Gene Information

Name : argHA (CPS_0464)
Accession : YP_267222.1
Strain : Colwellia psychrerythraea 34H
Genome accession: NC_003910
Putative virulence/resistance : Unknown
Product : bifunctional argininosuccinate lyase/N-acetylglutamate synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0165
EC number : 2.3.1.1
Position : 463682 - 465619 bp
Length : 1938 bp
Strand : +
Note : catalyzes the formation of arginine from (N-L-arginino)succinate and the formation of N-acetylglutamate from glutamate and acetyl-CoA

DNA sequence :
ATGGCTTTATGGGGCGGCCGCTTTAAAGGCGAAGCTAGCGTACAATTTAAAAGATTTAACGACTCACTACCAGTGGATTA
CCGCATGGCAGTGCAAGACATTGTTGGTTCAATTGCTTGGGCAGGTGCTATTAATAGTGTTGGCGTAATAAGTGATGAAG
AGCACATACGTTTAGTGGCAGCACTTAATGAGTTAAAAGCGTCTGTTGAAGCCGATCCTGAGCAAATTTTGTTATCAGAT
GCGGAAGATATTCACAGTTGGGTGGAACTTCAGTTAATTGAAAAAACCGGTGATTTAGGTAAGAAGCTCCATACAGGTCG
TAGTCGTAATGACCAAGTAGCAACTGATTTAAAGCTGTGGTGTAAAGAAACTGGTGGCGATTTATTGTTTGCACTGGTGA
ATCTACAGCAAGCGATGATGAATTTAGCTGAACGTGAAAAAGATACTGTGTTACCGGGTTATACCCATCTTCAAAGAGCA
CAACCGGTTACTTTCGGTCATTGGTGTTTAGCGTATGTTGAAATGTTTAACCGTGATATTGGTCGTTTAAAAGATGCGCT
TTATCGTTTAGATGTTTCGCCATTAGGCTCTGGTGCTTTAGCAGGTACTGCTTATCCAATAGACCGTAATGCTTTAGCAC
ATAGCTTAGGTTTTAGAACGGCCACGATGAATAGCCTTGATGCTGTTTCTGATAGAGATCATGTTATTGAATTGTTGGCT
TCAGCCAGTATTTCGATGATGCATTTATCACGTTTTGCAGAAGATTTAATTTTCTATAATTCAGGTGAAGCTGGTTTTGT
AGAGATGAGTGACTTAGTTAGCTCTGGCTCCTCATTAATGCCACAGAAAAAAAATCCGGATGCGTGTGAATTAATTCGTG
GTAAATCAGGACGTGTTTTTGGTGCATTAACGGGCATGTTAACCACAATGAAAGCGTTGGCGCTTGCCTATAATAAAGAT
ATGCAAGAAGACAAAGAAGGTTTGTTTGACGCGCTTGATACGTGGCAAGAATGTATGGAAATGGCTGTGTTAGTTGCTGA
CGGTTTAAAAGTTAATCGTTCTCGTACATTGGCGGCGGCTCAACAAGGTTATGCCAATGCGACTGAGCTTGCTGATTATT
TAGTGGGTAAAGACATTCCGTTCCGTGAAGCACATCATATTGTTGGTGAAGTGGTATTAGCTGCCATCGATAAAGGTGTA
CCTTTAGAAGACTTAACCATAAGTCAACTGAAAGAGTTTAGTGATAAAATTGAGCAAGATGTTTATCAACACCTTTCAAT
TGAATCAACGCTTAATAAGCGTGAAGCGCTTGGTGGTACTTCACGTTCACAAGTTAAAAAAGCGCTGGCAACTACCCAGT
CTGGCAATGAAGCTATTTTAAATGAACAAGTTGTTGGCGCACCAGGAAAACAACGAATTGAAGGGGCACTTAAGCAAGTA
AAACAGCGCTTAAATGCACAACGCGCTGCAGCTATGTCTGTCCGTCGAGCCAGAATGTCTGATGTTGATTGTATCCATCA
ACTGACTAACTTTTGGGCTGATAAAGGTGAGATTTTACCTCGAACTCGTGACAACATAATCCATGATATCCAGAATTTCG
TCGTAGCTGAACTTGACGGTAATGTTGTTGGCACCGCATCGCTTTACATTTATCAAACAGGTTTAGCAGAAATACGCTCT
GTTGTTGTGCAAGATGATGCACAAAAGCAAGGTCAAGGTGAGGCGCTTGTTCAATATTTGTTAGAATTTGCTAATCAAAT
GGAATTAGAACAGATTATTGTTTTAACTTACATTCCTCAGTATTTTGAACAGCTTGGTTTTAACGTAATAGATAAGAACT
CGCTCGCCGATAATATCATTGAAGACAGTGAACCAAGCCCGCATAAAGATCCTGCTGATGAAGTAGCGATGGAATATATT
GTTGGTCAAAGTAAGTAG

Protein sequence :
MALWGGRFKGEASVQFKRFNDSLPVDYRMAVQDIVGSIAWAGAINSVGVISDEEHIRLVAALNELKASVEADPEQILLSD
AEDIHSWVELQLIEKTGDLGKKLHTGRSRNDQVATDLKLWCKETGGDLLFALVNLQQAMMNLAEREKDTVLPGYTHLQRA
QPVTFGHWCLAYVEMFNRDIGRLKDALYRLDVSPLGSGALAGTAYPIDRNALAHSLGFRTATMNSLDAVSDRDHVIELLA
SASISMMHLSRFAEDLIFYNSGEAGFVEMSDLVSSGSSLMPQKKNPDACELIRGKSGRVFGALTGMLTTMKALALAYNKD
MQEDKEGLFDALDTWQECMEMAVLVADGLKVNRSRTLAAAQQGYANATELADYLVGKDIPFREAHHIVGEVVLAAIDKGV
PLEDLTISQLKEFSDKIEQDVYQHLSIESTLNKREALGGTSRSQVKKALATTQSGNEAILNEQVVGAPGKQRIEGALKQV
KQRLNAQRAAAMSVRRARMSDVDCIHQLTNFWADKGEILPRTRDNIIHDIQNFVVAELDGNVVGTASLYIYQTGLAEIRS
VVVQDDAQKQGQGEALVQYLLEFANQMELEQIIVLTYIPQYFEQLGFNVIDKNSLADNIIEDSEPSPHKDPADEVAMEYI
VGQSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00328 YP_008211654.1 Argininosuccinate lyase Not tested AbaR26 Protein 3e-87 48
BJAB07104_00324 YP_008207789.1 Argininosuccinate lyase Not tested AbaR25 Protein 3e-87 48