Gene Information

Name : hemC (CJE0649)
Accession : YP_178664.1
Strain : Campylobacter jejuni RM1221
Genome accession: NC_003912
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 585744 - 586667 bp
Length : 924 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAAGCTTATTATTGCAACAAGAAAAAGTCAATTAGCTCTTTGGCAAAGTGAACATGTAGCCCAAATTTTAAAAAATAC
ACATCAAATTGAAGTGCTTTTAGAAGGTTTTAAAACAAAAGGCGATGTTTTGCTTGATTCTCCTTTGGCAAAAATTGGTG
GTAAAGGACTTTTTACAAAAGAACTTGAAGAAAGTATGTTAAGAAAAGAAGCACACTTAGCGGTGCATAGTTTAAAAGAT
GTGCCTAGTTTTTTTCCTCAAGGTTTAGTTTTGGCAGCGGTAAGTAAAAGAGAGCAAAGCAATGATGCTATGCTAAGTCA
AAATTATAAAGATTTTCTTTCTTTGCCAAAAGGTGCAAAAATAGGCACTACTAGTCTTAGACGCAAGATGCAGCTTTTAT
TATTAAGACCTGATTTAGATATTATTTCTTTGCGTGGTAATGTCAATTCTCGTATAGAGAAATTAAAAAATAATGATTTT
GATGCGATTATTTTGGCAATGGCGGGAATTAAACGCTTAAACTTAGATAAGCAAGTGAATTTTGTTTATGAATTTAGCAA
AGATGAGCTTATTCCTGCGGCTTCTCAAGGAGCTTTAGGTATAGAAAGCATAAATGATGAAAAAATTTTAGAACTTTTAA
AATGTTTAAATGATGAAAATGCTTTGATTGAAACAAGCATTGAAAGAGAATTTATTGCTACTTTAGAAGGAGGTTGTCAA
GTTCCTATAGGTATTAACGCAGAGCTCTTGGGAGATGAAATTTGTGTGCGTGCGGTACTTGGACTACCCGATGGAAGTGA
AATTTTAAAAGATAAGAGAATGATTAAAAAGAATGATTTTAAAGGTTTTGGAGAGAGTTTGGCTAAGGAGTTTATTGCTA
AAGGTGCTAAAGAACTTTTAAAAAAAGCTGAGAGTATGATATGA

Protein sequence : 
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTKELEESMLRKEAHLAVHSLKD
VPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAKIGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDF
DAIILAMAGIKRLNLDKQVNFVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELLKKAESMI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-54 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-54 48