Gene Information

Name : leuS (CPS_1722)
Accession : YP_268460.1
Strain : Colwellia psychrerythraea 34H
Genome accession: NC_003910
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1768334 - 1770925 bp
Length : 2592 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGAAGCCATTTATAATCCCCAAGCGATTGAAGCAACAGTACAAAAATTTTGGACTGATAACAACACTTTTCAAGCTAT
TGAAAACCCAGACAAAGAAAAATTTTACTGCTTAGCTATGTTCCCTTACCCAAGTGGTCGATTGCACATGGGTCATGTAC
GTAATTACAGCTTAGGTGATGTTATTTCTCGCTACCAACGTATGCAAGGCAAAAATGTCATGCAACCAATGGGTTGGGAT
GCTTTTGGTTTACCCGCTGAAAATGCTGCGATTAAAAACAAAACAGCGCCAGGGAAATGGACCTATGAAAATATTGACTA
CATGCGTAATCAATTACAATCACTAGGTTTTGGTTATGACTGGGGCCGTGAGTTAGCTACCTGTAAACCTGATTACTATC
GCTGGGAACAGTGGTTCTTTACCCAGCTTTTCGAAAAAGGTTTAGTGTATAAGAAAAATGCCACGGTAAACTGGGATCCA
GTCGATCAAACTGTACTTGCAAACGAACAAGTGATTGACGGTAGAGGCTGGCGTTCAGGTGCTCTAGTTGAGCGTAAACA
AATTCCACAATGGTTTATTAAAATCACTGATTACGCCGAAGAATTACTTGATGATTTAGATCAATTAACCGAATGGCCTG
AGCAAGTAAAAACCATGCAACGTAATTGGATTGGTCGCTCTCAAGGTGTTGAGATGACTTTTGCCGTTGCTGACTCGACT
GAAAGCTTTGATATTTACACCACTCGACCTGATACGTTAATGGGTGTTACTTATGTTGCGCTTGCCGCTCAGCATCCTTT
AGCAGTAGCTGCCGCCGTGGATAATGCAGATTTAGCTGCTTTTATTGATGAATGTAAAAACAGTAAAACCACTGAAGCTG
ATATGGCTGCAATGGAAAAGAAAGGTGTTGATACCGGTCTTAAAGCCATTCACCCGCTTACCGGTAAATTAGTGCCCGTT
TGGGCCGCTAACTTTGTGCTAATGGATTATGGCTCAGGTGCTGTAATGTCTGTACCAGGACATGATCAACGCGATTATGA
ATTTGCGCTTAAATATGGTTTGGCTATTGAGCAAGTTATTGCTGGGCAAGAGGCTGATGATATTAACAAGGCTGCTATCA
CTGAAAAATCTACCTTAATCAATTCTGGTGAATTTGATGGCTTAGATTTTGAAGAAGCGTTTAAAGCCATCAGCGACAAG
TTAATCAGCGAAAACAAAGGTAAAACGACGACTAACTACCGCTTACGTGATTGGGGTGTTTCTCGTCAACGTTATTGGGG
TACGCCAATTCCAATGATTAACCTTGCCAATGGTGAGTCAGTACCCGTACCGACAAATGAATTACCGGTAGTATTGCCAG
AAGATGTGGTAATGAATGGCACCACTTCACCGATTAAAGCAGATCCAGAATGGGCAAAAACCCTTTATAACGGTGAAGAA
GCCCTTCGTGAAACCGATACCTTTGATACCTTCATGGAGTCTTCTTGGTATTACGCACGTTATTGTTCACCAAATGACGA
CACCCAAATGATTGATCCTGCCAAAGCAAACTACTGGTTGCCAGTAGATCAATATATTGGTGGTATCGAACATGCAATCC
TACATTTATTATACTCTCGCTTCTTCCATAAGTTATTGCGAGATGTCGGTTTAGTTAAATGTGACGAACCGTTTAAAAAG
CTTTTATGTCAAGGCATGGTGTTAGCTGAAACCTACTATCGTGAAGCTGACAACGGCGCACAAGAGTGGATTGCACCAAC
GGATGTTGAAGTTGAGCGTGACGAAAAAGGTCAAATAACTTCATCCATTAGTAAAATTGACGGCCAACCTGTGTTATCTG
CAGGTATGAGCAAAATGTCTAAATCGAAAAACAACGGTATTGACCCACAAGAAGTTATCGAGAAATACGGTGCTGATACG
GTACGTTTATTTATCATGTTCACTTCACCACCAGAGCAAACCTTAGAATGGTCTGATGCCGGTGTTGAAGGCGCACATCG
TTTTGTGAAACGTGTTTATAAATTAGCGCATGAATTTGTTGAAAGTACCAATAACTCTGCCGTGGTCGATATTGCTGAGT
TAACATTAAACGCTGATCATAAAAAGCTGCGTCGTGAGTTACATAAGACCATTGCGAAAGTGACCGACGATATAGGTCGT
CGCAATACTTTCAATACCGCCATTGCTGCCATTATGGAGTTAATGAATCATTTGGGCAAAGCTAAAGTAAACAGTGATGA
AGATAAAGCGGTAATGCAAGAAGCTGTTCGCGCAGTGGTATTAATGTTAACGCCAATTACCCCACATCTATGTCACCATT
TATGGCAATTAGTTGGCGGTAGTGATGAGAATGTTGAAGATGCTAGCTGGCCTGTCGTCGACAATAGTGCTTTAGTTGAA
GATGAAAAACTTATCATTGTACAAGTTAACGGCAAGGTACGTGCAAAAATAACTGTTGCCGCCGATGCGAGTAAAGAAGA
TGTTGAGGCACTTGGCTTAAATGATGAAAGCGTTTTGAAATTTACTGATGGTAACACCATACGCAAAGTTATTTATATTC
CAGGTAAATTACTTAATATTGTCGCCAACTAA

Protein sequence :
MEAIYNPQAIEATVQKFWTDNNTFQAIENPDKEKFYCLAMFPYPSGRLHMGHVRNYSLGDVISRYQRMQGKNVMQPMGWD
AFGLPAENAAIKNKTAPGKWTYENIDYMRNQLQSLGFGYDWGRELATCKPDYYRWEQWFFTQLFEKGLVYKKNATVNWDP
VDQTVLANEQVIDGRGWRSGALVERKQIPQWFIKITDYAEELLDDLDQLTEWPEQVKTMQRNWIGRSQGVEMTFAVADST
ESFDIYTTRPDTLMGVTYVALAAQHPLAVAAAVDNADLAAFIDECKNSKTTEADMAAMEKKGVDTGLKAIHPLTGKLVPV
WAANFVLMDYGSGAVMSVPGHDQRDYEFALKYGLAIEQVIAGQEADDINKAAITEKSTLINSGEFDGLDFEEAFKAISDK
LISENKGKTTTNYRLRDWGVSRQRYWGTPIPMINLANGESVPVPTNELPVVLPEDVVMNGTTSPIKADPEWAKTLYNGEE
ALRETDTFDTFMESSWYYARYCSPNDDTQMIDPAKANYWLPVDQYIGGIEHAILHLLYSRFFHKLLRDVGLVKCDEPFKK
LLCQGMVLAETYYREADNGAQEWIAPTDVEVERDEKGQITSSISKIDGQPVLSAGMSKMSKSKNNGIDPQEVIEKYGADT
VRLFIMFTSPPEQTLEWSDAGVEGAHRFVKRVYKLAHEFVESTNNSAVVDIAELTLNADHKKLRRELHKTIAKVTDDIGR
RNTFNTAIAAIMELMNHLGKAKVNSDEDKAVMQEAVRAVVLMLTPITPHLCHHLWQLVGGSDENVEDASWPVVDNSALVE
DEKLIIVQVNGKVRAKITVAADASKEDVEALGLNDESVLKFTDGNTIRKVIYIPGKLLNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-159 43