Gene Information

Name : topB (CPS_4792)
Accession : YP_271431.1
Strain : Colwellia psychrerythraea 34H
Genome accession: NC_003910
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 5077284 - 5079233 bp
Length : 1950 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
TTGAAACTCTATATTGCCGAAAAACCGAGTTTAGGTCGCGCTATTGCTGCCGCATTACCTAAGCCACAAAAAAACCATAA
AACACATATTGAGCTCGCTAACGGTGATGTGGTCAGTTGGTGTATCGGACACATTTTGGCGCAAGCAGATCCTGAAGACT
ATGATGCCGAATTAAAAAAATGGCGCATGGAAAGTTTGCCTATAGTGCCGCAGCAATGGCAATTAAAACCCATTGCTCGA
ACTCGCTCACAACTCACTGTCTTAAGAAAATTGGTGAAACAAGCCGATGAAATTATTCACGCAGGCGATCCCGACAGAGA
AGGTCAATTACTCGTTGATGAAGTGATTGATTACTTTAAATTATCCAAAACAAAAAAAGCTAACATTAAACGTCTGCTGA
TCAGCGATTTAAACTTACCTGCCGTTAAGCGAGCCCTTACGTCACTAAAACCTAATAGTGATTTTATGCCGTTATCTATT
TCTGCTTTAGCACGTTCACGCGCTGATTGGCTTTATGGTATTAACCTTACCCGTGCATATACATTGCAAGGGCAAAAAAC
CGGTTACAACTCGGTATTGTCCGTAGGTCGTGTGCAAACACCTTTGTTAGGTTTAGTGGTTAGACGTGAGCAAGAAATTT
CAGAATTTGTCAGTAAACCATTCTTCCAAGTTCAGGCTCATATTGCACTAAGTTCAAAGGACGCCGTCGCTTTTACAGCA
AAATGGCAACCAAGTGAAAACTGTCAACCATATTGCGATGAAGAAGGTCGAGTTTTGGTAAAAGCATTAGCAGAGAATGT
CGTTAAACGCATTGCTAACCAACCCGCAACAATCAGTAATATTGACAGTAACGAAAAACAACAAGCCGCCCCATTACCCT
TTAATTTATCGCAATTACAAATTAGTGCTGCTAAGCAGTTTTCTATGAATGCCAAGCTTGTGCTTGATGTTTGTCAGGCT
TTATATGAAAGACATAAACTGATTACTTACCCACGTTCAGATTGTCGGTATTTGCCTAAAGAGCAACTAAAGCAAGCAAG
TGGCATTGTTAATACACTCGCCAACTCATCATTACCTTGTAATAAACCCGCTCAAGGGGCAAATACTTCTTTTGTGAGTA
AAGCATGGAACGATAAAAAAATAACCGCCCATCATGCAATTATCCCTACCGAGAAATCACCTGAGAACATCAATTTAAAT
ACCTTTGAAAAAAATGTCTATTTACTGATTGTACGTCAATATTTAGTACAGTTTTATCCTGCCTATATTTTTCAGCAAAC
CAAAGTGGAATTATTAATTGCTGGCGGGAATTTTATGAGCCAAGCAAAAACAGAAAAACAACTGGGCTGGCAAGTCTTAT
TCCCAAAAAGTAATAAAACGAATAACCAAAGCAAGTTAGAACATGGGCAAGAACAAGAGCAAACATTGCCCCCTTTAACA
AAAGGGCAACTATTACATTGCCAACAAGGCGAATTAATAGAAAAACACACGTCACCGCCGCAATCTTTTACTGATGCAAC
GCTGCTCGGTGCCATGACCGGTATTTCCCGTTACGTCAATGATGCGGCCATTAAAAAAGTACTGAAAGAAACCGATGGTC
TGGGTACAGACGCTACTCGCGCCGGCATTATAGATTTACTTTTTAAACGCGGGTTTTTACAACGTCAAGGCAAAGCGATT
ACTGCAACGAAGGTTGGTGTTGCGTTAATCACCGCCCTGCCCACCATGGCTACTTTGCCAGATATGACAGCACAATGGGA
AGCAACACTCACAGCAATCAGTGAGAAAAATGCCAACTATCTAAGCTTTATGCAACCTTTAACAGTTATAGTCAATGAGA
TGGTACAAGGTGCCAGTCAGCAATCTTTTTCTGGTTTACCTAAGGTTGCTTTTAAGCCTAAACGCGGCAAACGAACATTT
CAGAAGAAAGCGGTAAAAAAAGCAAGTTAG

Protein sequence :
MKLYIAEKPSLGRAIAAALPKPQKNHKTHIELANGDVVSWCIGHILAQADPEDYDAELKKWRMESLPIVPQQWQLKPIAR
TRSQLTVLRKLVKQADEIIHAGDPDREGQLLVDEVIDYFKLSKTKKANIKRLLISDLNLPAVKRALTSLKPNSDFMPLSI
SALARSRADWLYGINLTRAYTLQGQKTGYNSVLSVGRVQTPLLGLVVRREQEISEFVSKPFFQVQAHIALSSKDAVAFTA
KWQPSENCQPYCDEEGRVLVKALAENVVKRIANQPATISNIDSNEKQQAAPLPFNLSQLQISAAKQFSMNAKLVLDVCQA
LYERHKLITYPRSDCRYLPKEQLKQASGIVNTLANSSLPCNKPAQGANTSFVSKAWNDKKITAHHAIIPTEKSPENINLN
TFEKNVYLLIVRQYLVQFYPAYIFQQTKVELLIAGGNFMSQAKTEKQLGWQVLFPKSNKTNNQSKLEHGQEQEQTLPPLT
KGQLLHCQQGELIEKHTSPPQSFTDATLLGAMTGISRYVNDAAIKKVLKETDGLGTDATRAGIIDLLFKRGFLQRQGKAI
TATKVGVALITALPTMATLPDMTAQWEATLTAISEKNANYLSFMQPLTVIVNEMVQGASQQSFSGLPKVAFKPKRGKRTF
QKKAVKKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-111 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-111 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-111 41