Gene Information

Name : guaA (CPS_4241)
Accession : YP_270891.1
Strain : Colwellia psychrerythraea 34H
Genome accession: NC_003910
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 4468063 - 4469640 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCAAAGACATTCATGATCACCGCATACTAATTCTAGATTTTGGTTCACAATACACACAGTTAATTGCTCGTCGCGT
ACGTGAAATTGGCGTTTACTGTGAACTTTGGTCTTGGGATGTTACCGAAGAGCAAATTAAAGGTTTTAATCCAACAGGTA
TTATTCTTGCAGGTGGCCCAGAGTCAGTAACTGAAGCTAACTCTCCTCGTGCACCTGAATATGTATATACTGCTGGCGTA
CCTGTATTAGGTATTTGTTACGGTATGCAAACAATGGCTGAGCAGCTTGGCGGTGGCGTTGAAAGTTCAAGCCATAAAGA
GTTTGGTTATGCTGCTGTTGAATTGATTGCTCAATCTGCGTTATTTAACAAAGTTGAAGACAGTATTGGCGATAACGGTA
ATGCTTTACTTGACGTTTGGATGAGTCACGGCGATAAAGTGTCAGCTATTCCTGAAGGTTTTGTTACCGTTGCACAAACA
GCAAGTTGTGCTTATGGCGCAATGGCTAATGAAGAAAAACAATTCTACGGCGTACAATTTCACCCAGAAGTAACACATAC
TAAACAAGGTTCTCGTATTTTAGAAAACTTTGTTGTCGATATCTGTAAATGTGAAAAATTATGGACTTCAGCATCAATCA
TTGATGATGCAATTGCTAAAATGAAAGCACAAGTTGGTGATGACGAAGTTATTCTAGGCCTTTCAGGTGGTGTAGATTCA
TCAGTAGTTGCTATGTTATTACATCGTGCTATTGGCGATAAACTTACCTGTGTATTTGTTGATAACGGCTTACTTCGTTT
AGACGAAGGCCAGCAAGTAATGGATATGTTTGGTGATCACTTCGGTTTAAACATCATTAAGATTGAAGCTGAAGATAGAT
TTTTAAATCGTTTAGCGGGCGAAAGTGAGCCAGAAGCAAAACGTAAAATTATCGGTAACGTATTTATTGATGTGTTCGAA
GAAGAATCGAACAAGCTTGATAATGCAAAATGGTTAGCACAAGGCACTATTTATCCAGACGTAATTGAATCAGCAGCGTC
AGCTACGGGTAAAGCACATGTGATTAAATCACACCATAATGTTGGTGGTTTACCTGATTACATGAAATTAGGTTTAGTTG
AACCATTACGTGAATTATTTAAAGATGAAGTACGTAAAATTGGCTTAGAGCTAGGTCTACCATACGACATGCTTTATCGT
CACCCATTTCCTGGACCTGGTTTAGGTGTACGTATATTAGGTGAAGTGAAAAAAGAATACGCTGACTTATTGCGTCGTGC
CGATGCTATCTTCATTGAAGAATTGCACAAGCATGATTTATATACAAAAGTAAGCCAAGCCTTTACCGTATTCTTACCAG
TAAAATCAGTGGGCGTTATGGGCGATGCGCGTAAATATGATTGGGTTGTATCTTTACGTTGTGTTGAAACAATCGACTTT
ATGACGGCGCGTTGGTCACACTTACCATATGATTTCTTAGGCTTGGTTTCTAACCGAATTATTAATGAAATTGATGGTAT
TTCTCGCGTAGTTTACGATATATCAGGTAAGCCGCCTGCCACCATAGAGTGGGAGTAA

Protein sequence :
MSKDIHDHRILILDFGSQYTQLIARRVREIGVYCELWSWDVTEEQIKGFNPTGIILAGGPESVTEANSPRAPEYVYTAGV
PVLGICYGMQTMAEQLGGGVESSSHKEFGYAAVELIAQSALFNKVEDSIGDNGNALLDVWMSHGDKVSAIPEGFVTVAQT
ASCAYGAMANEEKQFYGVQFHPEVTHTKQGSRILENFVVDICKCEKLWTSASIIDDAIAKMKAQVGDDEVILGLSGGVDS
SVVAMLLHRAIGDKLTCVFVDNGLLRLDEGQQVMDMFGDHFGLNIIKIEAEDRFLNRLAGESEPEAKRKIIGNVFIDVFE
EESNKLDNAKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRILGEVKKEYADLLRRADAIFIEELHKHDLYTKVSQAFTVFLPVKSVGVMGDARKYDWVVSLRCVETIDF
MTARWSHLPYDFLGLVSNRIINEIDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-128 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-109 47