Gene Information

Name : lukS (MW1379)
Accession : NP_646196.1
Strain : Staphylococcus aureus MW2
Genome accession: NC_003923
Putative virulence/resistance : Virulence
Product : Panton-Valentine leukocidin chain S precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1530360 - 1531298 bp
Length : 939 bp
Strand : -
Note : -

DNA sequence : 
ATGGTCAAAAAAAGACTATTAGCTGCAACATTGTCGTTAGGAATAATCACTCCTATTGCTACTTCGTTTCATGAATCTAA
AGCTGATAACAATATTGAGAATATTGGTGATGGCGCTGAGGTAGTCAAAAGAACAGAAGATACAAGTAGCGATAAGTGGG
GGGTCACACAAAATATTCAGTTTGATTTTGTTAAAGATAAAAAGTATAACAAAGACGCTTTGATTTTAAAAATGCAAGGT
TTTATCAATTCAAAGACTACTTATTACAATTACAAAAACACAGATCATATAAAAGCAATGAGGTGGCCTTTCCAATACAA
TATTGGTCTCAAAACAAATGACCCCAATGTAGATTTAATAAATTATCTACCTAAAAATAAAATAGATTCAGTAAATGTTA
GTCAAACATTAGGTTATAACATAGGTGGTAATTTTAATAGTGGTCCATCAACAGGAGGTAATGGTTCATTTAATTATTCA
AAAACAATTAGTTATAATCAACAAAACTATATCAGTGAAGTAGAACGTCAAAATTCAAAAAGTGTTCAATGGGGAATAAA
AGCTAATTCATTTATCACATCATTAGGTAAAATGTCTGGACATGATCCAAATTTATTTGTTGGATATAAACCATATAGTC
AAAATCCGAGAGACTATTTTGTTCCAGACAATGAATTACCCCCATTAGTACACAGTGGTTTCAATCCTTCATTTATTGCA
ACTGTTTCTCATGAAAAAGGCTCAGGAGATACAAGTGAATTTGAAATAACGTATGGCAGAAATATGGATGTTACTCATGC
TACTAGAAGAACAACACACTATGGCAATAGTTATTTAGAAGGATCTAGAATACACAACGCATTTGTAAACAGAAATTACA
CAGTTAAATATGAAGTGAACTGGAAAACTCATGAAATTAAAGTGAAAGGACATAATTGA

Protein sequence : 
MVKKRLLAATLSLGIITPIATSFHESKADNNIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQG
FINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPSTGGNGSFNYS
KTISYNQQNYISEVERQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIA
TVSHEKGSGDTSEFEITYGRNMDVTHATRRTTHYGNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 4e-143 100
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 4e-143 100
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 5e-101 69
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 5e-101 69
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 5e-101 69
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 5e-101 69
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 5e-101 69
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 5e-101 69
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 6e-101 69
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 6e-96 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor VFG1277 Protein 2e-143 100
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor VFG1274 Protein 6e-116 78
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor VFG1273 Protein 2e-95 66