Gene Information

Name : hemC (CPS_0074)
Accession : YP_266842.1
Strain : Colwellia psychrerythraea 34H
Genome accession: NC_003910
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 77468 - 78421 bp
Length : 954 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAATAACACTACAGTACGAATTGCCACGCGTAAAAGCGCCCTCGCCTTATGGCAAGCAGAATATGTTAAAGCGCAACT
TGAGCATTTTCATGACGGTATTAATGTTGAATTAGTGCCTATGACAACGAAAGGCGACATCATTTTAGACACGCCTTTAG
CCAAAGTCGGCGGTAAAGGTTTATTTGTTAAAGAGCTTGAAGTAGCAATGCTTGAAGACCGTGCTGATATTGCTGTTCAT
TCAATGAAAGATGTTCCTGTCGATTTTCCAGAAGGCTTAGGATTAGAAGTCATTTGTCCTCGTGAAGATCCCCGTGATGC
TTTTGTTTCTAATACCATCAAATCATTAAGTGATTTACCACAAGGCTCTATTGTTGGCACCTCAAGCTTACGCCGTCAGT
GTCAATTAAAAGCAAGCCGCCCTGATTTAGATATTCGTGATTTACGTGGCAATGTAAATACCCGCCTAAGAAAATTAGAT
GAAGGTCAGTACGACGCTATTATATTAGCCGCTGCAGGCCTAATTCGCTTAGAAATGAGCGAGCGTATTGCACAGTTTAT
CGAACCAGAAGAAATGCTTCCTGCAAATGGCCAAGGCGCTGTTGGCATTGAATGTCGTAATGATGATGCGACAATTAAAG
CCTTATTAGCACCATTAGAATGTGCTACCACCCGTATTCGTGTTCTTGCAGAACGTGCAATGAATAGAGCATTACAAGGC
GGTTGCCAGGTTCCTATCGGTAGCTATGGTGTTATTTCTGCTGATGGTAAAAATATCCACTTACGTGGCTTAGTTGGCTC
TGTCGATGGTAGTGAAATGATAGAAAGTGAAATCACCGGCCCTGTTGAAGAAGGTGAAGCGCTCGGCAATAAACTCGCGC
AAGAGTTACTAAGCCGAGGTGCAGATAAAATTTTACAGCAAGTTTATTCAGAAAATGATATCAAAAACAGCTAA

Protein sequence : 
MNNTTVRIATRKSALALWQAEYVKAQLEHFHDGINVELVPMTTKGDIILDTPLAKVGGKGLFVKELEVAMLEDRADIAVH
SMKDVPVDFPEGLGLEVICPREDPRDAFVSNTIKSLSDLPQGSIVGTSSLRRQCQLKASRPDLDIRDLRGNVNTRLRKLD
EGQYDAIILAAAGLIRLEMSERIAQFIEPEEMLPANGQGAVGIECRNDDATIKALLAPLECATTRIRVLAERAMNRALQG
GCQVPIGSYGVISADGKNIHLRGLVGSVDGSEMIESEITGPVEEGEALGNKLAQELLSRGADKILQQVYSENDIKNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-75 60
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-75 60