Gene Information

Name : megL (BCE_4791)
Accession : NP_981084.1
Strain : Bacillus cereus ATCC 10987
Genome accession: NC_003909
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 4435050 - 4436228 bp
Length : 1179 bp
Strand : -
Note : identified by match to protein family HMM PF01053; match to protein family HMM TIGR01328

DNA sequence :
ATGAAAAAGAAGCATATGGAGACAGCGTTAATTCATCACGGTTATACATCAGAGGAATATAAAGGAAGTTTGACACCGCC
TTTATTTCAAACGTCTACATTTACATTTGAGACTGCGCAGCAAGGAGAAGCGAGTTTTGCGGGAGTGGATCCATCTTATA
TTTACTCAAGACTTGGAAATCCAACTGTGAAATTATTTGAAGAACGTATGGCGGTGTTAGAAGGAGGAGAAGAAGCTCTT
GCTTTCGGATCTGGTATGGCAGCTATTTCCGCAACGTTAATTGGTTTTCTAAAAGCTGGAGATCATATTATTTGTTCAAA
TGGATTATACGGATGCACGTACGGCTTTTTGGAAGTGTTGGAAGAAAAATTTATGATTACGCATTCGTTTTGTGATATGG
AGACAGAGGCTGATATGGAAAATAAAATTCGCCCAAATACAAAGCTTATTTTCGTTGAAACACCGATTAATCCGACAATG
AAATTAATTGATTTAAAACAAGTGATTCGGGTTGCGAAGCGAAATGGTTTACTTGTCATTGTTGACAATACGTTTTGTTC
ACCTTATTTACAAAGACCGCTTGAACTTGGTTGTGACGCCGTTGTTCATAGTGCGACAAAATATATTGGTGGTCACGGTG
ACGTTGTAGCGGGTGTAACAATTTGTAAAACGAAAGCGTTAGCTGAAAAGATTCGCCCGATGCGAAAAGATATCGGCGGT
ATTATGGCGCCGTTTGATGCGTGGTTATTGTTACGCGGATTAAAGACACTAGCGGTAAGAATGGACCGCCATTGTGATAA
TGCAGAAAAAATTGTATCGTTTCTAAAAAATCATGATGCGGTAGAAGGTGTTTGGTACCCAGAAGGAGAGTTAGCATCTC
GCCAAATGAAACGTGGGGGCGGCGTTATATCTTTTTCAATTAAAGGTGGGAAAGAAGAGACGCAGGCGTTTATTAATGAC
CTTCACTTTATTACAATTGCGGTAAGTTTAGGAGATACAGAAACGTTAATTCAGCATCCGGCAACGATGACGCACGCTGC
GATTCCAGCTGCGTTAAGACAAGAAATGGGCATTTATGATAATTTAATACGTTTATCTGTCGGTTTAGAATCTTGGGAGG
ATATCGTTTCTGATTTAGAGCAAGCGTTAAAGAAAATATCTACTGTTAGTAATCAATAA

Protein sequence :
MKKKHMETALIHHGYTSEEYKGSLTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEAL
AFGSGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADMENKIRPNTKLIFVETPINPTM
KLIDLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTKALAEKIRPMRKDIGG
IMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWYPEGELASRQMKRGGGVISFSIKGGKEETQAFIND
LHFITIAVSLGDTETLIQHPATMTHAAIPAALRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKISTVSNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-67 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-68 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL NP_981084.1 methionine gamma-lyase BAC0207 Protein 1e-88 47