Gene Information

Name : guaA (XAC2287)
Accession : NP_642604.1
Strain : Xanthomonas axonopodis 306
Genome accession: NC_003919
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2675443 - 2677008 bp
Length : 1566 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCAACATCCATACCGACAAGATCCTCATCCTCGATTTCGGCGCGCAGTACACCCAGCTGATTGCGCGGCGTATCCG
CGAGATCGGGGTCTATTGCGAGATCTGGGCATGGGATCACGATCCGTCGGAGATTGCCGGTTTCGGTGCCAAGGGCATCA
TCCTGTCCGGCGGCCCGGAGTCGACCACGTTGCCTGGCGCACCGGTCGCGCCGCAGGAAGTGTTCGATAGCGGCCTGCCG
GTGTTCGGTATCTGCTACGGCATGCAGACGCTCGCCGCGCAGTTGGGTGGTGCCACCGAAGCCGCCGATCAGCGCGAATT
CGGCCATGCCGAAGTGGATGTGGTGGCGGCAGATGCCTTGTTCGCTGGCCTCACCGACCATGCCGGCGCTTCGCGCCTGA
ATGTATGGATGAGCCATGGCGACCACGTGTCGCAGGTGCCGCCGGGCTTCACCATTACCGCCACGACCGACCGCATCCCG
GTGGCGGCCATGTCCAACGAAGCCAAGCGCTGGTACGGCGTGCAGTTCCATCCGGAGGTGACGCATACCTTGCAGGGCCA
GACCTTGCTGCGTCGCTTCGTGGTGGATGTCTGCGGCTGCCAGACACTGTGGACTGCGGCCAACATCATCGAGGACCAGA
TCGCGCGCGTGCGCGAACAGGTGGGCGACGACGAAGTGATTCTCGGGCTGTCCGGCGGCGTCGATTCGTCGGTGGTTGCC
GCGCTGCTGCACAAGGCGATCGGCGACAAGCTCACTTGTGTGTTCGTCGATACCGGCTTGCTGCGTTGGCAGGAAGGCGA
CCAGGTGATGGCGATGTTCGCCGAGCACATGGGCGTCAAGGTGATCCGCGTCAACGCGGCCGACCGCTATTTCGCCAAGC
TGGAAGGCGTGCGCGACCCGGAAGCCAAGCGCAAGATCATCGGCAACCTGTTCGTGGAGATCTTCGACGAAGAATCCAAC
AAGCTGGCCAATGCCAAGTGGCTGGCGCAGGGCACGATCTATCCGGACGTGATCGAGTCGGCCGGCAGCAAGACCGGCAA
GGCGCACGTGATCAAGAGCCACCATAACGTCGGCGGCCTGCCCGAGCATATGAAGCTGGGCCTGGTCGAGCCGCTGCGCG
AACTGTTCAAGGACGAAGTGCGGCGCCTGGGCGTGGAGCTCGGCCTGCCGCGCACCATGGTGTATCGCCATCCGTTCCCG
GGCCCTGGCCTGGGCGTGCGCATCCTCGGCGAAGTCAAGCGCGAGTACGCCGAGCTGCTGGCCAAGGCCGATGCGATCTT
CATCGACGAACTGCGCAAGGCCGACCTGTACGACACCACCAGCCAGGCGTTCGCGGTGTTCCTGCCGGTCAAGTCGGTGG
GCGTGGTCGGCGACGCGCGCGCCTACGAATGGGTGATCGCACTGCGCGCGGTGGAAACCATCGATTTCATGACCGCGCAC
TGGGCGCACCTGCCGTACGACTTCCTCGGCACGGTGAGCAACCGCATCATCAACGAACTGCGCGGCGTTTCGCGGGTGGT
CTACGACATCTCCGGCAAGCCGCCGGCGACGATCGAGTGGGAGTGA

Protein sequence :
MTNIHTDKILILDFGAQYTQLIARRIREIGVYCEIWAWDHDPSEIAGFGAKGIILSGGPESTTLPGAPVAPQEVFDSGLP
VFGICYGMQTLAAQLGGATEAADQREFGHAEVDVVAADALFAGLTDHAGASRLNVWMSHGDHVSQVPPGFTITATTDRIP
VAAMSNEAKRWYGVQFHPEVTHTLQGQTLLRRFVVDVCGCQTLWTAANIIEDQIARVREQVGDDEVILGLSGGVDSSVVA
ALLHKAIGDKLTCVFVDTGLLRWQEGDQVMAMFAEHMGVKVIRVNAADRYFAKLEGVRDPEAKRKIIGNLFVEIFDEESN
KLANAKWLAQGTIYPDVIESAGSKTGKAHVIKSHHNVGGLPEHMKLGLVEPLRELFKDEVRRLGVELGLPRTMVYRHPFP
GPGLGVRILGEVKREYAELLAKADAIFIDELRKADLYDTTSQAFAVFLPVKSVGVVGDARAYEWVIALRAVETIDFMTAH
WAHLPYDFLGTVSNRIINELRGVSRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-126 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-126 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-126 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-112 50