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Name : leuS (MW1701) Accession : NP_646518.1 Strain : Staphylococcus aureus MW2 Genome accession: NC_003923 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1853980 - 1856403 bp Length : 2424 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGTTGAATTACAACCACAATCAAATTGAAAAGAAATGGCAAGACTATTGGGACGAAAATAAAACATTTAAAACAAATGA TAACTTAGGTCAAAAGAAATTTTATGCTTTAGACATGTTTCCATATCCATCAGGTGCTGGTTTACATGTTGGACATCCTG AGGGCTATACAGCAACAGATATCATTTCAAGATATAAAAGAATGCAAGGATATAATGTATTACATCCGATGGGGTGGGAT GCATTCGGATTACCAGCAGAGCAATATGCTTTAGACACTGGCAACGACCCACGTGAATTTACAAAGAAAAATATCCAAAC TTTTAAACGACAAATTAAAGAATTAGGGTTCAGTTATGATTGGGATCGTGAAGTTAATACAACAGATCCAGAATACTATA AATGGACACAGTGGATTTTCATACAGTTATATAACAAAGGTTTAGCATACGTTGATGAAGTTGCAGTTAACTGGTGTCCA GCATTAGGCACTGTTTTATCTAACGAAGAAGTGATTGATGGTGTCTCTGAACGTGGTGGACATCCAGTTTATCGTAAGCC GATGAAACAATGGGTACTTAAAATCACAGAATATGCAGATCAATTATTAGCAGATTTAGATGATTTAGATTGGCCTGAAT CTTTAAAAGATATGCAGCGCAATTGGATTGGACGTTCTGAAGGGGCCAAAGTTTCATTTGATGTAGATAATACGGAAGCG GAAGGAAAAGTAGAAGTATTTACGACTAGACCAGATACAATCTATGGTGCATCATTCTTAGTCTTAAGTCCTGAACATGC ATTAGTTAATTCAATTACAACTGATGAATATAAAGAAAAAGTAAAAGCTTATCAAACAGAAGCTTCTAAAAAGTCAGATT TAGAACGTACAGATTTAGCAAAAGATAAATCAGGTGTGTTTACTGGTGCATATGCAATTAATCCTTTATCTGGTGAAAAA GTACAAATTTGGATTGCTGATTATGTATTATCAACATATGGTACTGGAGCAATTATGGCAGTACCAGCGCATGATGACAG AGATTATGAATTTGCTAAAAAGTTTGATTTGCCAATCATTGAAGTCATCGAAGGTGGAAATGTTGAAGAAGCAGCATACA CTGGTGAAGGTAAACATATTAATTCTGGTGAACTTGATGGTTTAGAAAATGAAGCGGCAATTACTAAAGCTATTCAATTA TTAGAGCAAAAAGGTGCTGGCGAAAAGAAAGTTAATTACAAATTAAGAGATTGGTTATTCAGTCGTCAGCGTTATTGGGG CGAACCAATTCCTGTCATTCATTGGGAAGATGGAACAATGACAACTGTTCCTGAAGAAGAGCTACCATTGTTGTTACCTG AAACAGATGAAATCAAGCCATCAGGGACTGGTGAGTCTCCACTAGCTAATATTGATTCATTTGTAAATGTTGTAGATGAA AAAACAGGTATGAAAGGACGTCGTGAAACAAATACAATGCCACAATGGGCAGGTAGTTGTTGGTATTATTTACGTTACAT CGATCCTAAAAATGAAAATATGTTAGCAGATCCTGAAAAATTAAAACATTGGTTACCTGTTGATTTATATATCGGTGGAG TAGAACATGCGGTTCTTCACTTATTATATGCAAGATTTTGGCATAAAGTCCTTTATGATTTGGGTATCGTACCTACTAAA GAACCTTTCCAAAAATTATTTAACCAAGGTATGATTTTAGGAGAAGGTAATGAGAAGATGAGTAAATCTAAAGGAAATGT AATCAATCCTGATGATATAGTACAGTCTCATGGTGCAGATACTTTACGTCTTTACGAAATGTTTATGGGACCTTTAGATG CTGCAATTGCATGGAGTGAAAAAGGATTAGATGGGTCTCGTCGATTCTTAGATCGCGTATGGCGTTTAATGGTAAATGAA GATGGAACATTGAGTTCAAAAATTGTAACTACAAATAATAAATCTTTAGATAAAGTTTATAACCAAACTGTTAAAAAGGT AACAGAAGACTTTGAAACATTAGGATTTAATACTGCTATTAGTCAATTAATGGTATTTATTAATGAGTGTTATAAAGTTG ATGAAGTTTATAAACCTTACATTGAAGGCTTCGTTAAAATGTTAGCACCTATTGCACCACATATCGGTGAAGAATTATGG TCAAAATTAGGACATGAAGAGTCTATTACGTACCAACCTTGGCCAACTTATGACGAAGCACTACTTGTAGATGATGAAGT AGAAATCGTTGTTCAAGTAAATGGTAAATTGAGAGCTAAAATTAAAATTGCTAAAGATACATCAAAAGAAGAAATGCAAG AAATTGCCTTATCTAATGACAATGTTAAAGCGAGTATTGAAGGTAAAGACATCATGAAAGTCATCGCTGTTCCTCAAAAA TTAGTCAATATTGTAGCTAAATAA Protein sequence : MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWD AFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCP ALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEA EGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYAINPLSGEK VQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQL LEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDE KTGMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGIVPTK EPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNE DGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELW SKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQK LVNIVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 0.0 | 66 |
