Gene Information

Name : MW2367 (MW2367)
Accession : NP_647184.1
Strain : Staphylococcus aureus MW2
Genome accession: NC_003923
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 2520089 - 2521024 bp
Length : 936 bp
Strand : -
Note : hypothetical protein, similar to 2-dehydropantoate 2-reductase; ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATTGCAATTGCTGGATCGGGTGCATTAGGTAGTGGCTTTGGTGCCAAACTATTTCAAGCAGGATATGATGTCAC
ACTTATTGACGGATATACATCTCATGTTGAAGCGGTTAAGCAACATGGATTAAATATAACGATTAATGGAGAGGCATTCG
AGTTAAACATTCCGATGTATCATTTTAATGATCAACCGGACGAAAGCATTTACGATGTTGTCTTTCTATTTCCAAAGTCT
ATGCAATTAAAAGAAGTGATGGAAGATATGAAGCCACATATTGATAATGAAACGATCGTCGTATGTACGATGAATGGTCT
GAAGCATGAAGAAGTCATTGCGCAGTATGTTGCTCAATCACAAATTGTCAGAGGTGTTACGACTTGGACGGCAGGTCTTG
AAAGCCCTGGACACAGTCATTTACTTGGTAGTGGACCAGTTGAAATAGGTGAACTAGTGGATGAAGGTAAAGAAAATGTT
ATAAAAGTTGCTGATTTACTTAACGAAGCGGAATTGAATGGTGTCATTAGTAAAGATTTATACCAATCGATTTGGAAAAA
GATTTGTGTTAATGGTACGGCAAATGCATTAAGCACAGTGTTGGAGTGTAATATGGCATCGCTGAATGAAAGTAGTTATG
CGAAGTGTTTGATTTATAAATTAACGCAAGAAATAGTGCATGTAGCGACGATTGATAATGTTCATTTAAATGTTGATGAA
GTATTTGAATATTTAGTTGATTTAAATGAAAAAGTTGGTGCGCATTATCCATCCATGTATCAAGATTTAATTGTTAATAA
TAGAAAAACTGAAATTGATTATATTAATGGCGCAGTTGCAACATTGGGTAAACAACGTCATATTGAAGCGCCAGTCAATC
GCTTTATTACTGATTTAATTCATACTAAAGAAAGTCAGCGACACGCACAGGATTAA

Protein sequence :
MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGLNITINGEAFELNIPMYHFNDQPDESIYDVVFLFPKS
MQLKEVMEDMKPHIDNETIVVCTMNGLKHEEVIAQYVAQSQIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENV
IKVADLLNEAELNGVISKDLYQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLIYKLTQEIVHVATIDNVHLNVDE
VFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYINGAVATLGKQRHIEAPVNRFITDLIHTKESQRHAQD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 7e-49 42
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 5e-49 42