Gene Information

Name : metC (BCE_4454)
Accession : NP_980747.1
Strain : Bacillus cereus ATCC 10987
Genome accession: NC_003909
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 4126112 - 4127245 bp
Length : 1134 bp
Strand : -
Note : identified by match to protein family HMM PF01053

DNA sequence :
ATGAGAGCAAAGACAAAGTTAATTCATGGTATTCGCATAGGAGAACCTTCAACTGGATCTGTAAATGTACCGATTTATCA
AACGAGTACGTACAAACAAGAAGCAGTTGGTAAGCATCAAGGATATGAATATTCACGTACAGGCAACCCAACACGTGCAG
CTTTAGAAGAAATGATTGCGGTATTAGAAAACGGCCATGCTGGTTTCGCATTTGGTTCAGGAATGGCGGCTATTACAGCT
ACGATTATGTTGTTCTCAAAAGGTGACCACGTTATTTTAACAGATGATGTGTATGGCGGAACGTACCGCGTGATTACGAA
AGTATTAAACCGTTTCGGTATTGAGCATACATTTGTAGATACAACAAACTTAGAGGAAGTTGAAGAAGCGATTCGTCCAA
ATACGAAAGCGATTTATGTAGAAACACCAACGAATCCGTTACTAAAAATTACTGATATTAAAAAAATATCTACTCTTGCT
AAAGAGAAAGATTTATTAACAATTATTGATAACACATTCATGACGCCATATTGGCAGTCGCCGATTTCTTTAGGAGCAGA
CATTGTACTTCATAGTGCAACGAAATATTTAGGAGGTCATAGTGACGTAGTTGCAGGTCTAGTAGTTGTAAATAGCCCGC
AATTAGCAGAAGACCTTCACTTTGTACAAAACTCAACAGGCGGCATTCTTGGCCCGCAAGATAGTTTCTTACTACTTCGT
GGTTTAAAAACATTAGGAATTCGAATGGAAGAGCATGAAACGAATTCACGTGCAATTGCTGAGTTTTTAAATAACCACCC
AAAAGTAAATAAAGTATATTACCCAGGCCTTGAGTCACATCAAAACCATGAACTGGCAACAGAACAAGCAAATGGATTTG
GTGCTATTATCTCATTTGATGTAGATAGCGAAGAAACATTAAATAAAGTGCTTAAGAAATTACAATACTTTACGCTGGCT
GAAAGTTTAGGAGCAGTAGAAAGTTTAATTTCTATCCCCTCTCAAATGACGCATGCATCAATCCCAGCAGATCGTCGCAA
AGAATTAGGAATTACAGATACATTAATTCGAATTTCTGTCGGTATTGAAGACGGAGAAGATTTAATTGAAGATTTAGCAC
AAGCGTTAGCGTAG

Protein sequence :
MRAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKHQGYEYSRTGNPTRAALEEMIAVLENGHAGFAFGSGMAAITA
TIMLFSKGDHVILTDDVYGGTYRVITKVLNRFGIEHTFVDTTNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTLA
KEKDLLTIIDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNSTGGILGPQDSFLLLR
GLKTLGIRMEEHETNSRAIAEFLNNHPKVNKVYYPGLESHQNHELATEQANGFGAIISFDVDSEETLNKVLKKLQYFTLA
ESLGAVESLISIPSQMTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-114 61
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-116 61
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-82 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC NP_980747.1 cystathionine beta-lyase BAC0207 Protein 4e-65 41