Gene Information

Name : MM_2198 (MM_2198)
Accession : NP_634222.1
Strain : Methanosarcina mazei Go1
Genome accession: NC_003901
Putative virulence/resistance : Unknown
Product : type I restriction-modification system specificity subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 2611111 - 2612628 bp
Length : 1518 bp
Strand : +
Note : -

DNA sequence :
ATGAGTGATTTTGAAAAGCAATTGTGGAAAGCGGCAGACAAACTCCGAAAAAATATTGATGCTGCTGAGTATAAGCACAT
AGTTTTGGGCTTGATTTTTCTAAGATACATCTCAGATGCCTTTGAGGAATTATATGAAAAATTGCAACAGGGGGAAGGGG
AGTACGCCGGTGCAGACCCTGAAGACAGGGATGAATACAAAGCGGAGAATGTCTTTTTTGTCCCTGCAATTTCCCGCTGG
CCATATCTGCAATCAGAAGCCAAAAAACCGGATATCGGTAAATCTGTTGATAATGCAATGGATGCCATCGAAAAAGAGAA
TCCTCTGCTTAGAGGGGTTTTACCAAAGGTATTTGCACGGGGCAATCTTGACCCTACAAATCTTGGCGGTCTGATTGATC
TGGTGAGCAATGTTGCTCTTGGAGATGCCAAAAGCAGAAGTGCTGATGTTCTCGGTCATGTCTTCGAATATTTCCTTGGT
GAATTTGCTCTGGCAGAAGGAAAAAAGGGTGGACAGTTCTACACTCCGAGAAGCGTTGTTGAGTTACTGGTAGAGATGCT
GGAGCCCTACAATGGCCGGGTCTTTGACCCATGCTGCGGTTCCGGTGGCATGTTTGTGCAGTCAGAGAAGTTTGTTGCTG
ACCATCAGGGAAAAATAAACGATATATCGATCTACGGGCAGGAGAGCAATCAGACAACGTGGCGGTTGGCAAAGATGAAT
CTCGCCATCAGAAGCATTGACAGTTCCCAGGTTAAATGGAACAATGAAGGCTCTTTCCTCAATGATGTCCATAAAGACCT
GAAAGCGGATTATGTCATAGCCAATCCGCCGTTCAATGACAGCGACTGGAGTGGCGACCTGTTACGCAAGGACGGCAGGT
GGAAGTATGGTGTTCCTCCAGCCGGAAACGCTAATTATGCCTGGATACAGCATTTCCTTTATCATTTAGGTCCGAGCGGT
CAGGCCGGTTTTGTTCTGGCTAAGGGTTCTCTGACATCCAAATCATCGGGTGAGGGGGACATCAGAAAAGAGCTCGTAGA
GGCACGCCTGGTAGACTGCATAGTGAACCTTCCGCCAAAACTGTTCCTGAATACCCAGATCCCGGCAAGCCTCTGGTTCC
TGAGCAGGAATAAAGCCAACGGTAAGCACAGAAACAGGACTGATGAGATTCTGTTCATCGATGCACGGAACATGGGACAC
CTGATAAACCGCAGAACCCGTGAATTTTCACCTGAGGATATACAGCAGATTGCGGGCACCTACCATAAATGGCGCAATCC
GGAAGGGAATTACGAAGATGTGAAAGGATTCTGCAATTCCGCTCCAATTGAACGGGTACGTGAACTGGGCTATGTACTGA
CTCCGGGGCGCTATGTAGGATTGCCGGACGATGAAGATAATTTTGATTTCAATGAGCGCTTCTCCGCGCTGAAAGCCGAG
TTCGAGGAGCAGTTGAAAGAGGAAGAGAGACTGAACCTGCGGATCGCCGAGAATCTGAAAAAGGTGAAGCCGGCATGA

Protein sequence :
MSDFEKQLWKAADKLRKNIDAAEYKHIVLGLIFLRYISDAFEELYEKLQQGEGEYAGADPEDRDEYKAENVFFVPAISRW
PYLQSEAKKPDIGKSVDNAMDAIEKENPLLRGVLPKVFARGNLDPTNLGGLIDLVSNVALGDAKSRSADVLGHVFEYFLG
EFALAEGKKGGQFYTPRSVVELLVEMLEPYNGRVFDPCCGSGGMFVQSEKFVADHQGKINDISIYGQESNQTTWRLAKMN
LAIRSIDSSQVKWNNEGSFLNDVHKDLKADYVIANPPFNDSDWSGDLLRKDGRWKYGVPPAGNANYAWIQHFLYHLGPSG
QAGFVLAKGSLTSKSSGEGDIRKELVEARLVDCIVNLPPKLFLNTQIPASLWFLSRNKANGKHRNRTDEILFIDARNMGH
LINRRTREFSPEDIQQIAGTYHKWRNPEGNYEDVKGFCNSAPIERVRELGYVLTPGRYVGLPDDEDNFDFNERFSALKAE
FEEQLKEEERLNLRIAENLKKVKPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 4e-139 60
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-137 59
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 3e-139 59
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-107 46