAATTTGGCTGATAGTGCGGAAGGGAAATTTTTACCACAATTAAATTACGGTATTATTGATGAAGTGG
ACTCAATCATTTTAGATGCTGCGCAAACACCATTAGTTATTTCGGGCGCACCAAGATTACAATCAAATCTATTTCATATT
GTGAAAGAGTTTGTAGATACATTGATTGAAGACGTGCATTTTAAAATGAAGAAGACCAAAAAAGAAATATGGCTGTTAAA
TCAAGGTATTGAAGCGGCACAATCATACTTTAATGTTGAAGATTTATATAGCGAACAAGCGATGGTCCTAGTGCGTAATA
TTAATCTAGCACTGCGCGCGCAATATTTGTTTGAATCTAATGTCGATTACTTTGTATATAATGGTGATATTGTTTTAATT
GACCGTATTACAGGTCGTATGTTACCGGGAACTAAGTTGCAAGCTGGACTTCACCAAGCTATTGAAGCGAAAGAAGGTAT
GGAGGTTTCAACAGATAAAAGTGTTATGGCAACAATTACCTTCCAGAATTTATTTAAACTTTTTGAATCATTTTCAGGTA
TGACAGCTACAGGAAAATTAGGCGAATCAGAGTTCTTTGATTTGTATTCAAAAATAGTCGTACAAGTACCAACTGATAAA
GCGATTCAACGTATCGATGAACCAGATAAAGTGTTTCGTTCAGTTGATGAGAAAAACATCGCGATGATTCATGATATAGT
TGAACTTCATGAAACGGGGCGACCGGTTTTACTCATAACGAGAACTGCTGAAGCGGCTGAATACTTTTCGAAAGTATTAT
TCCAAATGGATATTCCTAATAATTTACTCATTGCGCAAAATGTTGCAAAAGAAGCGCAGATGATAGCTGAAGCAGGGCAA
ATTGGTTCCATGACTGTTGCGACTAGTATGGCAGGTCGAGGCACAGATATTAAACTTGGTGAAGGTGTCGAAGCATTAGG
TGGATTAGCTGTTATTATTCATGAACATATGGAAAATAGCCGTGTAGACAGGCAATTACGTGGTCGTTCTGGTAGACAAG
GGGATCCGGGATCATCTTGTATATATATTTCACTAGATGATTATTTAGTTAAGCGATGGAGCGATAGTAATTTAGCGGAA
AATAATCAATTATATTCATTAGATGCACAACGATTATCGCAAAGTAATTTGTTTAATCGCAAAGTTAAGCAAATTGTAGT
TAAAGCGCAGCGTATCTCGGAAGAACAAGGGGTTAAAGCTCGTGAAATGGCTAATGAATTTGAAAAAAGCATTAGTATAC
AGCGAGATCTTGTATACGAGGAACGCAATCGAGTTTTAGAAATAGATGATGCTGAGAATCAAGATTTTAAAGCGTTAGCT
AAAGATGTATTTGAAATGTTTGTAAATGAGGAAAAGGTGCTAACAAAATCGCGTGTTGTCGAGTATATTTATCAAAATTT
AAGTTTCCAATTTAATAAAGATGTGGCTTGTGTTAATTTTAAAGATAAGCAAGCAGTAGTGACATTTTTATTAGAGCAAT
TTGAAAAGCAATTAGCTTTGAATCGTAAAAACATGCAAAGTGCATATTATTATAATATTTTCGTTCAAAAAGTCTTTTTG
AAAGCAATTGATTCATGTTGGTTAGAACAAGTCGACTATTTACAACAATTAAAAGCAAGCGTTAATCAACGACAAAATGG
GCAACGTAACGCTATTTTTGAATACCATAGAGTTGCATTAGATTCATTTGAAGTTATGACACGAAATATCAAAAAAAGAA
TGGTGAAAAATATTTGTCAAAGCATGATTACATTTGATAAAGAGGGTATGCCAGTTATACATTTTCCATAA

Protein sequence :
MKHKLDVTINELRLKSIRKIVKRINTWGDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYP
KEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVD
YEYQKGEKRNLYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHI
VKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLI
DRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDK
AIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQ
IGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAE
NNQLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENQDFKALA
KDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFL
KAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 7e-155 46