Gene Information

Name : megL (CPS_1705)
Accession : YP_268443.1
Strain : Colwellia psychrerythraea 34H
Genome accession: NC_003910
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 1748616 - 1749857 bp
Length : 1242 bp
Strand : -
Note : identified by match to protein family HMM PF01053; match to protein family HMM TIGR01328

DNA sequence :
ATGACCCAATTTAAGAGCAAAAATATTGAAACTAACGCTATTCATGCCGGCAGAATTAATGATACACAGTTTGGCTCGCT
TGCTACGCCTTTATATCAAACATCTACGTTCATCTTTGATAATGCTCAGCAAGGTGGCGACCGTTTTGCCGGTGAAAGCG
AAGGTTATATTTACACGCGCTTAGGTAACCCAACAACTCGCCAATTAGAACAGCGCGTTGCGGCTATGGAATGCATGGAT
GATGCAGCTGCAACCGCAACAGGTATGGCTGCTGTCTCAGCAGCGTTACTGACTAACTTGCAAGCTGGCGATCATATGAT
TTCATCTAAAGCTGTTTATGGTTGCTCATTCGCGCTAATGAATCACATGCTGAAGAAGTTTAATATCGAGGTGACGTTTG
TCGATATGACTGAGCCTGACAATATCAAAGCAGCCATCAAAGAAAATACTAAGTTAGTCTTTTTAGAAACCCCCATCAAT
CCAAACTTAGTGGTATTAGATTTGGAAAAAATTTGCGCCATTGCCAAAGCGCACAACTTATTATCAATAGTAGACAATAC
TTTCCTTACCCCTGTATTACAACAGCCTGCAAAATTTGGTGCTGATATTGTGGTGCATAGTGCAACTAAATACCTTAATG
GTCATGGTGATGTTGTCGCCGGTGTCGTCTGTGCTAATTTTGAAATGATCAACGAAATAAAAATGACGACCCTTAAAGAT
ATCGGTGCCACCATAAGTCCTCATGATGCTTGGTTGATTATGCGCGGCCTTAAAACTTTGCCGATTCGAATGGATAGACA
TTGTAGCAATGCACAAACAGTCGCAGAGTTTTTAGAACAACACCCTATGGTTGATGAAGTTTACTATCCTGGTCTTAAAA
GTCACTCTGGGAACAAGTTTGTGGGTAATCAAATGAAAGCCGCAGGTGGTGTAATTGCTTTTGAATTAAATACCGACTTG
ACGGGTGGAAAAACCTTTATTGATGCAATGGAGCTTTTTTCAATTGCCGTCAGCTTAGGTGATGCAGAGTCATTAATTCA
ACACCCTGCGTCAATGACACACTCGCCTTATACCCCCGAAGAAAGAGCAGATGCGGGCATCAGTGATAGTTTAATTAGAA
TCTCTGTAGGTTTAGAGAATGTCGATGATATTATCAGTGATTTAACCCAAGCTTTGGAAAAAGTGAAACTGCCAAGCAGC
GATAAAGTTACCAATATTAATCAAGCAAATAATGCAGCATAA

Protein sequence :
MTQFKSKNIETNAIHAGRINDTQFGSLATPLYQTSTFIFDNAQQGGDRFAGESEGYIYTRLGNPTTRQLEQRVAAMECMD
DAAATATGMAAVSAALLTNLQAGDHMISSKAVYGCSFALMNHMLKKFNIEVTFVDMTEPDNIKAAIKENTKLVFLETPIN
PNLVVLDLEKICAIAKAHNLLSIVDNTFLTPVLQQPAKFGADIVVHSATKYLNGHGDVVAGVVCANFEMINEIKMTTLKD
IGATISPHDAWLIMRGLKTLPIRMDRHCSNAQTVAEFLEQHPMVDEVYYPGLKSHSGNKFVGNQMKAAGGVIAFELNTDL
TGGKTFIDAMELFSIAVSLGDAESLIQHPASMTHSPYTPEERADAGISDSLIRISVGLENVDDIISDLTQALEKVKLPSS
DKVTNINQANNAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-62 41
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-63 41
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-61 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL YP_268443.1 methionine gamma-lyase BAC0207 Protein 4e-86 48