Gene Information

Name : MM_3085 (MM_3085)
Accession : NP_635109.1
Strain : Methanosarcina mazei Go1
Genome accession: NC_003901
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3745285 - 3746469 bp
Length : 1185 bp
Strand : -
Note : -

DNA sequence :
ATGGAAAGGAAATTTAAGTTCGCAACCCAATGCGTTCATGCGGGAGAAAAACCGGATCCGGTATTCGGAGCTCATACAAC
TCCAATATTTCAAACTTCAACTTTCATTTTTGATAGTGTTGAACAGGGAGCTTCAAGATTTGCAGAAGAGGAAGACGGGT
ATGTCTATACGCGCATTCCCCCGAACACGCCCACACACGCCGTCCTGTCAGAAAAGTTCGCTGCACTCGAAGGAGGGGAA
GCAGGGCAGACCTTTGCTTCAGGAATGGCAGCAATCACTGCAGTTGCTCTGACAGCCCTCAAAAAGGGAGACCACCTGGT
CTCAACTGATGTGGTCTACGGATGCACCTACAGCCTTTTTTCAGAAATTCTTCCCGGGCTCGGGATAGATGTTACTTTCG
TAGACACAACAGATGCGGAAAACGTGAGAAAAGTTCTCAGGCCGGAGACTAAAATGGTTTTTCTGGAAACTCCTGCCAAC
CCTACCCTGAATGTATGTGATATCAGAATGATTTCCGGGCTTGCAAAAGCACAGGGAGCCATCTGTGTTGTGGATAACAC
ATTTTCCACGCCTTATTTCCAGAAACCTCTTCTTCTTGGGGCAGATATTTCCCTCAGCAGCTGTACAAAATATATAGGCG
GGCATGCAGATCTGCTTGGCGGAATCATTGTATGCGACAAAGCTTTTCTAAAAAATCTGGCAAAGGTTGCCGGATATACG
GGCGGAACAATGGGCTTGCACGAAGCCTGGCTCTGCATAAGAGGGCTGAAAACCCTCCATATCAGGATGGAAAGACACGC
CGAGAACGCGCTGAAGGTTGCTAACTTCCTTGAGTCTCATCCCGCAGTTGAATGGGTAAGATACCCCGGGCTTTCATCCC
ATCCGCAGCACGAAATCGCAAAAAAACAGATGAGCGGGTACGGAGGGATGCTTTCTTTCGGAGTAAAGGACGGGATTGAT
GCCGGAAGCAAGCTCATGAACAGCGTCAGGCTCTGTTCTCTCGCAGTAAGCCTCGGGGCAACTGATACCCTGATTCAGCA
TCCTGCTTCCATGACGCATGCCTGCGTCCCGAAAGAAGTAAGAGGAAAAGTGGGTATTACTGATGGGCTTGTCAGGCTTT
CCATAGGAATCGAAGACCCTGAGGACATAATTGCAGACCTCAAACAGGCGCTTGAGAAAATTTGA

Protein sequence :
MERKFKFATQCVHAGEKPDPVFGAHTTPIFQTSTFIFDSVEQGASRFAEEEDGYVYTRIPPNTPTHAVLSEKFAALEGGE
AGQTFASGMAAITAVALTALKKGDHLVSTDVVYGCTYSLFSEILPGLGIDVTFVDTTDAENVRKVLRPETKMVFLETPAN
PTLNVCDIRMISGLAKAQGAICVVDNTFSTPYFQKPLLLGADISLSSCTKYIGGHADLLGGIIVCDKAFLKNLAKVAGYT
GGTMGLHEAWLCIRGLKTLHIRMERHAENALKVANFLESHPAVEWVRYPGLSSHPQHEIAKKQMSGYGGMLSFGVKDGID
AGSKLMNSVRLCSLAVSLGATDTLIQHPASMTHACVPKEVRGKVGITDGLVRLSIGIEDPEDIIADLKQALEKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-76 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-77 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-62 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MM_3085 NP_635109.1 cystathionine gamma-synthase BAC0207 Protein 1e-77 45