Gene Information

Name : MM_0865 (MM_0865)
Accession : NP_632889.1
Strain : Methanosarcina mazei Go1
Genome accession: NC_003901
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1021868 - 1023136 bp
Length : 1269 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGAACTTAAATTTGTACGTAACAACCCCGACATAGTTGGGCGTGCTCTTATTAGCAGGAATATGGGCACAGAGCT
TATTGATAGCCTTCTTGAATATGACGCAGCCTGGAGGGAATGTCTCATCGAGGGCGATGACCTGAAGCACAAGCGTAATG
TTGTCACCCGCGAGATAGCGCAGCTCAAGAAGGAAAATAAAGACGCTGCATCCAGAATAAATGAAATGCAGGGCATTAAC
AGCCGTATTAAAGAGCTGGATGACAAAATACGCGATTACAAATCAAAAATAAATGAAATAATGCTAAGTATTCCAAATAT
TCCTTCTGAAACCACGCCTGTAGGCAAGGATGAGAATGACAATCCGGTTGTAAGGGTAGTTGGAGAACCAAGGGAGTTCA
CATTTACTCCAAAGCCGCACTGGGAAATAGGAGAATCTCTGGATATCCTTGACTTTGAAAGAGCAGCTAAGATATCAGGC
CAGGGTTTTGCAGTCTATAAAGGTATGGGCGCAAAGCTTGAGAGAGCTCTCATAAACTTCATGCTTGATGTGCACACCAG
GCAGGGTTATCTTGAAGTTTTTCCTCCTGTGCTTATTAATGAGAAAGCCATGACTGGTACAGGCCAATTACCCAAGTTTA
AAGACGATATGTACGGATGCACTGATGGTTTCTATCTTGCGCCTACTGCAGAAGTGCCTGTAACCAACCTCTTCATGGAT
GAATATATGGAAAACCTGCCGGTATTTCTTACAGCATACACTGCCTGTTTCAGGCGTGAGGCAGGAAAACATGGTCAGGA
TACCAGAGGTATCATCCGCAACCACCAGTTCAATAAGGTTGAACTTGTTAAATTCGTAATGCCTGAAACATCCTATGAAG
AACTGGAAAAACTTACTCTTGATGCTGAAGAGATCCTCAAACTCCTTAAGTTACCATATCGGGTAGTAAGCCTCTGTACT
GGCGATCTGGGATTCTCGGCTGCCAAGACTTACGACCTCGAAGTATGGGTACCTACACAGGAAAAGTATAGAGAAATCTC
TTCGTGCTCTAATTTCGATAATTTCCAGGCAAGGAGAGCCAACATCCGCTACAGGACTCCTGAAGGGCCACAGTTCGTTC
ACACGCTCAACGGTTCGGGACTTGCTGTCGGCAGGACGGTTGTTGCAATACTGGAGAACTACCAGCGTGAAGACGGCAGT
GTCGAAATTCCGGAAGTCCTCAGGCCTTACATGGGTGGGGCAGAAGAAATTAGAAAAGTTTGCCATTGA

Protein sequence :
MLELKFVRNNPDIVGRALISRNMGTELIDSLLEYDAAWRECLIEGDDLKHKRNVVTREIAQLKKENKDAASRINEMQGIN
SRIKELDDKIRDYKSKINEIMLSIPNIPSETTPVGKDENDNPVVRVVGEPREFTFTPKPHWEIGESLDILDFERAAKISG
QGFAVYKGMGAKLERALINFMLDVHTRQGYLEVFPPVLINEKAMTGTGQLPKFKDDMYGCTDGFYLAPTAEVPVTNLFMD
EYMENLPVFLTAYTACFRREAGKHGQDTRGIIRNHQFNKVELVKFVMPETSYEELEKLTLDAEEILKLLKLPYRVVSLCT
GDLGFSAAKTYDLEVWVPTQEKYREISSCSNFDNFQARRANIRYRTPEGPQFVHTLNGSGLAVGRTVVAILENYQREDGS
VEIPEVLRPYMGGAEEIRKVCH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-114 55