Gene Information

Name : guaA (XCC2183)
Accession : NP_637539.1
Strain : Xanthomonas campestris ATCC 33913
Genome accession: NC_003902
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2573881 - 2575446 bp
Length : 1566 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCAGTCTGCATAACGACAAGATCCTCATCCTCGATTTCGGCGCGCAGTACACCCAGCTGATCGCGCGGCGGATTCG
CGAAATTGGCGTGTACTGCGAGATCTGGGCCTGGGATCATGATCCGAGCGAGATCGCCGGGTTCGGTGCCAAGGGCATCA
TTCTCTCGGGTGGTCCCGAGTCGACCACCTTGCCAGGGGCGCCGGTTGCGCCGCAGGAGGTGTTCGATAGCGGCTTGCCG
GTGTTCGGTATTTGCTACGGCATGCAGACACTGGCTGCGCAGTTGGGCGGTGCCACCGAGGCGGCCGATCAGCGCGAGTT
CGGTCATGCCGAAGTCGATGTAGTGGCGGCCGATGCACTGTTCTCTGGTCTGACCGACCACGCCGGCGCGTCGCGCCTGA
ATGTGTGGATGAGCCACGGCGACCACGTGTCGCAGGTGCCGCCGGGCTTCACGATTACTGCCGTGACCGACCGTATTCCG
GTGGCGGCGATGTCCAACGAAGACAAGCGCTGGTATGGCGTGCAGTTCCACCCGGAAGTGACACATACGCTGCAGGGCCA
GACCTTGCTGCGGCGCTTCGTGGTGGACGTGTGTGGCTGCCAGACGCTGTGGACCGCGGCCAACATCATCGATGACCAGA
TTGCGCGCGTGCGCGAGCAGGTGGGCGACGATGAAGTGATTCTGGGCTTGTCCGGAGGTGTGGATTCGTCGGTGGTCGCG
GCACTGCTGCACAAGGCGATCGGTGACAAGCTGACCTGCGTGTTCGTCGACACCGGCCTGCTGCGTTGGCAGGAAGGCGA
CCAGGTGATGGCGATGTTTGCCGAGCACATGGGCGTCAAGGTGATCCGCGTCAATGCGGCCGACCGCTACTTCGCCAAAC
TCGAAGGCGTGAGCGATCCTGAAGCCAAGCGCAAGATCATCGGCAACCTGTTCGTGGATATCTTCGATGAAGAATCCAAC
AAGCTGGCCAATGCCAAGTGGCTGGCGCAGGGCACGATTTATCCGGACGTGATCGAGTCGGCCGGCAGCAAGACCGGTAA
GGCGCACGTGATCAAGAGCCACCACAACGTGGGTGGCCTGCCTGAGCACATGAAGCTGGGCCTGGTCGAACCGCTGCGCG
AACTGTTCAAGGACGAAGTGCGTCGCCTGGGCGTGGAACTCGGCCTGCCACGCACCATGGTGTATCGCCATCCATTCCCG
GGCCCGGGCCTGGGTGTGCGCATCCTGGGCGAGGTGAAGCGCGAATACGCCGAACTGCTGGCCAAGGCCGATGCGATCTT
CATCGACGAGCTGCGCAAGGCGGACCTGTACGACAAGACCAGCCAGGCATTCGCGGTGTTCCTTCCGGTTAAGTCGGTGG
GTGTGGTGGGCGATGCGCGCGCCTATGAATGGGTGATCGCACTGCGTGCGGTGGAGACCATCGACTTCATGACCGCGCAT
TGGGCGCACCTGCCATACGACTTCCTCGGCACGGTGAGCAACCGCATCATCAACGAACTGCGCGGCGTCTCGCGCGTGGT
CTACGACATCTCCGGCAAACCGCCTGCGACGATCGAGTGGGAGTGA

Protein sequence :
MSSLHNDKILILDFGAQYTQLIARRIREIGVYCEIWAWDHDPSEIAGFGAKGIILSGGPESTTLPGAPVAPQEVFDSGLP
VFGICYGMQTLAAQLGGATEAADQREFGHAEVDVVAADALFSGLTDHAGASRLNVWMSHGDHVSQVPPGFTITAVTDRIP
VAAMSNEDKRWYGVQFHPEVTHTLQGQTLLRRFVVDVCGCQTLWTAANIIDDQIARVREQVGDDEVILGLSGGVDSSVVA
ALLHKAIGDKLTCVFVDTGLLRWQEGDQVMAMFAEHMGVKVIRVNAADRYFAKLEGVSDPEAKRKIIGNLFVDIFDEESN
KLANAKWLAQGTIYPDVIESAGSKTGKAHVIKSHHNVGGLPEHMKLGLVEPLRELFKDEVRRLGVELGLPRTMVYRHPFP
GPGLGVRILGEVKREYAELLAKADAIFIDELRKADLYDKTSQAFAVFLPVKSVGVVGDARAYEWVIALRAVETIDFMTAH
WAHLPYDFLGTVSNRIINELRGVSRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-126 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-126 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-126 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-113 49