Gene Information

Name : spH (BCE_0745)
Accession : NP_977070.3
Strain : Bacillus cereus ATCC 10987
Genome accession: NC_003909
Putative virulence/resistance : Virulence
Product : sphingomyelinase C
Function : -
COG functional category : -
COG ID : -
EC number : 3.1.4.12
Position : 769743 - 770879 bp
Length : 1137 bp
Strand : +
Note : identified by match to protein family HMM PF03372

DNA sequence :
ATGCACAACGTGTTACTGCTGGATACATTCAGCTTTGGTTTGATACGTACGGAGATCGTTAAGTATTTAAAAAAGGTCAA
ATCTCACAATAGAGTATTTGACCTTTTTATTACTATACAAATGGAGGTATGGAACGTGAAAGGTAAATTGCTAAAAGGTG
TACTTAGCTTTGGGATTGGTTTAGGAGTTTTATACGGAGGTTCTTCAGTGCAAGCAGATACGTCTACAGATCAAAACAAC
ACTTTGAAAGTGATGACGCACAACGTGTATATGCTATCAACTAACTTATATCCGAACTGGGGACAAAGTCAGCGTGCCGA
TTTAATTGGGGCGGCAGATTATATTAAGAATCAGGATGTAGTTATATTAAATGAAGTGTTCGATAATAGCGCATCAGATC
GTTTGTTAGGGAATTTGAAGAAAGAATATCCAAATCAAACAGCAGTATTAGGTCGTAGTAATGGAAATGAATGGGATAAA
ACGTTAGGTAGCTATTCATCTTCAACGCCTGAAGATGGAGGCGTTGCAATCGTGAGTAAATGGCCGATCGTTGAAAAGAT
TCAATATGTATTTGCAAAAGGATGCGGACCAGATAATTTATCAAATAAAGGGTTTGTATACACGAAAATTAAGAAAAATG
ATCGTTTCGTTCATGTGATTGGGACACACTTGCAGGCTGAAGATAGTATGTGTGGAAAAACTTCACCTGCATCTGTACGT
ACAAACCAGCTAAAAGAAATTCAAGATTTTATTAAAAATAAGAATATACCAAATGACGAGTACGTTCTATTTGGTGGTGA
TATGAACGTGAATAAAATAAATGCAGAGAACAATAGTGACTCAGAGTACGCATCCATGTTTAAAACATTGCATGCGTCAA
TTCCATCTTATACGGGACATACAGCAACTTGGGATGCAACGACAAACAGTATTGCAAAATATAATTTCCCTGATAGTCCT
GCCGAGTATTTAGATTATATTATTGCAAGTAAGGACCATGCGAATCCATCATTTATAGAGAATAAAGTATTACAACCAAA
ATCTCCACAGTGGACTGTTACATCATGGCTCAAAAAATATACGTATGATGATTATTCTGATCATTATCCAGTAGCAGCAA
CTATTTCTATGAAGTAG

Protein sequence :
MHNVLLLDTFSFGLIRTEIVKYLKKVKSHNRVFDLFITIQMEVWNVKGKLLKGVLSFGIGLGVLYGGSSVQADTSTDQNN
TLKVMTHNVYMLSTNLYPNWGQSQRADLIGAADYIKNQDVVILNEVFDNSASDRLLGNLKKEYPNQTAVLGRSNGNEWDK
TLGSYSSSTPEDGGVAIVSKWPIVEKIQYVFAKGCGPDNLSNKGFVYTKIKKNDRFVHVIGTHLQAEDSMCGKTSPASVR
TNQLKEIQDFIKNKNIPNDEYVLFGGDMNVNKINAENNSDSEYASMFKTLHASIPSYTGHTATWDATTNSIAKYNFPDSP
AEYLDYIIASKDHANPSFIENKVLQPKSPQWTVTSWLKKYTYDDYSDHYPVAATISMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 2e-70 59
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 1e-70 59
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 2e-70 59
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 2e-77 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spH NP_977070.3 sphingomyelinase C VFG1798 Protein 9e-78 58
spH NP_977070.3 sphingomyelinase C VFG0674 Protein 1e-77 54