Gene Information

Name : hlgA (MW2342)
Accession : NP_647159.1
Strain : Staphylococcus aureus MW2
Genome accession: NC_003923
Putative virulence/resistance : Virulence
Product : gamma-hemolysin chain II precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2491405 - 2492334 bp
Length : 930 bp
Strand : +
Note : -

DNA sequence :
ATGATTAAAAATAAAATATTAACAGCAACTTTAGCAGTTGGTTTAATAGCCCCTTTAGCCAATCCATTTATAGAAATTTC
TAAAGCAGAAAATAAGATAGAAGATATCGGCCAAGGTGCAGAAATCATCAAAAGAACACAAGACATTACTAGCAAACGAT
TAGCTATAACTCAAAACATTCAATTTGATTTTGTAAAAGATAAAAAATATAACAAAGATGCCCTAGTTGTTAAGATGCAA
GGCTTCATCAGCTCTAGAACAACATATTCAGACTTAAAAAAATATCCATATATTAAAAGAATGATATGGCCATTTCAATA
TAATATCAGTTTGAAAACGAAAGACTCTAATGTTGATTTAATCAATTATCTTCCTAAAAATAAAATTGATTCAGCAGATG
TTAGTCAGAAATTAGGCTATAATATCGGCGGAAACTTCCAATCAGCGCCATCAATCGGAGGCAGTGGCTCATTCAACTAC
TCTAAAACAATTAGTTATAATCAAAAAAACTATGTTACTGAAGTAGAAAGTCAGAACTCTAAAGGTGTTAAATGGGGAGT
TAAAGCAAATTCATTCGTTACACCGAATGGTCAAGTATCTGCATATGATCAATACTTATTTGCACAAGACCCAACTGGTC
CAGCAGCAAGAGACTATTTCGTCCCAGATAATCAATTACCTCCTTTAATTCAAAGTGGCTTTAATCCATCATTTATTACA
ACATTGTCACACGAAAGAGGTAAAGGTGATAAAAGCGAGTTTGAAATCACTTACGGCAGAAACATGGATGCTACATATGC
TTACGTGACAAGACATCGTTTAGCCGTTGATAGAAAACATGATGCTTTTAAAAACCGAAACGTTACAGTTAAATATGAAG
TGAACTGGAAAACACATGAAGTAAAAATTAAAAGCATCACACCTAAGTAA

Protein sequence :
MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQ
GFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNY
SKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFIT
TLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 7e-106 71
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 7e-106 71
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 7e-106 71
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 7e-106 71
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 7e-106 71
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 7e-106 71
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 6e-106 71
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 5e-95 66
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 5e-95 66
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 5e-98 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlgA NP_647159.1 gamma-hemolysin chain II precursor VFG1273 Protein 8e-142 100
hlgA NP_647159.1 gamma-hemolysin chain II precursor VFG1274 Protein 5e-90 68
hlgA NP_647159.1 gamma-hemolysin chain II precursor VFG1277 Protein 2e-95 66