Gene Information

Name : lysS (CJE0450)
Accession : YP_178469.1
Strain : Campylobacter jejuni RM1221
Genome accession: NC_003912
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 403402 - 404907 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTTGATAATATTTTAGAGCAGCAAAGAATAGAAAAAGCTAAAGAGTTAAAAAATTTAGGGATTAATCCTTATCCTCA
TTTTTTAGAAAAGGAAATGTCTTTAAAGACTTTTAAGGATAGATTTTCTTATATTTTAGAGCAAGTTGAAAAAAGAGATG
AAAGTGTCAATGCTGTTGTTGCAGGACGTTTGAAACTTTTGCGTATAGCTGGGAAATCAATTTTTGCAAACATTGAAGAT
GAGGATACAAATTTACAAATTTATTTTAGTAAAGATAGCGTAGGCGAAGAGCTTTATACGATTTTAAAAAAGAATTTAGA
GGTGGGTGATATTGTTTTGGTTAAAGGTTTTCCTTTTGTAACTAAAACAGGTGAGTTTAGTTTGCATGCAAGTGAAGTAA
AACTCGCTACAAAAGCTATTGTTCCTTTACCTGAAAAATATCATGGATTAACAGATATTGAACAAAGATATCGTAAACGT
TATGTTGATATGATAATGAATGCAGAAGTTAGAAAAGATTTTTTAGTGCGTTCTAAAGTGGTGAGTTTGATTCGTCATTT
TTTTGAAAATAAAGGCTTTTTAGAAGTAGAAACTCCTATGATGCATCCGATTGCAGGTGGAGCAAACGCTAAGCCTTTTG
TAACTTTTCACAATTCTTTAGGCGTAGAAAGATTTTTAAGAATTGCTCCAGAACTTTATCTTAAAAGACTTGTAGTGGGT
GGTTTTGAGGCAGTTTTTGAAATCAATCGTTGTTTTAGAAACGAAGGTATGGATTTAACTCATAATCCCGAATTTACAAC
TATAGAATTTTATTGGGCTTATCATAATTATAAAGATTTAATGGATTTAACTGAAGAACTTTTTGCTTTGCTTTTAGATA
AACTTAATTTGGGAAAAACAATAGAATTTGATGGAAAAATGATAGATTTTTCTAAACCTTTTGAAAGAATAACCTATAAA
GATGCACTTTGTAAGTATGGTGGTTTAGATAGGGATTTAATCGAAGATAAGGAAAAAATTCTTACTAAATTAAAAGCAGA
TGGTTTTGAAGCGAATGAAAAGCTTGAACTTGGACATTTGCAAGCTGAACTTTTTGACAATTATGTGGAAGAAAAATTGA
TCAATCCTACTTTTGTGATTGATTTTCCTATTTCCATAAGTCCTTTATCAAGACGTAGCGATGAGGATTCTCAGATTGCT
GAGAGATTTGAGTTGTTTATTTGTGGAAGAGAATTGGCAAATGGTTTTAATGAGCTTAATGATCCTCTTGATCAATATGA
GAGATTTTTAAAACAAATTGAAGCTAAAAATGCAGGCGATGAAGAGGCTTGCGAAATGGATGAAGATTTTGTAAATGCTT
TGGGTTATGGAATGCCTCCAACGGCAGGGCAGGGTATAGGCATAGATAGACTTGTTATGCTTTTGACAAATAAAAAATCT
ATTCGAGATGTGATATTGTTTCCTGCAATGCGTCCATTAAAATCAGAACTAAAGGAGAAAGAATGA

Protein sequence :
MFDNILEQQRIEKAKELKNLGINPYPHFLEKEMSLKTFKDRFSYILEQVEKRDESVNAVVAGRLKLLRIAGKSIFANIED
EDTNLQIYFSKDSVGEELYTILKKNLEVGDIVLVKGFPFVTKTGEFSLHASEVKLATKAIVPLPEKYHGLTDIEQRYRKR
YVDMIMNAEVRKDFLVRSKVVSLIRHFFENKGFLEVETPMMHPIAGGANAKPFVTFHNSLGVERFLRIAPELYLKRLVVG
GFEAVFEINRCFRNEGMDLTHNPEFTTIEFYWAYHNYKDLMDLTEELFALLLDKLNLGKTIEFDGKMIDFSKPFERITYK
DALCKYGGLDRDLIEDKEKILTKLKADGFEANEKLELGHLQAELFDNYVEEKLINPTFVIDFPISISPLSRRSDEDSQIA
ERFELFICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQGIGIDRLVMLLTNKKS
IRDVILFPAMRPLKSELKEKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-105 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_178469.1 lysyl-tRNA synthetase VFG1668 Protein 2e-105 48